Results 21 to 30 of about 41,481 (235)

Molecular biology of autoinflammatory diseases

Inflammation and Regeneration, 2021
The long battle between humans and various physical, chemical, and biological insults that cause cell injury (e.g., products of tissue damage, metabolites, and/or infections) have led to the evolution of various adaptive responses.
Junya Masumoto, Wei Zhou, Shinnosuke Morikawa, Sho Hosokawa, Haruka Taguchi, Toshihiro Yamamoto, Mie Kurata, Naoe Kaneko   +7 more
doaj   +1 more source

Extracellular ATP acts as a damage-associated molecular pattern (DAMP) signal in plants [PDF]

Frontiers in Plant Science, 2014
As sessile organisms, plants have evolved effective mechanisms to protect themselves from environmental stresses. Damaged (i.e., wounded) plants recognize a variety of endogenous molecules as danger signals, referred to as damage-associated molecular patterns (DAMPs).
Tanaka, Kiwamu, Choi, Jeongmin, Cao, Yangrong, Stacey, Gary   +3 more
openaire   +4 more sources

Diagnostic accuracy of damage-associated molecular patterns (DAMPs) in patients with heart failure with a reduced ejection fraction. [PDF]

J Clin Transl Sci, 2017
Hartupee J, Patel R, Staloch L, Dávila-Román VG, de las Fuentes L, Novak E, Mann DL.   +6 more
europepmc   +5 more sources

Exosomes in Sepsis

Frontiers in Immunology, 2020
Sepsis is a severe state of infection with high mortality. Pathogen-associated molecular patterns and damage-associated molecular patterns (DAMPs) initiate dysregulated systemic inflammation upon binding to pattern recognition receptors.
Atsushi Murao, Max Brenner, Max Brenner, Monowar Aziz, Ping Wang, Ping Wang, Ping Wang   +6 more
doaj   +1 more source

A damage-associated molecular patterns-related gene signature for the prediction of prognosis and immune microenvironment in children stage III acute lymphoblastic leukemia

Frontiers in Pediatrics, 2022
BackgroundImmunogenic cell death (ICD)-mediated immune response provides a strong rationale to overcome immune evasion in acute lymphoblastic leukemia (ALL). ICD will produce damage-associated molecular patterns (DAMPs) in tumor microenvironment. However,
Feng Zhao, Feng Zhao, Qiuyu Lin, Xiayu Xiang, Wei Xiang, Wei Xiang   +5 more
doaj   +1 more source

DAMPs from death to new life

Frontiers in Immunology, 2015
Our body handles tissue damage by activating the immune system in response to intracellularmolecules released by injured tissues (Damage-Associated Molecular Patterns, DAMPs), in a similar way as it detects molecular motifs conserved in pathogens ...
Emilie eVénéreau, Emilie eVénéreau, Chiara eCeriotti, Marco Emilio Bianchi, Marco Emilio Bianchi   +4 more
doaj   +1 more source

The immune suppressive properties of damage associated molecular patterns in the setting of sterile traumatic injury

Frontiers in Immunology, 2023
Associated with the development of hospital-acquired infections, major traumatic injury results in an immediate and persistent state of systemic immunosuppression, yet the underlying mechanisms are poorly understood.
Emily Horner, Janet M. Lord, Janet M. Lord, Jon Hazeldine, Jon Hazeldine   +4 more
doaj   +1 more source

Fas/CD95 Signaling Pathway in Damage-Associated Molecular Pattern (DAMP)-Sensing Receptors

Cells, 2022
Study of the initial steps of the CD95-mediated signaling pathways is a field of intense research and a long list of actors has been described in the literature. Nonetheless, the dynamism of protein-protein interactions (PPIs) occurring in the presence or absence of its natural ligand, CD95L, and the cellular distribution where these PPIs take place ...
Galli, Gael, Vacher, Pierre, Ryffel, Bernhard, Blanco, Patrick, Legembre, Patrick   +4 more
openaire   +4 more sources

Sequestering of damage-associated molecular patterns (DAMPs): a possible mechanism affecting the immune-stimulating properties of aluminium adjuvants. [PDF]

Immunol Res, 2017
Aluminium-based adjuvants (ABAs) have been used in human and veterinary vaccines for decades, and for a long time, the adjuvant properties were believed to be mediated by an antigen depot at the injection site, prolonging antigen exposure to the immune system.
Svensson A, Sandberg T, Siesjö P, Eriksson H.   +3 more
europepmc   +6 more sources

Recognition of damage-associated, nucleic acid-related molecular patterns during inflammation and vaccination

Frontiers in Cellular and Infection Microbiology, 2013
All mammalian cells are equipped with large numbers of sensors for protection from various sorts of invaders, who, in turn, are equipped with molecules containing pathogen-associated molecular patterns (PAMPs).
Nao eJounai, Nao eJounai, Kouji eKobiyama, Kouji eKobiyama, Fumihiko eTakeshita, Fumihiko eTakeshita, Ken J. Ishii, Ken J. Ishii   +7 more
doaj   +1 more source