Results 21 to 30 of about 7,183,853 (276)

Cytokine-induced killer cell/dendritic cell combined with cytokine-induced killer cell immunotherapy for treating advanced gastrointestinal cancer [PDF]

open access: yesBMC Cancer, 2020
AbstractBackgroundThis study aimed to investigate the efficacy and safety of cytokine-induced killer (CIK)/dendritic cell combined with CIK (DC–CIK) cell therapy in advanced gastrointestinal cancer (GIC).MethodsThe PubMed, Cochrane library, and Embase were searched to conduct a meta-analysis of clinical controlled trials to evaluate the efficacy and ...
Hansong Du, Jia Yang, Ying Zhang
openaire   +3 more sources

Novel IL-15 dendritic cells have a potent immunomodulatory effect in immunotherapy of multiple myeloma

open access: yesTranslational Oncology, 2022
Dendritic cells (DCs) are the most potent antigen-presenting cells, and have thus been used in clinical cancer vaccines. However, the effects of DC vaccines are still limited, leading researchers to explore novel ways to make them effective.
Tan-Huy Chu   +10 more
doaj   +1 more source

Adoptive Cell Therapy of Melanoma with Cytokine-induced Killer Cells [PDF]

open access: yesImmune Network, 2015
Melanoma is the most aggressive skin cancer and its incidence is gradually increasing worldwide. Patients with metastatic melanoma have a very poor prognosis (estimated 5-year survival rate of
Kim, Ji Sung   +6 more
openaire   +2 more sources

Cytokine-induced memory-like natural killer cells [PDF]

open access: yesProceedings of the National Academy of Sciences, 2009
The mammalian immune response to infection is mediated by 2 broad arms, the innate and adaptive immune systems. Innate immune cells are a first-line defense against pathogens and are thought to respond consistently to infection, regardless of previous exposure, i.e., they do not exhibit memory of prior activation.
Megan A, Cooper   +5 more
openaire   +2 more sources

A dynamic transcriptomic atlas of cytokine-induced killer cells. [PDF]

open access: yesJ Biol Chem, 2018
Several clinical immunotherapy trials with cytokine-induced killer (CIK) cells have been reported. However, molecular evidence of cell expansion, acquisition of tumor cytotoxicity, and safety of CIK cells is required before putting them to clinical use.
Meng M   +17 more
europepmc   +4 more sources

Cytokine-induced killer cells promote antitumor immunity [PDF]

open access: yesJournal of Translational Medicine, 2013
The number of immune cells, especially dendritic cells and cytotoxic tumor infiltrating lymphocytes (TIL), particularly Th1 cells, CD8 T cells, and NK cells is associated with increased survival of cancer patients. Such antitumor cellular immune responses can be greatly enhanced by adoptive transfer of activated type 1 lymphocytes.
Jiang, J, Wu, C, Lu, B
openaire   +2 more sources

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