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Damage-associated molecular patterns in viral infection: potential therapeutic targets

Critical Reviews in Microbiology
Frequent viral infections leading to infectious disease outbreaks have become a significant global health concern. Fully elucidating the molecular mechanisms of the immune response against viral infections is crucial for epidemic prevention and control. The innate immune response, the host's primary defense against viral infection, plays a pivotal role
Huizhen, Tian   +4 more
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DAMPs: Damage-Associated Molecular Pattern Molecules in Hemostasis

2016
This chapter explores the role of some of the key DAMPs in modulating the coagulation and fibrinolytic cascades, how they activate platelets, and modulate platelet functions. Potential mechanisms differentiating disseminated intravascular coagulation from thrombosis are discussed with an emphasis on the generation of procoagulant membrane remnants that
openaire   +1 more source

[Relationships between damage-associated molecular patterns and organ injury].

Masui. The Japanese journal of anesthesiology, 2013
Recently studies have demonstrated that cell components called damage-associated molecular patterns (DAMPs) are secreted from cells in response to inflammation and organ injury. While DAMPs are maintained within the cell under normal conditions, they are secreted in response to systemic or chronic inflammation.
Satoshi, Hagiwara, Takayuki, Noguchi
openaire   +1 more source

DNA damage and repair in age-related inflammation

Nature Reviews Immunology, 2022
Yang Zhao   +2 more
exaly  

Damage-associated molecular patterns and pathogen-associated molecular patterns in severe bacterial infections

<p dir="ltr">Community-acquired bacterial infections can range from mild to severe, including sepsis. The mechanisms driving severe disease and poor outcomes remain unclear. The early host response in sepsis is triggered by pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), which activate the innate ...
openaire   +1 more source

Female erectile tissues and sexual dysfunction after pelvic radiotherapy: A scoping review

Ca-A Cancer Journal for Clinicians, 2022
Deborah C Marshall, Mas   +2 more
exaly  

Nuclear DNA damage signalling to mitochondria in ageing

Nature Reviews Molecular Cell Biology, 2016
Evandro Fei Fang   +2 more
exaly  

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