Results 21 to 30 of about 31,874 (246)
Cytoprotective–Antioxidant Effect of Brunfelsia grandiflora Extract on Neuron-like Cells
Applied Sciences, 2023 Brunfelsia grandiflora is a South American solanaceae widely used since long ago for its recognized medicinal properties. We have recently reported its chemical composition, showing a relevant number of bioactive compounds with antioxidant capacity, and ...
José-Luis Rodríguez +9 more
doaj +1 more source
Cell Stress & Chaperones, 2000 In vitro and ex vivo tissue models provide a useful level of biological organization for cytoprotection studies positioned between cultured cells and intact animals. We have used 2 such models, primary tissue cultures of winter flounder renal secretory epithelium and ex vivo preparations of rat intestinal tissues, the latter to access the ...
L E, Hightower +7 more
openaire +3 more sources
Use of Meldonium in the Treatment of Patients with Coronary Artery Disease and Concomitant Arterial Hypertension [PDF]
, 2019 Coronary artery disease (CAD) remains one of the leading causes of mortality and disability in Ukraine. Arterial hypertension (AH) is one of the most common diseases and a leading risk factor for coronary artery disease.The aim of the work is to evaluate
Vakaliuk, I. (Ihor) +1 more
core +3 more sources
Cytoprotective activity of extracts from Adelia ricinella L. aerial parts. [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2021 Context: Several factors can affect the erythrocyte cell membrane integrity targeting important hematological alterations that can be avoided by the cytoprotective effect offered by some plant extracts. Aims: To evaluate the cytoprotective activity of
Clara A. Berenguer-Rivas +7 more
doaj
Protective activity of aromatic amines and imines against oxidative nerve cell death [PDF]
, 2001 Oxidative stress is a widespread phenomenon in the pathology of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis.
Behl, Christian +3 more
core +1 more source
Innate immune receptor NOD2 mediates LGR5+ intestinal stem cell protection against ROS cytotoxicity via mitophagy stimulation [PDF]
, 2020 International audienceThe nucleotide-binding oligomerization domain-containing protein 2 (NOD2) agonist muramyl dipeptide (MDP), a peptidoglycan motif common to all bacteria, supports leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5 ...
Deutsch, Eric +6 more
core +4 more sources
Thioredoxin-1 maintains mechanistic target of rapamycin (mTOR) function during oxidative stress in cardiomyocytes [PDF]
, 2017 Thioredoxin 1 (Trx1) is a 12-kDa oxidoreductase that catalyzes thiol-disulfide exchange reactions to reduce proteins with disulfide bonds. As such, Trx1 helps protect the heart against stresses, such as ischemia and pressure overload.
Bhat, Santosh +16 more
core +1 more source
Antioxidants, 2022 Antioxidant systems play key roles in many elderly diseases, including age-related macular degeneration (AMD). Oxidative stress, autophagy impairment and inflammation are well-described in AMD, especially in retinal pigment epithelial (RPE) cells.
Ali Koskela +9 more
doaj +1 more source
The Role of Mcl-1 in S. aureus-Induced Cytoprotection of Infected Macrophages
Mediators of Inflammation, 2013 As a facultative intracellular pathogen, Staphylococcus aureus invades macrophages and then promotes the cytoprotection of infected cells thus stabilizing safe niche for silent persistence.
Joanna Koziel +7 more
doaj +1 more source
Biomedicines, 2021 We redefined Robert’s prototypical cytoprotection model, namely the intragastric administration of 96% alcohol in order to generate a general peripheral and central syndrome similar to that which occurs when major central or peripheral veins are occluded
Slaven Gojkovic +23 more
doaj +1 more source