Results 21 to 30 of about 125,935 (288)

Effect of chaetocin on renal cell carcinoma cells and cytokine-induced killer cells [PDF]

GMS German Medical Science, 2016
We examined the cytotoxic effects of chaetocin on clear cell renal cell carcinoma (ccRCC) cells and the possibility to combine the effects of chaetocin with the effects of cytokine-induced killer cells (CIK) assayed by MTT assay and FACS analysis ...
Rombo, Roman, Weiher, Hans, Schmidt-Wolf, Ingo G.H.   +2 more
doaj   +3 more sources

Cytokine-induced killer cells/dendritic cells and cytokine-induced killer cells immunotherapy for the treatment of esophageal cancer: A meta-analysis. [PDF]

Medicine (Baltimore), 2021
Abstract Objectives: This meta-analysis was designed to systematically evaluate whether autologous cytokine-induced killer cells (CIK) or dendritic cells and cytokine-induced killer cells (DC-CIK) immunotherapy combined with chemotherapy can improve the therapeutic effect and safety of chemotherapy in esophageal ...
Yuan X, Zhang AZ, Ren YL, Wang XL, Jiang CH, Yang L, Liu CX, Liang WH, Pang LJ, Gu WY, Li F, Hu JM.   +11 more
europepmc   +5 more sources

Cytokine-induced killer cell/dendritic cell combined with cytokine-induced killer cell immunotherapy for treating advanced gastrointestinal cancer [PDF]

BMC Cancer, 2020
AbstractBackgroundThis study aimed to investigate the efficacy and safety of cytokine-induced killer (CIK)/dendritic cell combined with CIK (DC–CIK) cell therapy in advanced gastrointestinal cancer (GIC).MethodsThe PubMed, Cochrane library, and Embase were searched to conduct a meta-analysis of clinical controlled trials to evaluate the efficacy and ...
Hansong Du, Jia Yang, Ying Zhang
openaire   +3 more sources

Adoptive Cell Therapy of Melanoma with Cytokine-induced Killer Cells [PDF]

Immune Network, 2015
Melanoma is the most aggressive skin cancer and its incidence is gradually increasing worldwide. Patients with metastatic melanoma have a very poor prognosis (estimated 5-year survival rate of
Kim, Ji Sung, Kim, Yong Guk, Pyo, Minji, Lee, Hong Kyung, Hong, Jin Tae, Kim, Youngsoo, Han, Sang-Bae   +6 more
openaire   +2 more sources

Cytokine-induced memory-like natural killer cells [PDF]

Proceedings of the National Academy of Sciences, 2009
The mammalian immune response to infection is mediated by 2 broad arms, the innate and adaptive immune systems. Innate immune cells are a first-line defense against pathogens and are thought to respond consistently to infection, regardless of previous exposure, i.e., they do not exhibit memory of prior activation.
Megan A, Cooper, Julie M, Elliott, Peter A, Keyel, Liping, Yang, Javier A, Carrero, Wayne M, Yokoyama   +5 more
openaire   +2 more sources

A dynamic transcriptomic atlas of cytokine-induced killer cells. [PDF]

J Biol Chem, 2018
Several clinical immunotherapy trials with cytokine-induced killer (CIK) cells have been reported. However, molecular evidence of cell expansion, acquisition of tumor cytotoxicity, and safety of CIK cells is required before putting them to clinical use.
Meng M, Li L, Li R, Wang W, Chen Y, Xie Y, Han R, Zhu K, Huang W, Yang L, Li S, Shi J, Tan W, Gao H, Zhao Y, Yang L, Tan J, Hou Z.   +17 more
europepmc   +4 more sources

Activation of human natural killer cells by Plasmodium falciparum [PDF]

, 2003
The purpose of work described in this thesis was to (i) determine the contribution of innate immune responses to the early pro-inflammatory cytokine response to Plasmodium falciparum, (ii) describe the kinetics and ...
Artavanis-Tsakonas, Katerina
core   +1 more source

Influence of Cytokines and Autologous Lymphokine-Activated Killer Cells on Leukemic Bone Marrow Cells and Colonies in AML [PDF]

, 2001
We have already shown that cytokine cocktails (IL-1 beta, IL-3, IL-6, SCF, GM-CSF) and/or lymphokine-activated killer (LAK) cells can reduce the amounts of clonal, CD34-positive mononuclear bone marrow cells (BM-MNC) in acute myeloid leukemia (AML).
Gerhartz, Helmut Heinrich, Schmetzer, Helga Maria, Braun, Susanne Walburg   +2 more
core   +1 more source

Activation of natural killer cells during microbial infections. [PDF]

, 2011
Natural killer (NK) cells are large granular lymphocytes that express a diverse array of germline encoded inhibitory and activating receptors for MHC Class I and Class I-like molecules, classical co-stimulatory ligands, and cytokines.
Riley, Eleanor M, Eleanor M Riley, Amir eHorowitz, Horowitz, Amir, Stegmann, Kerstin A, Kerstin eStegmann, Amir Horowitz, Eleanor M. Riley, Kerstin A. Stegmann   +8 more
core   +1 more source

Blockade of Immunosuppressive Cytokines Restores NK Cell Antiviral Function in Chronic Hepatitis B Virus Infection [PDF]

, 2010
NK cells are enriched in the liver, constituting around a third of intrahepatic lymphocytes. We have previously demonstrated that they upregulate the death ligand TRAIL in patients with chronic hepatitis B virus infection (CHB), allowing them to kill ...
Richard J. Gilson, Dusheiko, G., Gilson, R.J., Dunn Claire, Gilson Richard J., Peppa, D, Patrick T F Kennedy, Ellis, G., Claire Dunn, Celeste Pallant, Dunn, C., Geoffrey Dusheiko, Lorenzo Micco, Dusheiko Geoffrey, Maini Mala K., Micco, L, Ellis, G, Pooja Khanna, Maini, MK, Pallant, C., Micco Lorenzo, Khanna, P, Javaid, A., Gilson, RJ, Micco, L., Mala K Maini, Schurich, A.; id_orcid, Javaid Alia, Khanna Pooja, Schurich, A, Kennedy, P.T.F., Anna Schurich, Pallant, C, Kennedy Patrick T. F., Mala K. Maini, Khanna, P., Peppa Dimitra, Gidon Ellis, Dusheiko, G, Javaid, A, Ellis Gidon, Dimitra Peppa, Dunn, C, Patrick T. F. Kennedy, Pallant Celeste, Maini, M.K., Kennedy, PTF, Alia Javaid, Peppa, D., Schurich Anna, Richard J Gilson   +50 more
core   +1 more source