Results 61 to 70 of about 85,479 (195)
Bloodstream form trypanosoma brucei depend upon multiple metacaspases associated with RAB11-positive endosomes [PDF]
Trypanosoma brucei possesses five metacaspase genes. Of these, MCA2 and MCA3 are expressed only in the mammalian bloodstream form of the parasite, whereas MCA5 is expressed also in the insect procyclic form.
Ambit, Audrey+5 more
core +1 more source
PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential
ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah+2 more
wiley +1 more source
![Graphic][1] Furrows form in cells stuck in anaphase (top) but not metaphase. Burgess/ElsevierThink of cell division, and you probably imagine two phases occurring in successive order: first mitosis, then cytokinesis.
openaire +2 more sources
PEK14: A Kinesin‐4 Necessary for Male‐Derived Fertility in Arabidopsis thaliana
ABSTRACT Of the 61 kinesins annotated in Arabidopsis thaliana, many are still without assigned function. Here, we have screened an insertional mutant library of Arabidopsis pollen‐expressed kinesins for fertility defects. Insertional mutants for three kinesins showed a significant reduction in seed set.
Isabella N. Mendes+6 more
wiley +1 more source
Defects in leaf epidermis of Arabidopsis thaliana plants with CDKA;1 activity reduced in the shoot apical meristem [PDF]
In Arabidopsis thaliana, like in other dicots, the shoot epidermis originates from protodermis, the outermost cell layer of shoot apical meristem. We examined leaf epidermis in transgenic A.
Borowska-Wykret, Dorota+3 more
core +2 more sources
Dynamics of primary cilia in endothelial and mesenchymal cells throughout mouse lung development
Abstract Cilia are specialized structures found on a variety of mammalian cells, with variable roles in the transduction of mechanical and biological signals (by primary cilia, PC), as well as in the generation of fluid flow (by motile cilia). Their critical role in the establishment of a left–right axis in early development is well described, as well ...
Stephen Spurgin+8 more
wiley +1 more source
TSO1 functions in cell division during Arabidopsis flower development [PDF]
We describe an Arabidopsis mutant, tso1, which develops callus-like tissues in place of floral organs. The tso1 floral meristem lacks properly organized three cell layers, and the nuclei of these cells are irregular in size and shape.
Liu, Zhongchi+2 more
core
Abstract Background While heart function is broadly conserved across vertebrates, the cellular phenotype of muscle cells (cardiomyocytes) varies across taxa and throughout ontogeny. Emerging evidence suggests that some attributes may correlate with the capacity for spontaneous cardiomyocyte replacement following injury.
Kathy Jacyniak+4 more
wiley +1 more source
Regulation of Ace2-dependent genes requires components of the PBF complex in schizosaccharomyces pombe [PDF]
The division cycle of unicellular yeasts is completed with the activation of a cell separation program that results in the dissolution of the septum assembled during cytokinesis between the 2 daughter cells, allowing them to become independent entities ...
Alonso-Nuñez, María Luisa+4 more
core +1 more source
Lipidome changes in anthracycline‐induced cardiotoxicity (AIC). Aims Anthracyclines are key components of various chemotherapy regimens, but their clinical utility is limited by severe cardiotoxic side effects. Previous studies have suggested that anthracycline‐induced cardiotoxicity (AIC) may be driven by alterations in myocardial lipid metabolism ...
Vera M. Braun+6 more
wiley +1 more source