Results 31 to 40 of about 53,511 (293)

Priming anti-tumor immunity by radiotherapy: Dying tumor cell-derived DAMPs trigger endothelial cell activation and recruitment of myeloid cells

open access: yesOncoImmunology, 2019
The major goal of radiotherapy is the induction of tumor cell death. Additionally, radiotherapy can function as in situ cancer vaccination by exposing tumor antigens and providing adjuvants for anti-tumor immune priming. In this regard, the mode of tumor
Julia Krombach   +14 more
doaj   +1 more source

Many faces of DAMPs in cancer therapy [PDF]

open access: yes, 2013
A new concept of immunogenic cell death (ICD) has recently been proposed. The immunogenic characteristics of this cell death mode are mediated mainly by molecules called ‘damage-associated molecular patterns’ (DAMPs), most of which are recognized by ...
Aaes, Tania Love   +4 more
core   +1 more source

Purinergic signaling, DAMPs, and inflammation [PDF]

open access: yes, 2020
Danger sensing is one of the most fundamental evolutionary features enabling multicellular organisms to perceive potential threats, escape from risky situations, fight actual intruders, and repair damage.
Sarti A. C.   +2 more
core   +1 more source

DAMPs expression on MG63 cell. [PDF]

open access: yes, 2022
(a) Proportions of translocated CRT. Right panels are representative histograms showing the intensity at each time point. (b) Proportions of HSP70. Right panels are representative pseudocolor map showing fluorescent intensity of HSP70 at each time point ...
Junya Yamamoto (2259142)   +12 more
core   +1 more source

A damage-associated molecular patterns-related gene signature for the prediction of prognosis and immune microenvironment in children stage III acute lymphoblastic leukemia

open access: yesFrontiers in Pediatrics, 2022
BackgroundImmunogenic cell death (ICD)-mediated immune response provides a strong rationale to overcome immune evasion in acute lymphoblastic leukemia (ALL). ICD will produce damage-associated molecular patterns (DAMPs) in tumor microenvironment. However,
Feng Zhao   +5 more
doaj   +1 more source

Gut mucosal DAMPs in IBD: from mechanisms to therapeutic implications [PDF]

open access: yes, 2016
Endogenous damage-associated molecular patterns (DAMPs) are released during tissue damage and have increasingly recognized roles in the etiology of many human diseases.
Boyapati, RK   +7 more
core   +1 more source

DAMPs, endogenous danger signals fueling airway inflammation in COPD [PDF]

open access: yes, 2017
COPD is a severe and progressive lung disease characterized by both chronic bronchitis as well as emphysema. In the Netherlands alone every year 7,000 people die from the consequences of COPD. COPD is caused by the chronic inhalation of toxic gases, like
Pouwels, Simon; id_orcid, Pouwels, Simon
core   +5 more sources

Plant–Plant Communication: Is There a Role for Volatile Damage-Associated Molecular Patterns?

open access: yesFrontiers in Plant Science, 2020
Damage-associated molecular patterns (DAMPs) are an ancient form of tissue-derived danger or alarm signals that initiate cellular signaling cascades, which often initiate defined defense responses.
Anja K. Meents, Axel Mithöfer
doaj   +1 more source

DAMPs are a core component of the fibroblast sSASP. [PDF]

open access: yes, 2020
DAMPs are a core component of the fibroblast sSASP.
Luigi Ferrucci (150038)   +11 more
core   +1 more source

Essential Role of Host Double-Stranded DNA Released from Dying Cells by Cationic Liposomes for Mucosal Adjuvanticity

open access: yesVaccines, 2019
Infectious disease remains a substantial cause of death. To overcome this issue, mucosal vaccine systems are considered to be a promising strategy. Yet, none are approved for clinical use, except for live-attenuated mucosal vaccines, mainly owing to the ...
Rui Tada   +8 more
doaj   +1 more source

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