Results 41 to 50 of about 5,900 (176)
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia +6 more
wiley +1 more source
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley +1 more source
SUMMARY Salvia miltiorrhiza Bunge is a valuable medicinal plant, yet its genetic manipulation has been limited by the lack of efficient and practical transformation methods. Here, we report a simplified, tissue culture‐independent strategy enabling Agrobacterium‐mediated gene delivery under non‐sterile conditions, termed hypocotyl acupuncture.
Chaoyang Wang +8 more
wiley +1 more source
Antioxidant Chemistry of Phenolics in Chinese Herbal Medicines: A Holism‐Based Review
Phenolic antioxidants in CHMs mainly include chalcone, stilbene, flavonoid, xanthone, and Diels–Alder‐type adducts. They undergo direct and indirect pathways to exert antioxidant action. The indirect pathway is transition metal‐chelating, while the direct pathway comprises several redox‐based reactions (e.g., SET and HAT) and RAF reactions.
Xican Li
wiley +1 more source
Anti-Amyloidogenic Properties of Some Phenolic Compounds
A family of 21 polyphenolic compounds consisting of those found naturally in danshen and their analogues were synthesized and subsequently screened for their anti-amyloidogenic activity against the amyloid beta peptide (Aβ42) of Alzheimer’s disease ...
Afsaneh Porzoor +5 more
doaj +1 more source
Strategies for Target Identification and Mechanism Elucidation in Phytochemicals
Strategies for Target Identification of Phytochemicals: Labeling Methods VS. Non‐Labeling Methods ABSTRACT Drug targets serve as the fundamental biological basis through which phytochemicals exert their therapeutic effects, and target discovery represents both the core challenge and the rate‐limiting step in elucidating the mechanisms of action of ...
Jialing Chen +4 more
wiley +1 more source
ABSTRACT According to the traditional Chinese veterinary medicine (TCVM) theory, Yin deficiency contributes to the acute onset of eclampsia. This condition arises primarily from the substantial loss of blood and nutrients to the foetus during pregnancy, leading to insufficient nutrition and blood supply. Consequently, the muscles and veins are deprived
Shuo Yang +4 more
wiley +1 more source
Effects of Danshen injection on iron deposition in kidneys.
Representative microscopic photographs of kidneys stained with Prussian blue (magnification 400×). Samples were obtained from the control group (A), iron overload (B), DFO (C), H-Danshen (D) and L-Danshen (E) groups.
Li Chu (459196) +10 more
core +1 more source
Danshen (Salvia miltiorrhiza) is a traditional medicinal plant widely used in Asian countries for its pharmacological activities (e.g., amelioration of cardiovascular diseases).
오구택
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ABSTRACT Objectives To evaluate the status and methodological quality of randomized controlled trials published in 2024 on Chinese patent medicines and Classic Traditional Chinese Medicine Prescriptions, providing evidence for clinical practice and policy.
Xiaolei Wu +14 more
wiley +1 more source

