Results 51 to 60 of about 254,703 (199)

Herbivory induced methylation changes in the Lombardy poplar: A comparison of results obtained by epiGBS and WGBS.

PLoS ONE, 2023
DNA cytosine methylation is an epigenetic mechanism involved in regulation of plant responses to biotic and abiotic stress and its ability to change can vary with the sequence context in which a cytosine appears (CpG, CHG, CHH, where H = Adenine, Thymine,
A Niloya Troyee, Cristian Peña-Ponton, Mónica Medrano, Koen J F Verhoeven, Conchita Alonso   +4 more
doaj   +1 more source

Transgenerational epigenetics: Inheritance of global cytosine methylation and methylation-related epigenetic markers in the shrub Lavandula latifolia

, 2018
Premise of the Study: The ecological and evolutionary significance of natural epigenetic variation (i.e., not based on DNA sequence variants) variation will depend critically on whether epigenetic states are transmitted from parents to offspring, but ...
Herrera, Carlos M., Alonso, Conchita, Bazaga, Pilar, Mónica Medrano, Pilar Bazaga, Conchita Alonso, Ricardo Pérez, Pérez, Ricardo, Carlos M. Herrera, Medrano, Mónica   +9 more
core   +1 more source

Expression in mammalian cells of a cloned gene encoding murine DNA methyltransferase [PDF]

, 1991
Mammalian DNA cytosine-5-methyltransferase (MTase, EC 2.1.1.37) is an essential component for establishing and maintaining cell-type specific methylation patterns in the genome. The cDNAfor the murine enzyme was previously cloned in segments.
Häuselmann, Remo, Bestor, Timothy H., Bestor, T. H., Page, A. W., Page, Andrea W., Hergersberg, M., Leonhardt, Heinrich, Häuselmann, R., Czank, A., Czank, Andreas, Schaffner, Walter, Schaffner, W., Hergersberg, Martin, Leonhardt, H., Bestor TH, Häuselmann R, Czank A, Page AW, Leonhardt H, Schaffner W, Hergersberg M   +20 more
core   +1 more source

CpG-methylation regulates a class of Epstein-Barr virus promoters. [PDF]

, 2010
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian gene regulation. In general, cytosine-phosphatidyl-guanosine (CpG)-methylated promoters are transcriptionally repressed and nuclear proteins such as ...
Benet-Pagès, Anna, Christine Göbel, Göbel, C., Hammerschmidt, W., Wolfgang Hammerschmidt, Schmeinck Anne, Benet-Pagès Anna, Bergbauer Martin, Schmeinck, A., Eck Sebastian, Rothbauer, Ulrich, Strom, Tim M., Hammerschmidt, Wolfgang, Bergbauer, M., Kalla, M., Sebastian Eck, Rothbauer, U., Schmeinck, Anne, Bergbauer, Martin, Göbel Christine, Tim M. Strom, Göbel, Christine, Tim M Strom, Strom Tim M., Eck, Sebastian, Anne Schmeinck, Eck, S., Martin Bergbauer, Benet-Pagès, A., Kalla, Markus, Hammerschmidt Wolfgang, Rothbauer Ulrich, Strom, T.M., Markus Kalla, Ulrich Rothbauer, Kalla Markus, Anna Benet-Pagès   +36 more
core   +2 more sources

NSun2-Mediated Cytosine-5 Methylation of Vault Noncoding RNA Determines Its Processing into Regulatory Small RNAs

Cell Reports, 2013
Autosomal-recessive loss of the NSUN2 gene has been identified as a causative link to intellectual disability disorders in humans. NSun2 is an RNA methyltransferase modifying cytosine-5 in transfer RNAs (tRNAs), yet the identification of cytosine ...
Shobbir Hussain, Abdulrahim A. Sajini, Sandra Blanco, Sabine Dietmann, Patrick Lombard, Yoichiro Sugimoto, Maike Paramor, Joseph G. Gleeson, Duncan T. Odom, Jernej Ule, Michaela Frye   +10 more
doaj   +1 more source

A Molecular Cloning and Sanger Sequencing-based Protocol for Detecting Site-specific DNA Methylation

Bio-Protocol, 2022
DNA methylation is a conserved chemical modification, by which methyl groups are added to the cytosine of DNA molecules. Methylation can influence gene expression without changing the sequence of a particular gene. This epigenetic effect is an intriguing
Wei Guo, Anthony Cannon , Damon Lisch
doaj   +1 more source

Turnover and function of DNA methylation at transcription factor binding sites [PDF]

, 2014
Cell type identity is largely determined by regulatory networks consistent of various transcription factors. Transcription factor activity requires interaction with DNA and thus critically depends on the accessibility of binding motifs.
Feldmann, Angelika
core   +1 more source

Transcription influences repair-induced DNA methylation [PDF]

, 2008
This work is aimed at the dissection of the molecular mechanism(s) linking DNA damage and gene silencing. To this end, we have developed a genetic system that allows a rapid assessment of homologous-directed repair (HR) of an unique DNA double strand ...
Morano, Annalisa
core   +1 more source

The DNA cytosine methylome revealed two methylation motifs in the upstream regions of genes related to morphological and physiological differentiation in Streptomyces coelicolor A(3)2 M145

Scientific Reports, 2023
DNA methylation is an epigenetic modification detected in both prokaryotic and eukaryotic genomic DNAs. In bacteria, the importance of 5-methylcytosine (m5C) in gene expression has been less investigated than in eukaryotic systems.
Annalisa Pisciotta, Alessia Maria Sampino, Alessandro Presentato, Marco Galardini, Angel Manteca, Rosa Alduina   +5 more
doaj   +1 more source

Cytosine methylation levels at CG, CHG, and CHH and total cytosine sites in WT and msa1-1.

, 2016
Cytosine methylation levels at CG, CHG, and CHH and total cytosine sites in WT and msa1-1.
Brian Dilkes (376800), Sanja Roje (2360476), Rüdiger Hell (157848), John Danku (88325), Anna Koprivova (157792), Dai-Yin Chao (137093), Stanislav Kopriva (62918), Francisco J. Sandoval (2360479), David E Salt (32009), Xin-Yuan Huang (2203642), Steffen Müller (152855), Markus Wirtz (157805), Hermann Bauwe (143130)   +12 more
core   +1 more source