Results 21 to 30 of about 22,691 (239)

Cytoprotective–Antioxidant Effect of Brunfelsia grandiflora Extract on Neuron-like Cells

open access: yesApplied Sciences, 2023
Brunfelsia grandiflora is a South American solanaceae widely used since long ago for its recognized medicinal properties. We have recently reported its chemical composition, showing a relevant number of bioactive compounds with antioxidant capacity, and ...
José-Luis Rodríguez   +9 more
doaj   +1 more source

Cytoprotective activity of extracts from Adelia ricinella L. aerial parts. [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2021
Context: Several factors can affect the erythrocyte cell membrane integrity targeting important hematological alterations that can be avoided by the cytoprotective effect offered by some plant extracts. Aims: To evaluate the cytoprotective activity of
Clara A. Berenguer-Rivas   +7 more
doaj  

Nature-Inspired Hybrids (NIH) Improve Proteostasis by Activating Nrf2-Mediated Protective Pathways in Retinal Pigment Epithelial Cells

open access: yesAntioxidants, 2022
Antioxidant systems play key roles in many elderly diseases, including age-related macular degeneration (AMD). Oxidative stress, autophagy impairment and inflammation are well-described in AMD, especially in retinal pigment epithelial (RPE) cells.
Ali Koskela   +9 more
doaj   +1 more source

Mechanisms of 11-deoxy-16, 16-dimethyl prostaglandin E₂ mediated cytoprotection

open access: yes, 2004
Treatment of renal proximal tubule epithelial LLC-PK1 cells with 11-deoxy16,16-dimethyl prostaglandin E2 (DDM-PGE2), a stable synthetic analog of PGE2, protects against the cytotoxicity of 2,3,5-tris(glutathion-S-yl)hydroquinone (TGHQ), a potent ...
Jia, Zhe, 1976-
core   +3 more sources

Robert’s Intragastric Alcohol-Induced Gastric Lesion Model as an Escalated General Peripheral and Central Syndrome, Counteracted by the Stable Gastric Pentadecapeptide BPC 157

open access: yesBiomedicines, 2021
We redefined Robert’s prototypical cytoprotection model, namely the intragastric administration of 96% alcohol in order to generate a general peripheral and central syndrome similar to that which occurs when major central or peripheral veins are occluded
Slaven Gojkovic   +23 more
doaj   +1 more source

Human erythrocytes as pharmacological biomodel of antioxidant cytoprotection for the evaluation of new therapeutic alternatives in patients with COVID-19

open access: yesMedisan, 2022
Introduction: The oxidative stress can affect the biological membranes of different cellular types in the organism, which has been evidenced in the damages to the tissues and organs of patients with COVID-19, reason why the recent investigations are ...
Yoandra Mora Tassé   +3 more
doaj  

Morphological Characteristics of the Lung during Lipopolysaccharide and Perfluorane Inhalation

open access: yesОбщая реаниматология, 2015
The use of perfluorane for the cytoprotection of lung structures in gram-negative lung infections has been inadequately studied. Objective: to experimentally reveal the pattern of morphological changes in the lung during combined inhalation of ...
A. M. Golubev   +3 more
doaj   +1 more source

Tissue-level cytoprotection

open access: yesCell Stress & Chaperones, 2000
In vitro and ex vivo tissue models provide a useful level of biological organization for cytoprotection studies positioned between cultured cells and intact animals. We have used 2 such models, primary tissue cultures of winter flounder renal secretory epithelium and ex vivo preparations of rat intestinal tissues, the latter to access the ...
L E, Hightower   +7 more
openaire   +3 more sources

THE CHANGES OF THE ELECTROPHYSIOLOGICAL PROPERTIES OF NEURONS BY THE ACTION OF SEVOFLURANE AND THEIR ROLE IN THE MECHANISMS OF PRECONDITIONING AND CYTOPROTECTION

open access: yesВестник анестезиологии и реаниматологии, 2017
The changes of the intracellular potentials by the action of sevoflurane were studied for the diagnostic intact neurons of the isolated cerebrospinal axis of the Planorbarius corneus using intracellular electrodes.
A. I. Vislobokov   +3 more
doaj   +1 more source

Liver cytoprotection by prostaglandins

open access: yesPharmacology & Therapeutics, 1993
During the last decade intensive work on the relationships between the liver and the arachidonic acid cascade has greatly expanded our knowledge of this area of research. The liver has emerged as the major organ participating in the degradation and elimination of arachidonate products of systemic origin.
Quiroga, Jorge, Prieto, Jesus
openaire   +2 more sources

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