Results 21 to 30 of about 53,511 (293)

DAMPs, PAMPs, and LAMPs in Immunity and Sterile Inflammation. [PDF]

, 2020
Recognizing the importance of leukocyte trafficking in inflammation led to some therapeutic breakthroughs. However, many inflammatory pathologies remain without specific therapy.
Zindel, Joel, Kubes, Paul
core   +1 more source

Plant immunity by damage-associated molecular patterns (DAMPs) [PDF]

, 2022
Recognition by plant receptors of microbe-associated molecular patterns (MAMPs) and pathogenicity effectors activates immunity. However, before evolving the capacity of perceiving and responding to MAMPs and pathogenicity factors, plants, like animals ...
Giulia De Lorenzo, Felice Cervone
core   +1 more source

Tumor-related HSP70 released after cryo-thermal therapy targeted innate immune initiation in the antitumor immune response

International Journal of Hyperthermia, 2020
Purpose In our previous study, a novel cryo-thermal therapy that could stimulate the maturation of innate immune cells to subsequently activate the CD4+Th1 cell-dominated antitumor response was developed.
Jun Zhu, Yue Lou, Ping Liu, Lisa X. Xu
doaj   +1 more source

Damage-associated molecular patterns and sensing receptors based molecular subtypes in malignant pleural mesothelioma and implications for immunotherapy

Frontiers in Immunology, 2023
ObjectivesMalignant pleural mesothelioma (MPM) is characterized as an incredibly aggressive form of cancer with a dismal diagnosis and a dearth of specific biomarkers and therapeutic options.
Zheng Liu, Rui Wan, Hua Bai, Jie Wang
doaj   +1 more source

Serum levels of DAMPs in compensated and decompensated liver disease. [PDF]

, 2022
Serum levels of DAMPs in compensated and decompensated liver disease.
Martin Walter Welker (12101733), Christian Markus Lange (6281903), Jonel Trebicka (206006), Christoph Welsch (22852), Philipp Stoffers (12101727), Eva Herrmann (139197), Sabrina Guckenbiehl (12101730), Stefan Zeuzem (22856)   +7 more
core   +1 more source

Damage-associated molecular patterns in vitiligo: igniter fuse from oxidative stress to melanocyte loss

Redox Report, 2022
Objectives The pathogenesis of vitiligo remains unclear. In this review, we comprehensively describe the role of damage associated molecular patterns (DAMPs) during vitiligo pathogenesis.Methods Published papers on vitiligo, oxidative stress and DAMPs ...
Jingying Wang, Yinghao Pan, Guangmin Wei, Hanxiao Mao, Rulan Liu, Yuanmin He   +5 more
doaj   +1 more source

Cellular Interplay as a Consequence of Inflammatory Signals Leading to Liver Fibrosis Development

Cells, 2020
Inflammation has been known to be an important driver of fibrogenesis in the liver and onset of hepatic fibrosis. It starts off as a process meant to protect the liver from further damage, but it can become the main promoter of liver fibrosis.
Simona-Rebeca Ignat, Sorina Dinescu, Anca Hermenean, Marieta Costache   +3 more
doaj   +1 more source

Role of Damage-Associated Molecular Patterns in Septic Acute Kidney Injury, From Injury to Recovery

Frontiers in Immunology, 2021
Damage-associated molecular patterns (DAMPs) are a group of immunostimulatory molecules, which take part in inflammatory response after tissue injury. Kidney-specific DAMPs include Tamm-Horsfall glycoprotein, crystals, and uromodulin, released by tubular
Pierre-Olivier Ludes, Pierre-Olivier Ludes, Charles de Roquetaillade, Charles de Roquetaillade, Benjamin Glenn Chousterman, Benjamin Glenn Chousterman, Julien Pottecher, Julien Pottecher, Alexandre Mebazaa, Alexandre Mebazaa   +9 more
doaj   +1 more source

Trial watch: dendritic cell vaccination for cancer immunotherapy

OncoImmunology, 2019
Dendritic- cells (DCs) have received considerable attention as potential targets for the development of anticancer vaccines. DC-based anticancer vaccination relies on patient-derived DCs pulsed with a source of tumor-associated antigens (TAAs) in the ...
Jenny Sprooten, Jolien Ceusters, An Coosemans, Patrizia Agostinis, Steven De Vleeschouwer, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi, Abhishek D. Garg   +8 more
doaj   +1 more source

DAMPs and RAGE Pathophysiology at the Acute Phase of Brain Injury: An Overview [PDF]

, 2021
Early or primary injury due to brain aggression, such as mechanical trauma, hemorrhage or is-chemia, triggers the release of damage-associated molecular patterns (DAMPs) in the extracellular space. Some DAMPs, such as S100B, participate in the regulation
Laurent Desmurs, Jérémy Grelier, Balança, Baptiste, Grelier, Jérémy, Desmurs, Laurent, Armand Perret-Liaudet, Perret-Liaudet, Armand, Anne-Claire Lukaszewicz, Lukaszewicz, Anne-Claire, Baptiste Balança   +9 more
core   +3 more sources