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2023
Natural products have formed the basis of traditional medicine systems throughout human history. Today, drug discovery studies from natural origins continue rapidly and efficiently with modern methods. Among the many activities, cytotoxic activity is related to the behaviour of test material on cell viability and cellular growth.
Esra Emerce, Kevser Taban Akça
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Natural products have formed the basis of traditional medicine systems throughout human history. Today, drug discovery studies from natural origins continue rapidly and efficiently with modern methods. Among the many activities, cytotoxic activity is related to the behaviour of test material on cell viability and cellular growth.
Esra Emerce, Kevser Taban Akça
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Lymphomas with cytotoxic activity
Nature, 1979TUMOURS of antibody-secreting B lymphocytes (myeloma tumours) have contributed greatly to our understanding of antibody structure and function. T-lymphocyte tumours that retain effector activities might, if they exist, prove to be similarly useful for analysing T cells and their key components.
Chang, T W, Eisen, H N
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Cytotoxic Activity of Amaryllidaceae Alkaloids
Planta Medica, 199525 Amaryllidaceae alkaloids belonging to different skeletal types were evaluated for their cytotoxic activity against one murine non-tumoral cell line (LMTK) and two human tumoral cell lines (Molt4 and HepG2) according to established protocols. Significant differences of activity related with the type of skeleton of the tested alkaloids could be ...
B, Weniger +7 more
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Cytotoxic activity of Staphylococcus hyicus
Veterinary Microbiology, 1991Culture supernatants from a number of Staphylococcus hyicus strains caused toxic effects to both murine fibroblast and porcine keratinocyte cells in culture. The extent of cytotoxicity was shown to differ between strains and may provide an indication of strain virulence. Purification of cytotoxic activity produced by S.
R P, Allaker, M, Whitlock, D H, Lloyd
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Activation of NK cell cytotoxicity
Molecular Immunology, 2005Natural killer (NK) cells are innate effector lymphocytes necessary for defence against stressed, microbe-infected, or malignant cells. NK cells kill target cells by either of two major mechanisms that require direct contact between NK cells and target cells.
Smyth, Mark J. +9 more
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Cytotoxic activities of fish leucocytes
Fish & Shellfish Immunology, 2006Like mammalian leucocytes, white blood cells of fish are able to kill altered (e.g. virus-infected) and foreign (allogeneic or xenogeneic) cells. The existence of natural killer (NK)-like and specific cytotoxic cells in fish was first shown using allogeneic and xenogeneic effector/target cell systems.
Uwe, Fischer +5 more
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Cytotoxic activities of Stachys species
Fitoterapia, 2008The cytotoxic activity of Stachys plants and of aucubin and harpagide against MCF7-breast adenocarcinoma, HeLa-cervix adenocarcinoma, A431-skin carcinoma of epithelial origin is reported in this study. Cisplatin and doxorubicin were use as reference compound.
Háznagyné Radnai Erzsébet +7 more
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Specific tumoricidal activity of cytotoxic macrophages and cytotoxic lymphocytes
Cancer Immunology, Immunotherapy, 1986The antitumor potency and specificity of syngeneic immune peritoneal exudate cells were tested. Groups of DBA/2 mice were immunized against syngeneic SL2 tumor cells. Then 6 days after the last immunization the antitumor potency, and the specificity of the immunization reaction was tested by injecting groups of the immunized mice with 10(3) to 5 X 10(7)
H F, Dullens +5 more
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Cytotoxic Activity of Lymphocytes
The Journal of Immunology, 1978Abstract To detect the cellular origins of α-lymphotoxin (α-LT), we cultured various subpopulations of human blood lymphocytes separated by erythrocyte-rosetting techniques with various mitogens. T cell-enriched subpopulations responded to PHA by increased 3H-thymidine uptake into DNA and large amounts of α-LT production.
Keisuke Yano, Zoltan J Lucas
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Immunomodulatory and cytotoxic activities of euphol
Life Sciences, 2021This study evaluated the effect of euphol isolated from Euphorbia umbellata (Pax) Bruyns latex on the activation of complement pathways (classical (CP), alternative (AP) and lectin (LP)), neutrophil chemotaxis, cytotoxic activity, cell morphology and death in HRT-18 and 3T3 cells lines.CP and AP were assessed using hemolytic assays and ELISA for LP ...
Thais Latansio, de Oliveira +7 more
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