Revving up natural killer cells and cytokine-induced killer cells against hematological malignancies [PDF]
Frontiers in Immunology, 2015 Natural killer (NK) cells belong to innate immunity and exhibit cytolytic activity against infectious pathogens and tumor cells. NK-cell function is finely tuned by receptors that transduce inhibitory or activating signals, such as killer immunoglobulin ...
Gianfranco ePittari +4 more
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Biological Character of RetroNectin Activated Cytokine-Induced Killer Cells [PDF]
Journal of Immunology Research, 2016 Adoptive cell therapy (ACT) using autologous cytokine-induced killer (CIK) cells is a promising treatment for metastatic carcinomas. In this study, we investigated the impact of RetroNectin on the proliferation, phenotype alternation, cytokine secretion,
Lu Han +3 more
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Cytokine-induced killer cells are type II natural killer T cells
GMS German Medical Science, 2007 Background: Until now, cytokine-induced killer (CIK) cells were assumed to be part of the type I natural killer T (NKT) cell population, but it was not yet investigated if this is correct.
Schmidt-Wolf, Ingo G.H. +3 more
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Efficient killing of radioresistant breast cancer cells by cytokine-induced killer cells [PDF]
Tumor Biology, 2017 Recurrence of breast cancer after radiotherapy may be partly explained by the presence of radioresistant cells. Thus, it would be desirable to develop an effective therapy against radioresistant cells. In this study, we demonstrated the intense antitumor
Qingming Guo +8 more
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Cytokine-Induced Killer Cells As Pharmacological Tools for Cancer Immunotherapy [PDF]
Frontiers in Immunology, 2017 Cytokine-induced killer (CIK) cells are a heterogeneous population of effector CD3+CD56+ natural killer T cells, which can be easily expanded in vitro from peripheral blood mononuclear cells.
Xingchun Gao +11 more
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Cytokine-induced killer cells: A novel treatment for allergic airway inflammation. [PDF]
PLoS ONE, 2017 The effectiveness of cytokine-induced killer (CIK) cells for treatment of cancers has long been appreciated. Here, we report for the first time that CIK cells can be applied to treat allergic airway inflammation.
Panwadee Pluangnooch +3 more
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Cytokine Induced Killer Cells as Promising Immunotherapy for Solid Tumors [PDF]
Journal of Cancer, 2011 Cytokine-induced killer (CIK) cells are a heterogeneous subset of ex-vivo expanded T lymphocytes which present a mixed T-NK phenotype and are endowed with a MHC-unrestricted antitumor activity. The main functional properties of CIK cells may address some
Dario Sangiolo
doaj +4 more sources
Effect of chaetocin on renal cell carcinoma cells and cytokine-induced killer cells [PDF]
GMS German Medical Science, 2016 We examined the cytotoxic effects of chaetocin on clear cell renal cell carcinoma (ccRCC) cells and the possibility to combine the effects of chaetocin with the effects of cytokine-induced killer cells (CIK) assayed by MTT assay and FACS analysis ...
Rombo, Roman +2 more
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Cytokine-induced killer cells/dendritic cells and cytokine-induced killer cells immunotherapy for the treatment of esophageal cancer: A meta-analysis. [PDF]
Medicine (Baltimore), 2021 Abstract Objectives: This meta-analysis was designed to systematically evaluate whether autologous cytokine-induced killer cells (CIK) or dendritic cells and cytokine-induced killer cells (DC-CIK) immunotherapy combined with chemotherapy can improve the therapeutic effect and safety of chemotherapy in esophageal ...
Yuan X +11 more
europepmc +4 more sources
Cytokine-induced killer cell/dendritic cell combined with cytokine-induced killer cell immunotherapy for treating advanced gastrointestinal cancer [PDF]
BMC Cancer, 2020 AbstractBackgroundThis study aimed to investigate the efficacy and safety of cytokine-induced killer (CIK)/dendritic cell combined with CIK (DC–CIK) cell therapy in advanced gastrointestinal cancer (GIC).MethodsThe PubMed, Cochrane library, and Embase were searched to conduct a meta-analysis of clinical controlled trials to evaluate the efficacy and ...
Hansong Du, Jia Yang, Ying Zhang
openaire +3 more sources