Results 91 to 100 of about 243 (115)

Regulation of mammalian mRNA decapping

2011
The modulation of mRNA degradation plays a critical role for regulation of gene expression. A major mRNA decay pathway in mammals proceeding from the 5' to 3' end is initiated with shortening of 3' poly (A) tail, followed by the cleavage of the 5' cap structure (decapping) and degradation of the mRNA body by the Xrn1 exoribonuclease.
openaire   +1 more source

Biomolecular condensates amplify mRNA decapping by biasing enzyme conformation

Nature Chemical Biology, 2021
Ryan W Tibble, Anais Depaix, Joanna Kowalska   +2 more
exaly  

The TUTase URT1 connects decapping activators and prevents the accumulation of excessively deadenylated mRNAs to avoid siRNA biogenesis

Nature Communications, 2021
Hélène Scheer, Christina Piermaria, Pawel S Krawczyk   +2 more
exaly  

Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

Science, 2003
Roy Parker
exaly  

Decapping

2018
openaire   +1 more source

The highways and byways of mRNA decay

Nature Reviews Molecular Cell Biology, 2007
Nicole L Garneau, Carol J Wilusz
exaly  

In plants, decapping prevents RDR6-dependent production of small interfering RNAs from endogenous mRNAs

Nucleic Acids Research, 2015
Ángel Emilio Martínez de Alba, Ana Beatriz M Moreno, Marc Gabriel   +2 more
exaly  

Decapping

2008
openaire   +1 more source

5′-Phosphorothiolate Dinucleotide Cap Analogues: Reagents for Messenger RNA Modification and Potent Small-Molecular Inhibitors of Decapping Enzymes

Journal of the American Chemical Society, 2018
Pawel J Sikorski, Marcin Warminski, Dorota Kubacka   +2 more
exaly  

A synergistic network of interactions promotes the formation of in vitro processing bodies and protects mRNA against decapping

Nucleic Acids Research, 2017
Remco Sprangers
exaly