DAMPs from death to new life [PDF]
Frontiers in Immunology, 2015 Our body handles tissue damage by activating the immune system in response to intracellularmolecules released by injured tissues (Damage-Associated Molecular Patterns, DAMPs), in a similar way as it detects molecular motifs conserved in pathogens ...
Emilie eVénéreau +4 more
doaj +4 more sources
Old and new damage‐associated molecular patterns (DAMPs) in autoimmune diseases [PDF]
Rheumatology & Autoimmunity, 2022 All organisms living in complex environments have evolved effective mechanisms of dynamic responses to extracellular stimuli. The immune system activates when damaged or injured cells release damage‐associated molecular patterns (DAMPs).
Na Kang +3 more
doaj +2 more sources
DAMPs in Unilateral Ureteral Obstruction [PDF]
Frontiers in Immunology, 2020 Damage-associated molecular patterns (DAMPs) are released from tubular and interstitial cells in the kidney after unilateral ureteral obstruction (UUO).
Maja Wyczanska, Bärbel Lange-Sperandio
doaj +3 more sources
Identification of potential DAMPs released by necroptosis in estrogen-receptor positive breast cancer cells and their effect on macrophage differentiation [PDF]
Exploration of ImmunologyAim: Mutations in key regulators of apoptosis have necessitated exploring the alternative cell death pathways like necroptosis in breast cancer (BC).
Banita Thakur +5 more
doaj +3 more sources
Damage/Danger Associated Molecular Patterns (DAMPs) Modulate Chlamydia pecorum and C. trachomatis Serovar E Inclusion Development In Vitro. [PDF]
PLoS ONE, 2015 Persistence, more recently termed the chlamydial stress response, is a viable but non-infectious state constituting a divergence from the characteristic chlamydial biphasic developmental cycle.
Cory Ann Leonard +2 more
doaj +4 more sources
Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells [PDF]
BMC Cancer, 2020 Background Chemotherapeutics can stimulate immune antitumor response by inducing immunogenic cell death (ICD), which is activated by Damage-Associated Molecular Patterns (DAMPs) like the exposure of calreticulin (CRT) on the cell surface, the release of ...
José Ignácio Gonzalez Solari +7 more
doaj +3 more sources
Viperid Envenomation Wound Exudate Contributes to Increased Vascular Permeability via a DAMPs/TLR-4 Mediated Pathway [PDF]
Toxins, 2016 Viperid snakebite envenomation is characterized by inflammatory events including increase in vascular permeability. A copious exudate is generated in tissue injected with venom, whose proteomics analysis has provided insights into the mechanisms of venom-
Alexandra Rucavado +6 more
doaj +2 more sources
The Role of Damage-Associated Molecular Patterns (DAMPs) in Human Diseases : Part II: DAMPs as diagnostics, prognostics and therapeutics in clinical medicine [PDF]
Sultan Qaboos University Medical Journal, 2015 This article is the second part of a review that addresses the role of damage-associated molecular patterns (DAMPs) in human diseases by presenting examples of traumatic (systemic inflammatory response syndrome), cardiovascular (myocardial infarction ...
Walter G. Land
doaj +4 more sources
Regulated cell death and DAMPs as biomarkers and therapeutic targets in normothermic perfusion of transplant organs. Part 2: implementation strategies [PDF]
Frontiers in TransplantationThis Part 2 of a bipartite review commences with the delineation of a conceptual model outlining the fundamental role of injury-induced regulated cell death (RCD) in the release of DAMPs that drive innate immune responses involved in early inflammation ...
Walter G. Land +5 more
doaj +3 more sources
, 2022 Levels of the DAMPs HMGB1, HSP70 and YB-1 from LN229 cells after viral infection.
Moritz Klawitter (13177230)
core +1 more source