Results 1 to 10 of about 41,332 (106)

Damage-associated molecular patterns (DAMPs) in diseases: implications for therapy [PDF]

Molecular Biomedicine
Damage-associated molecular patterns (DAMPs) are endogenous danger signal molecules released by damaged, stressed or dead cells that bind to pattern recognition receptors (PRRs), activating immune responses and inflammatory signaling pathways to play ...
Heya Lin, Wei Xiong, Lili Fu, Jie Yi, Jiantang Yang   +4 more
doaj   +3 more sources

Untangling Local Pro-Inflammatory, Reparative, and Regulatory Damage-Associated Molecular-Patterns (DAMPs) Pathways to Improve Transplant Outcomes [PDF]

Frontiers in Immunology, 2021
Detrimental inflammatory responses after solid organ transplantation are initiated when immune cells sense pathogen-associated molecular patterns (PAMPs) and certain damage-associated molecular patterns (DAMPs) released or exposed during transplant ...
Gaelen K. Dwyer, Gaelen K. Dwyer, Hēth R. Turnquist, Hēth R. Turnquist, Hēth R. Turnquist   +4 more
doaj   +4 more sources

Role of Damage-Associated Molecular Patterns (DAMPs/Alarmins) in Severe Ocular Allergic Diseases [PDF]

Cells, 2022
Severe ocular allergic diseases, such as atopic keratoconjunctivitis and vernal keratoconjunctivitis, cause severe allergic inflammation in the conjunctiva and corneal epithelial damage, resulting in visual disturbances. The involvement of damage (danger)
Ken Fukuda, Waka Ishida, Tatsuma Kishimoto, Isana Nakajima, Yusaku Miura, Tamaki Sumi, Kenji Yamashiro   +6 more
doaj   +2 more sources

Old and new damage‐associated molecular patterns (DAMPs) in autoimmune diseases

Rheumatology & Autoimmunity, 2022
All organisms living in complex environments have evolved effective mechanisms of dynamic responses to extracellular stimuli. The immune system activates when damaged or injured cells release damage‐associated molecular patterns (DAMPs).
Na Kang, Xiaohang Liu, Kabeer Haneef, Wanli Liu   +3 more
doaj   +2 more sources

Role of Damage-Associated Molecular Patterns (DAMPS) in the Postoperative Period after Colorectal Surgery [PDF]

International Journal of Molecular Sciences, 2023
Santiago Cuevas, Buitrago-Ruiz M, Esther Jumilla   +2 more
exaly   +2 more sources

Damage-Associated Molecular Patterns (DAMPs) in Retinal Disorders [PDF]

International Journal of Molecular Sciences, 2022
Shyam Chaurasia, Devesh Kumar, Binapani Mahaling   +2 more
exaly   +2 more sources

Beyond pathogens: a narrative review of the immunological nexus of damage-associated molecular patterns and inflammasome activation in sterile AECOPD [PDF]

Frontiers in Immunology
The acute exacerbation of chronic obstructive pulmonary disease (AECOPD) has traditionally been attributed to pathogen-associated molecular patterns (PAMPs); however, emerging evidence highlights the critical role of damage-associated molecular patterns (
Chenwen Peng, Chenwen Peng, Jingyan Wei, Jingyan Wei, Fengao Liang, Fengao Liang, Jianfeng Chen, Jianfeng Chen, Lei Wu, Ying Huang, Ying Huang, Zhenyan Huang, Zhenyan Huang, Chuanjian Lu   +13 more
doaj   +2 more sources

The Role of Damage-Associated Molecular Patterns (DAMPs) in Human Diseases : Part II: DAMPs as diagnostics, prognostics and therapeutics in clinical medicine [PDF]

Sultan Qaboos University Medical Journal, 2015
This article is the second part of a review that addresses the role of damage-associated molecular patterns (DAMPs) in human diseases by presenting examples of traumatic (systemic inflammatory response syndrome), cardiovascular (myocardial infarction ...
Walter G. Land
doaj   +3 more sources

Damage-associated molecular patterns (DAMPs) released after burn are associated with inflammation and monocyte activation [PDF]

Burns, 2017
Meenakshi Rani, Susannah E Nicholson, Martin G Schwacha   +2 more
exaly   +2 more sources

Mitochondrial dysfunction and damage associated molecular patterns (DAMPs) in chronic inflammatory diseases [PDF]

Mitochondrion, 2018
Charles S dela Cruz, Min-Jong Kang
exaly   +2 more sources