Results 21 to 30 of about 17,887 (202)

Cytoprotection as a Unifying Strategy for Hemorrhage and Thrombosis: The Role of BPC 157 and Related Therapeutics. [PDF]

open access: yesPharmaceuticals (Basel)
This review presents an innovative and timely exploration of how cytoprotection can serve as a cohesive therapeutic approach by which to address the hemorrhage–thrombosis paradox.
Sikiric P   +23 more
europepmc   +2 more sources

Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death

open access: yeseLife, 2022
First recognized more than 30 years ago, glycine protects cells against rupture from diverse types of injury. This robust and widely observed effect has been speculated to target a late downstream process common to multiple modes of tissue injury.
Jazlyn P Borges   +11 more
doaj   +1 more source

Pyruvate protects cerebellar granular cells from 6-hydroxydopamine-induced cytotoxicity by activating the Akt signaling pathway and increasing glutathione peroxidase expression

open access: yesNeurobiology of Disease, 2006
Parkinson disease (PD) is the second-most common age-related neurodegenerative disease and is characterized by the selective destruction of dopaminergic neurons. Increasing evidence indicates that oxidative stress plays a crucial role in the pathogenesis
F.J. Fernandez-Gomez   +9 more
doaj   +1 more source

Cytoprotective–Antioxidant Effect of Brunfelsia grandiflora Extract on Neuron-like Cells

open access: yesApplied Sciences, 2023
Brunfelsia grandiflora is a South American solanaceae widely used since long ago for its recognized medicinal properties. We have recently reported its chemical composition, showing a relevant number of bioactive compounds with antioxidant capacity, and ...
José-Luis Rodríguez   +9 more
doaj   +1 more source

Cytoprotective activity of extracts from Adelia ricinella L. aerial parts. [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2021
Context: Several factors can affect the erythrocyte cell membrane integrity targeting important hematological alterations that can be avoided by the cytoprotective effect offered by some plant extracts. Aims: To evaluate the cytoprotective activity of
Clara A. Berenguer-Rivas   +7 more
doaj  

Nature-Inspired Hybrids (NIH) Improve Proteostasis by Activating Nrf2-Mediated Protective Pathways in Retinal Pigment Epithelial Cells

open access: yesAntioxidants, 2022
Antioxidant systems play key roles in many elderly diseases, including age-related macular degeneration (AMD). Oxidative stress, autophagy impairment and inflammation are well-described in AMD, especially in retinal pigment epithelial (RPE) cells.
Ali Koskela   +9 more
doaj   +1 more source

The Role of Mcl-1 in S. aureus-Induced Cytoprotection of Infected Macrophages

open access: yesMediators of Inflammation, 2013
As a facultative intracellular pathogen, Staphylococcus aureus invades macrophages and then promotes the cytoprotection of infected cells thus stabilizing safe niche for silent persistence.
Joanna Koziel   +7 more
doaj   +1 more source

Human erythrocytes as pharmacological biomodel of antioxidant cytoprotection for the evaluation of new therapeutic alternatives in patients with COVID-19

open access: yesMedisan, 2022
Introduction: The oxidative stress can affect the biological membranes of different cellular types in the organism, which has been evidenced in the damages to the tissues and organs of patients with COVID-19, reason why the recent investigations are ...
Yoandra Mora Tassé   +3 more
doaj  

Robert’s Intragastric Alcohol-Induced Gastric Lesion Model as an Escalated General Peripheral and Central Syndrome, Counteracted by the Stable Gastric Pentadecapeptide BPC 157

open access: yesBiomedicines, 2021
We redefined Robert’s prototypical cytoprotection model, namely the intragastric administration of 96% alcohol in order to generate a general peripheral and central syndrome similar to that which occurs when major central or peripheral veins are occluded
Slaven Gojkovic   +23 more
doaj   +1 more source

Morphological Characteristics of the Lung during Lipopolysaccharide and Perfluorane Inhalation

open access: yesОбщая реаниматология, 2015
The use of perfluorane for the cytoprotection of lung structures in gram-negative lung infections has been inadequately studied. Objective: to experimentally reveal the pattern of morphological changes in the lung during combined inhalation of ...
A. M. Golubev   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy