Results 81 to 90 of about 3,123 (186)
Orchestration of Processing Body Dynamics and mRNA Decay in Arabidopsis Immunity
Cell Reports, 2019 Summary: Proper transcriptome reprogramming is critical for hosts to launch an effective defense response upon pathogen attack. How immune-related genes are regulated at the posttranscriptional level remains elusive.
Xiao Yu +8 more
doaj +1 more source
mRNA Decapping Factors LSM1 and PAT Paralogs Are Involved in Turnip Mosaic Virus Viral Infection
Molecular Plant-Microbe Interactions, 2022 Turnip mosaic virus is a devastating potyvirus infecting many economically important brassica crops. In response to this, the plant host engages its RNA silencing machinery, involving AGO proteins, as a prominent strategy to restrain turnip mosaic virus (
Zhangli Zuo +3 more
doaj +1 more source
Molecular Plant Pathology, Volume 27, Issue 5, May 2026.RSV p2 binds Lsm1, disrupting Lsm1‐Lsm4 association and impairing decapping‐dependent mRNA decay in P‐bodies, leading to the accumulation of unstable mRNAs and enhanced RSV infection. ABSTRACT Processing bodies (P‐bodies) play central roles in RNA metabolism and in the regulation of viral infection.
Anqi Hu +12 more
wiley +1 more source
Heat shock-induced accumulation of translation elongation and termination factors precedes assembly of stress granules in S. cerevisiae. [PDF]
PLoS ONE, 2013 In response to severe environmental stresses eukaryotic cells shut down translation and accumulate components of the translational machinery in stress granules (SGs).
Tomas Grousl +8 more
doaj +1 more source
Microbiology Spectrum, 2023 Some insect viruses encode suppressors of RNA interference (RNAi) to counteract the antiviral RNAi pathway. However, it is unknown whether Bombyx mori cytoplasmic polyhedrosis virus (BmCPV) encodes an RNAi suppressor. In this study, the presence of viral
Jun Pan +8 more
doaj +1 more source
“More” Artificial mRNAs: Beyond the Art of Nature
Advanced Science, Volume 13, Issue 20, 9 April 2026.Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Yuanzhe Cui +3 more
wiley +1 more source
The Plant Journal, Volume 126, Issue 1, April 2026.SUMMARY Viral diseases pose a significant threat to global apple (Malus spp.) production. While selecting appropriate rootstocks is a crucial strategy to mitigate their effects, the underlying mechanisms governing rootstock tolerance or sensitivity to viral infection at the root level remain underexplored.
Larissa Carvalho Costa +8 more
wiley +1 more source
Dcp2 phosphorylation by Ste20 modulates stress granule assembly and mRNA decay in Saccharomyces cerevisiae [PDF]
Journal of Cell Biology, 2010 Translation and messenger RNA (mRNA) degradation are important sites of gene regulation, particularly during stress where translation and mRNA degradation are reprogrammed to stabilize bulk mRNAs and to preferentially translate mRNAs required for the stress response.
Yoon, Je-Hyun, Choi, Eui-Ju, Parker, Roy
openaire +2 more sources
Coactivator regulation of active site chemistry in the mRNA decapping enzyme Dcp2 [PDF]
, 2014 Regulation of mRNA half-life is a crucial control point of gene expression. Removal of the protective 5' methylguanosine cap is a committed step in the 5'-3' decay pathway, which is carried out by the decapping enzyme Dpc2.
Aglietti, Robin
core +1 more source
The Mimivirus L375 Nudix enzyme hydrolyzes the 5' mRNA cap.
PLoS ONE, 2021 The giant Mimivirus is a member of the nucleocytoplasmic large DNA viruses (NCLDV), a group of diverse viruses that contain double-stranded DNA (dsDNA) genomes that replicate primarily in eukaryotic hosts.
Grace Kago, Susan Parrish
doaj +1 more source