Results 71 to 80 of about 242,283 (275)

Neuroinflammation trajectories precede cognitive impairment after experimental meningitis—evidence from an in vivo PET study

Journal of Neuroinflammation, 2020
Background Bacterial meningitis is a devastating central nervous system (CNS) infection with acute and long-term neurological consequences, including cognitive impairment.
Vijayasree V. Giridharan, Allan Collodel, Jaqueline S. Generoso, Giselli Scaini, Rico Wassather, Sudhakar Selvaraj, Rodrigo Hasbun, Felipe Dal-Pizzol, Fabricia Petronilho, Tatiana Barichello   +9 more
doaj   +1 more source

Cold Atmospheric Plasma Selectively Disrupts Breast Cancer Growth in a Bioprinted 3D Tumor‐Stroma Co‐Culture Model

Advanced Healthcare Materials, EarlyView.
This research introduces a cold plasma‐based platform for treating breast cancer bone metastases. Using a novel bioprinted 3D tumor‐stroma model, it highlights the selective antitumor effects of plasma‐generated reactive species. The platform aims to advance non‐invasive therapeutic strategies, offering potential clinical applications in controlling ...
Laura M. Bouret, Jean‐Baptiste Billeau, Michael H. Weber, Derek H. Rosenzweig, Stephan Reuter   +4 more
wiley   +1 more source

The use of mtCOI gene sequences in identifying Butis species in the Southwest of Vietnam

Heliyon, 2023
Butis genus is characterised by their small body size and morphological variability, allowing them to adapt to different habitats. This paper analyses the mitochondrial cytochrome C oxidase subunit I gene sequences and morphology of Butis for ...
Tran Thi Huyen Lam, Quang Minh Dinh, Van Thi Bich Truong, Ngon Trong Truong, Nam Sy Tran, Ton Huu Duc Nguyen   +5 more
doaj  

Genistein suppresses the mitochondrial apoptotic pathway in hippocampal neurons in rats with Alzheimer's disease

Neural Regeneration Research, 2016
Genistein is effective against amyloid-β toxicity, but the underlying mechanisms are unclear. We hypothesized that genistein may protect neurons by inhibiting the mitochondrial apoptotic pathway, and thereby play a role in the prevention of Alzheimer's ...
Yan Wang, Biao Cai, Jing Shao, Ting-ting Wang, Run-ze Cai, Chang-ju Ma, Tao Han, Jun Du   +7 more
doaj   +1 more source

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

Advanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li, Jiahui Li, Hasan Al Faruque, Paul Shami, Birgit Knoechel, Jens Lohr, Douglas Sborov, Jiyuan Yang, Jindřich Kopeček   +8 more
wiley   +1 more source

Advances in Photonic Materials and Integrated Devices for Smart and Digital Healthcare: Bridging the Gap Between Materials and Systems

Advanced Materials, EarlyView.
This article summarizes significant technological advancements in materials, photonic devices, and bio‐interfaced systems, which demonstrate successful applications for impacting human healthcare via improved therapies, advanced diagnostics, and on‐skin health monitoring.
Seunghyeb Ban, Hoon Yi, Jaejin Park, Yunuo Huang, Ki Jun Yu, Woon‐Hong Yeo   +5 more
wiley   +1 more source

Selective brain hypothermia-induced neuroprotection against focal cerebral ischemia/reperfusion injury is associated with Fis1 inhibition

Neural Regeneration Research, 2020
Selective brain hypothermia is considered an effective treatment for neuronal injury after stroke, and avoids the complications of general hypothermia.
Ya-Nan Tang, Gao-Feng Zhang, Huai-Long Chen, Xiao-Peng Sun, Wei-Wei Qin, Fei Shi, Li-Xin Sun, Xiao-Na Xu, Ming-Shan Wang   +8 more
doaj   +1 more source

Mechanochemistry for Metal–Organic Frameworks and Covalent–Organic Frameworks (MOFs, COFs): Methods, Materials, and Mechanisms

Advanced Materials, EarlyView.
An overview is provided of the mechanochemistry of metal‐organic frameworks (MOFs) and covalent‐organic frameworks (COFs), highlighting opportunities and strategies for discovery, synthesis and reactivity studies of these materials. Mechanistic studies and comparisons to the mechanochemistry of organic solids are outlined, showcasing how advances in ...
Joseph M. Marrett, Farshid Effaty, Xavier Ottenwaelder, Tomislav Friščić   +3 more
wiley   +1 more source

Effect of High Intensity Endurance Training on p53 and Cytochrome-c Gene Expression in Male Rat Soleus Muscle

Armaghane Danesh Bimonthly Journal, 2017
Background and aim: Recent research has suggested that exercise training is potential to influence the process of programmed cell death. However, little is known about the effect of high intensity endurance exercise on apoptotic factors.
F Seyedgomi, J Bashiri, F Gholami
doaj  

The Neuroprotective Effect of Hemin and the Related Mechanism in Sevoflurane Exposed Neonatal Rats

Frontiers in Neuroscience, 2019
BackgroundMany studies have reported that sevoflurane can increase neuronal apoptosis and result in cognitive deficits in rodents. Although neurotoxicity may be associated with mitochondrial dysfunction and oxidative stress, the exact mechanism remains ...
Fan Yang, Yangyang Shan, Zhiyin Tang, Xiuying Wu, Congjie Bi, Yongfang Zhang, Yan Gao, Hongtao Liu   +7 more
doaj   +1 more source