Results 31 to 40 of about 17,887 (202)

THE CHANGES OF THE ELECTROPHYSIOLOGICAL PROPERTIES OF NEURONS BY THE ACTION OF SEVOFLURANE AND THEIR ROLE IN THE MECHANISMS OF PRECONDITIONING AND CYTOPROTECTION

open access: yesВестник анестезиологии и реаниматологии, 2017
The changes of the intracellular potentials by the action of sevoflurane were studied for the diagnostic intact neurons of the isolated cerebrospinal axis of the Planorbarius corneus using intracellular electrodes.
A. I. Vislobokov   +3 more
doaj   +1 more source

Cytoprotective Compounds Interfere with the Nutraceutical Potential of Bread Supplemented with Green Coffee Beans

open access: yesAntioxidants, 2019
The proliferation and motile activity of prostate epithelial (Pnt2) and cancer cells (DU-145; PC-3) in the presence of bioavailable compounds from green coffee beans (GCB), wholemeal wheat bread (WMWB), and its GCB-fortified variant were analyzed.
Urszula Gawlik-Dziki   +6 more
doaj   +1 more source

Dimethyl Fumarate Triggers the Antioxidant Defense System in Human Retinal Endothelial Cells through Nrf2 Activation

open access: yesAntioxidants, 2022
Dimethyl fumarate (DMF) is a well-known activator of Nrf2 (NF-E2-related factor 2), used in the treatment of psoriasis and multiple sclerosis. The mechanism of action consists in the modification of the cysteine residues on the Nrf2-inhibitor Keap1, thus
Federico Manai, Marialaura Amadio
doaj   +1 more source

Flavonoids and Mitochondria: Activation of Cytoprotective Pathways?

open access: yesMolecules, 2020
A large number of diverse mechanisms that lead to cytoprotection have been described to date. Perhaps, not surprisingly, the role of mitochondria in these phenomena is notable. In addition to being metabolic centers, due to their role in cell catabolism,
Anna Kicinska, Wieslawa Jarmuszkiewicz
doaj   +1 more source

Features of therapeutic correction of GERD: focus on cytoprotection (with a clinical case)

open access: yesМедицинский совет, 2022
Тo date, the possible links of the pathogenesis of this disease have been well studied and described, which predetermine certain approaches to the treatment of various variants of gastroesophageal reflux disease (GERD).
I. G. Pakhomova
doaj   +1 more source

Experimental Study on Cytoflavin Pharmacological Correction of Cyclophosphamide-Induced Toxic Affections of the Liver and Kidneys

open access: yesАнтибиотики и Химиотерапия, 2020
The experimental data concerning the influence of repeated administration of cyclophosphamide in a total dose of 200 mg/kg on the glutathione metabolism and lipide peroxidation in the liver and kidneys of albino noninbred rats are presented.
V. A. Kashuro   +3 more
doaj  

Can Melatonin Be a Potential “Silver Bullet” in Treating COVID-19 Patients?

open access: yesDiseases, 2020
The therapeutic potential of melatonin as a chronobiotic cytoprotective agent to counteract the consequences of COVID-19 infections has been advocated.
Daniel P. Cardinali   +2 more
doaj   +1 more source

Screening of exopolysaccharide-producing Enterobacter aerogenes NJ1023 and its cadaverine biosynthesis promotion

open access: yesFrontiers in Microbiology, 2023
Enterobacter aerogenes, the gram-negative bacteria belonging to the family Enterobacteriaceae, lacks the ability to synthesize chemicals. However, in this study, a strain of Enterobacter aerogenes NJ1023 screened from the soil containing petrochemicals ...
Yanai Xie   +6 more
doaj   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

open access: yesAdvanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda   +8 more
wiley   +1 more source

Selenium in Oncology: From Chemistry to Clinics

open access: yesMolecules, 2009
The essential trace element selenium, which is a crucial cofactor in the most important endogenous antioxidative systems of the human body, is attracting more and more the attention of both laypersons and expert groups. The interest of oncologists mainly
Oliver Micke   +4 more
doaj   +1 more source

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