Results 31 to 40 of about 12,572 (254)

Salvianolic Acid B Prevents Arsenic Trioxide-Induced Cardiotoxicity In Vivo and Enhances Its Anticancer Activity In Vitro [PDF]

open access: yes, 2013
Clinical attempts to reduce the cardiotoxicity of arsenic trioxide (ATO) without compromising its anticancer activities remain to be an unresolved issue.
Chen, Rongchang   +10 more
core   +3 more sources

Clinical efficacy of Danshen preparation in the treatment of vascular cognitive impairment: A systematic review and meta-analysis

open access: yesFrontiers in Aging Neuroscience, 2023
Ethnopharmacological relevance Danshen preparations are widely used in the treatment of ischaemic cerebrovascular disease. However, the clinical efficacy of such preparations remains unclear. Consequently, Danshen preparations are used to a lesser extent
Yunze Li   +6 more
semanticscholar   +1 more source

Correlations between SmCPS1 promoter polymorphism and tanshinone contents in Salvia miltiorrhiza

open access: yesCzech Journal of Genetics and Plant Breeding, 2018
Copalyl diphosphate synthase 1 (SmCPS1) is the first committed enzyme in tanshinone biosynthesis. The promoter region plays an important role in the transcriptional regulation of genes.
Ying SUN   +5 more
doaj   +1 more source

Danshen diversity defeating dementia

open access: yesBioorganic & Medicinal Chemistry Letters, 2014
Salvia miltiorrhiza (danshen) is widely used for the clinical treatment of cerebral ischemia and cardiovascular diseases. Its diverse molecular makeup of simple and poly hydroxycinnamic acids and diterpenoid quinones are also associated with its beneficial health effects such as improved cognitive deficits in mice, protection of neuronal cells ...
Hügel, Helmut M., Jackson, Neale
openaire   +2 more sources

Compound Danshen Dripping Pill inhibits hypercholesterolemia/atherosclerosis-induced heart failure in ApoE and LDLR dual deficient mice via multiple mechanisms

open access: yesActa Pharmaceutica Sinica B, 2022
Heart failure is the leading cause of death worldwide. Compound Danshen Dripping Pill (CDDP) or CDDP combined with simvastatin has been widely used to treat patients with myocardial infarction and other cardiovascular diseases in China.
Yanfang Yang   +15 more
semanticscholar   +1 more source

A review of the biological activity and pharmacology of cryptotanshinone, an important active constituent in Danshen.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021
Cryptotanshinone (IUPAC name: (R)-1,2,6,7,8,9-hexahydro-1,6,6-trimethyl-phenanthro(1,2-b)furan-10,11-dione), a biologically active constituent extracted from the roots and rhizomes of the plant Salvia miltiorrhiza, has been studied in depth as a ...
Huayao Li   +9 more
semanticscholar   +1 more source

Preclinical and clinical examinations of Salvia miltiorrhiza and its tanshinones in ischemic conditions [PDF]

open access: yes, 2006
Salvia miltiorrhiza (Labiatae, Laminaceae), danshen, is an annual sage mainly found in China and neighboring countries. The crude drug (dried root) and its preparations are currently used in China to treat patients suffering from heart attack, angina ...
Lien Eric   +3 more
core   +1 more source

DsTRD: Danshen Transcriptional Resource Database

open access: yesPLOS ONE, 2016
Salvia miltiorrhiza has been comprehensively studied as a medicinal model plant. However, research progress on this species is significantly hindered by its unavailable genome sequences and limited number of expressed sequence tags in the National Center for Biotechnology Information database.
Yuxuan Shao   +6 more
openaire   +4 more sources

Active Hydrophilic Components of the Medicinal Herb Salvia miltiorrhiza (Danshen) Potently Inhibit Organic Anion Transporters 1 (Slc22a6) and 3 (Slc22a8) [PDF]

open access: yes, 2012
Many active components of herbal products are small organic anions, and organic anion transporters were previously demonstrated to be a potential site of drug-drug interactions.
Sweet, Douglas H., Wang, Li
core   +3 more sources

Protective Effect of Danshen Zexie Decoction Against Non-Alcoholic Fatty Liver Disease Through Inhibition of ROS/NLRP3/IL-1β Pathway by Nrf2 Signaling Activation

open access: yesFrontiers in Pharmacology, 2022
Lipid metabolism disorders are a prominent characteristic in the pathological development of non-alcoholic fatty liver disease (NAFLD). Danshen zexie decoction (DZD) is a Chinese herbal medicine that is based on zexie decoction and has an effect of ...
Yan Biao   +6 more
semanticscholar   +1 more source

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