Results 51 to 60 of about 53,511 (293)

Extracellular Vesicles and DAMPs in Cancer: A Mini-Review

open access: yesFrontiers in Immunology, 2021
Certain cancer therapy has been shown to induce immunogenic cell death in cancer cells and may promote tumor progression instead. The external stress or stimuli may induce cell death and contribute toward the secretion of pro inflammatory molecules.
Nadiah Abu   +2 more
doaj   +1 more source

Logistic regression analyses of patient characteristics, routine biochemistry and DAMPs to predict acute decompensation. [PDF]

open access: yes, 2022
Logistic regression analyses of patient characteristics, routine biochemistry and DAMPs to predict acute decompensation.
Martin Walter Welker (12101733)   +7 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Danger‐associated molecular patterns ( DAMPs ) in acute lung injury [PDF]

open access: yes, 2013
Danger‐associated molecular patterns ( DAMPs ) are host‐derived molecules that can function to regulate the activation of pathogen recognition receptors ( PRRs ). These molecules play a critical role in modulating the lung injury response.
Tolle, Leslie B   +3 more
core   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Transplantation and Damage-Associated Molecular Patterns (DAMPs) [PDF]

open access: yes, 2016
Upon solid organ transplantation and during cancer immunotherapy, cellular stress responses result in the release of damage-associated molecular patterns (DAMPs).
Land, W.G.   +4 more
core   +1 more source

Quick Oscillations With Damping

open access: yesMathematische Nachrichten, 1979
AbstractA class of n‐th order (n > 1) differential equations with deviating arguments is considered and sufficient conditions are established in order that all bounded quickly oscillatory solutions (i.e. oscillatory solutions whose consecutive zeros have distance which approaches zero) tend to zero at ∞.
Philos, C. G., Staikos, V. A.
openaire   +3 more sources

The damped wave equation with singular damping

open access: yesProceedings of the American Mathematical Society, 2020
We analyze the spectral properties and peculiar behavior of solutions of a damped wave equation on a finite interval with a singular damping of the form α
Siegl, Petr   +2 more
openaire   +4 more sources

The immune suppressive properties of damage associated molecular patterns in the setting of sterile traumatic injury

open access: yesFrontiers in Immunology, 2023
Associated with the development of hospital-acquired infections, major traumatic injury results in an immediate and persistent state of systemic immunosuppression, yet the underlying mechanisms are poorly understood.
Emily Horner   +4 more
doaj   +1 more source

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