Results 221 to 230 of about 390,147 (250)

Partial role of TLR4 as a receptor responding to damage-associated molecular pattern

Immunology Letters, 2009
Part of pathogen-associated molecular pattern (PAMP) and damage-associated molecular pattern (DAMP) activate antigen-presenting cells through Toll-like receptors (TLRs) to initiate immune responses. However, controversy remains if TLR4 mediates DAMP signaling due to the confounding effects of potential LPS contamination.
Kyung-Mi Lee, Seung-Yong Seong
exaly   +3 more sources

Damage‐associated molecular patterns and immune activation in bipolar disorder

Acta Psychiatrica Scandinavica, 2015
ObjectiveImmune activation in bipolar disorder (BD) has been frequently reported. Damage‐associated molecular patterns (DAMPs) are key players in the immune activation reaction. The aim of this study was to assess DAMP levels in drug‐free patients with BD during acute episodes.MethodSerum levels of a predetermined set of DAMPs were assessed in drug ...
L, Stertz, G R, Fries, A R, Rosa, M, Kauer-Sant'anna, P, Ferrari, A V C, Paz, C, Green, Â B M, Cunha, F, Dal-Pizzol, C, Gottfried, F, Kapczinski   +10 more
openaire   +2 more sources

Damage-associated molecular patterns and their pathological relevance in diabetes mellitus

Ageing Research Reviews, 2015
Diabetes, a group of metabolic and age-related diseases, is a major global health problem, the incidence of which has increased dramatically in recent decades. Type 1 diabetes mellitus (T1DM) is a complex, T cell-mediated autoimmune disease characterized by immune cell infiltration and chronic inflammation in the islets of Langerhans.
Shin, Jung Jae, Lee, Eun Kyung, Park, Tae Joo, Kim, Wook   +3 more
openaire   +3 more sources

Damage‐Associated Molecular Patterns in the Course of Lung Cancer – A Review

Scandinavian Journal of Immunology, 2015
AbstractMore than 20 years ago, the ‘danger theory’ was proposed which explains why potent immune responses with no microbial components are elicited against tissue transplants, injuries, tumours and autoimmune diseases. It states that the immune system can distinguish between dangerous and innocuous endogenous signals.
M, Łagiedo, J, Sikora, M, Kaczmarek
openaire   +2 more sources

Damage-associated molecular patterns and their receptors in upper airway pathologies

Cellular and Molecular Life Sciences, 2013
Inflammation of the nasal (rhinitis) and sinus mucosa (sinusitis) are prevalent medical conditions of the upper airways that are concurrent in many patients; hence the terminology "rhinosinusitis". The disease status is further defined to be "chronic" in case symptoms persist for more than 12 weeks without resolution.
Koen, Van Crombruggen, Fenila, Jacob, Nan, Zhang, Claus, Bachert   +3 more
openaire   +2 more sources

Preeclampsia and damage — associated molecular patterns

Rossiiskii vestnik akushera-ginekologa, 2021
V.I. Shcherbakov, I.M. Pozdnyakov, A.V. Shirinskaya   +2 more
openaire   +1 more source

[Damage-associated molecular patterns and chronic diseases].

Sheng li ke xue jin zhan [Progress in physiology], 2012
Molecules of damage-associated molecular patterns (DAMPs) are a class of substances released to intercellular space or peripheral blood by tissues or cells which are stimulated by insults, ischemia or stress. DAMP molecules can be recognized by Toll like receptors, Nod1-like receptors, or Rig-I like receptors and induce autoimmunity or immune tolerance,
Hong-Zhen, Yang, Wen-Feng, Cai, Zhuo-Wei, Hu   +2 more
openaire   +1 more source

[Damage-associated molecular patterns and liver failure].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2017
Damage-associated molecular patterns (DAMPs) are a series of intracellular molecules with immunoregulatory activity which are released by the damaged or activated cells and can induce autoimmunity or immune tolerance via pattern recognition receptors.
Y Y, Yan, S, Lin, Y Y, Zhu
openaire   +1 more source

[DAMPs (damage-associated molecular patterns) and inflammation].

Nihon rinsho. Japanese journal of clinical medicine, 2016
Post-ischemic inflammation is re-appraised as an important player in the progression of ischemic stroke. Activation of inflammatory cells via Toll-like receptor 2 (TLR2) and TLR4 is caused by several damage-associated molecular patterns (DAMPs), including high mobility group box-1 (HMGB-1) and heat shock proteins.
Hiroaki, Ooboshi, Takashi, Shichita
openaire   +1 more source

Endocytosis of the damage‐associated molecular pattern receptor PEPR1 is BAK1‐dependent

Journal of Integrative Plant Biology
ABSTRACT After cellular damage caused by wounding or pathogens, Arabidopsis thaliana endogenous elicitor peptides (Peps) are released into the apoplast, enhancing innate immunity by directly binding to the membrane‐localized leucine‐rich repeat receptor kinase PEP RECEPTOR1 (
Lucas Alves Neubus Claus, Fausto Andres Ortiz‐Morea, Shao‐Li Yang, Shweta Yekondi, Xiangyu Xu, In‐Cheol Yeo, Isabelle Vanhoutte, Nemanja Vukašinović, Qian Ma, Ive De Smet, Ping He, Libo Shan, Eugenia Russinova   +12 more
openaire   +2 more sources