Results 51 to 60 of about 7,628 (201)

Interaction of Natural Dietary and Herbal Anionic Compounds and Flavonoids with Human Organic Anion Transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11) [PDF]

, 2013
Active components of complementary/alternative medicines and natural supplements are often anionic compounds and flavonoids. As such, organic anion transporters (OATs) may play a key role in their pharmacokinetic and pharmacological profiles, and ...
Sweet, Douglas H., Wang, Li
core   +3 more sources

Integrating mass spectrometry and systems biology for the modernization of natural medicines: From deciphering chemical complexity to holistic efficacy assessment

VIEW, EarlyView.
This review explores how mass spectrometry is transforming research in natural medicines, with Traditional Chinese medicine (TCM) as a primary exemplar. It details the application of advanced mass spectrometry in chemical analysis, the development of comprehensive quality control methods, and systematic research on the targeted mechanisms of single ...
Yudian Xu, Linlin Cao, Chenhuan Ding, Chen Wang, Yi Lai, Dan Ru, He Li, Wei Xu   +7 more
wiley   +1 more source

Effectiveness and safety of Danshen injections in treatment of cardiac failure: a network meta-analysis

Frontiers in Pharmacology
Objective: The purpose of this network meta-analysis (NMA) was to compare the therapeutic effects of various Danshen (Salvia miltiorrhiza Bunge [Lamiaceae; Salviae miltiorrhizae radix et rhizoma]) injections on heart failure to determine the optimal ...
Yuchen Song, Nan Song, Lianqun Jia, Yupeng Pei   +3 more
doaj   +1 more source

Exploration on Molecular Mechanism of Reversal Effect of Compound Danshen Tablets on Hepatic Fibrosis Based on Network Pharmacology

Applied Bionics and Biomechanics, 2022
Objective. To research the molecular mechanism of compound Danshen tablets in the treatment of hepatic fibrosis through network pharmacology. Methods. Traditional Chinese medicine systems pharmacology (TCMSP) and online Mendelian inheritance in man (OMIM)
Minling Cao, Jingyue Fan, Xiaoli Yang, Meifeng Shi, Shanshan Lin, Xiaoling Chi   +5 more
doaj   +1 more source

Potential effectiveness of traditional Chinese medicine for cardiac syndrome X (CSX): a systematic review and meta-analysis [PDF]

, 2013
BACKGROUND: Treatment of cardiac syndrome X with unknown pathological mechanism remains a big challenge for clinicians. Complementary and alternative medicine may bring a new choice for its management.
Hongcai Shang, Jia-ying Wang, Jing Chen, Jing-bo Zhai, Jing-yuan Mao, Lu Xiao, Wei Mu   +6 more
core   +1 more source

Salvia miltiorrhiza‐Derived Vesicle‐Like Nanoparticles Functionalised Hydrogel With Excellent Ability of Oxidative Stress Modulation and Anti‐Cardiomyocyte Apoptosis for Sepsis‐Induced Myocardial Injury

Plant Biotechnology Journal, EarlyView.
ABSTRACT In the process of myocardial cell structural and functional damage caused by various factors, current therapeutic strategies primarily focus on restoring myocardial blood supply, often neglecting the inherent complex microenvironment triggered by elevated reactive oxygen species (ROS) levels during myocardial injury.
Zhichao Liu, Shixiang Chen, Baomin Dou, Zhen Shen, Hao Liu, Xizhen Wang, Liyue Zhu, Yue Qiu, Zhongxi Lyu, Te Ba, Kuicheng Li, Jinhong Chen, Ningcen Li   +12 more
wiley   +1 more source

Simultaneous Determination of Seven Bioactive Constituents from Salvia miltiorrhiza in Rat Plasma by HPLC-MS/MS: Application to a Comparative Pharmacokinetic Study

Separations, 2021
The roots of Salvia miltiorrhiza (Danshen) is a precious herbal medicine used to treat cardiovascular diseases. This study establishes a high-performance liquid chromatography-tandem mass spectrometric (HPLC-MS/MS) method to quantify seven bioactive ...
Yanli Zhang, Weiliang Cui, Xianghong Liu, Ning Wang, Wenru Kong, Junyu Sui, Huifen Li, Shuqi Wang   +7 more
doaj   +1 more source

Cytochrome P450 enzyme mediated herbal drug interactions (Part 2) [PDF]

, 2014
To date, a number of significant herbal drug interactions have their origins in the alteration of cytochrome P450 (CYP) activity by various phytochemicals. Among the most noteworthy are those involving St.
Phopin, Kamonrat, Prachayasittikul, Virapong, Wanwimolruk, Sompon   +2 more
core  

Herb Target Prediction Based on Representation Learning of Symptom related Heterogeneous Network. [PDF]

, 2019
Traditional Chinese Medicine (TCM) has received increasing attention as a complementary approach or alternative to modern medicine. However, experimental methods for identifying novel targets of TCM herbs heavily relied on the current available herb ...
Chen, Jianxin, Gao, Zhuye, Hu, Xiaochen, Li, Peng, Liu, Baoyan, Peng, Yonghong, Wang, Ning, Xu, Hao, Yang, Kuo, Zhang, Runshun, Zhou, Xuezhong, Zhu, Qiang   +11 more
core   +1 more source

Synergism of Chinese Herbal Medicine: Illustrated by Danshen Compound [PDF]

Evidence-Based Complementary and Alternative Medicine, 2016
The primary therapeutic effects of Chinese herbal medicine (CHM) are based on the properties of each herb and the strategic combination of herbs in formulae. The herbal formulae are constructed according to Chinese medicine theory: the “Traditional Principles for Constructing Chinese Herbal Medicinal Formulae” and the “Principles of Combining Medicinal
Su, Xuefeng, Yao, Zhuoting, Li, Shengting, Sun, He   +3 more
openaire   +2 more sources