Results 21 to 30 of about 34,246 (233)
Journal of Plant Interactions, 2022 The DEAD-box family has been shown to play an important role in a variety of abiotic stresses, but little is known in studies of mangrove plants. Here, the effects of cold stress on various physiological changes and the role of the DEAD-box RNA helicase ...
LuLu Hao +6 more
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DEAD-box RNA helicases in Escherichia coli [PDF]
Nucleic Acids Research, 2006 In spite of their importance in RNA metabolism, the function of DExD/H-box proteins (including DEAD-box proteins) is poorly understood at the molecular level. Here, we present recent progress achieved with the five DEAD-box proteins from Escherichia coli, which have been particularly well studied. These proteins, which have orthologues in many bacteria,
Iost, Isabelle, Dreyfus, Marc
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DEAD-box helicases: Posttranslational regulation and function [PDF]
Biochemical and Biophysical Research Communications, 2010 Helicases are enzymes that can separate duplex oligonucleotides in a NTP-dependent fashion and are essential in all aspects of DNA and RNA metabolism. Amino acid sequence analysis identified several conserved sequence motifs in DNA and RNA helicases allowing their classification into 5 major groups (Super families SF1–SF5) [1].
Eric A, Gustafson, Gary M, Wessel
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The Human RNA Helicase DDX21 Presents a Dimerization Interface Necessary for Helicase Activity
iScience, 2020 Summary: Members of the DEAD-box helicase family are involved in all fundamental processes of RNA metabolism, and as such, their malfunction is associated with various diseases.
Maria J. Marcaida +8 more
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DEAD Box Helicases in Rnp Granule [PDF]
Biophysical Journal, 2014 Processing body (p-body) granule is located at the cytoplasm of eukaryotic cells and serves as a molecular hub for collection of mRNA and RNA processing enzymes. (Science 324 pg. 26 June 2009) P-body has been implicated for mRNA storage, splicing, degradation and translational repression, but how it assembles and carries out the diverse array of ...
Kim, Younghoon +3 more
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DEAD-box helicases modulate dicing body formation in Arabidopsis [PDF]
Science Advances, 2021 RH6, RH8, and RH12 are previously unidentified D-body components and drive the formation of D-bodies through LLPSs.
Qi Li +17 more
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Frontiers in Oncology, 2021 The major obstacle to treat cervical squamous cell carcinoma (CSCC) is the high prevalence of metastasis, which severely affects 5-year survival rate and quality of life for cancer patients. The DEAD-box helicase family has been reported to be a critical
Yanhui Jiang +16 more
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DEAD-box helicase eIF4A2 inhibits CNOT7 deadenylation activity. [PDF]
Nucleic Acids Res, 2019 Abstract The CCR4–NOT complex plays an important role in the translational repression and deadenylation of mRNAs. However, little is known about the specific roles of interacting factors. We demonstrate that the DEAD-box helicases eIF4A2 and DDX6 interact directly with the MA3 and MIF domains of CNOT1 and compete for binding. Furthermore,
Meijer HA +8 more
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Structure-function analysis of DEAD-box helicase DDX43
Methods, 2022 DDX43 (DEAD-box helicase 43), also known as HAGE (helicase antigen gene), is a member of the DEAD-box protein family. It contains a K homology (KH) domain in its N terminus, a helicase core domain in its C terminus, and a flexible linker domain in between.
Ravi Shankar, Singh +5 more
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Frontiers in Plant Science, 2021 DEAD-box RNA helicases constitute the largest subfamily of RNA helicase superfamily 2 (SF2), and play crucial roles in plant growth, development, and abiotic stress responses.
Jing-Na Ru +11 more
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