Results 71 to 80 of about 9,305 (205)
Wellcome Open Research, 2020 Background: Mechanisms of mRNA fate decisions play an important role in determining if a given mRNA will be translated, stored or degraded upon arrival to cytoplasm.
Nupur Bhatter +2 more
doaj +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objective Historically, performing contralateral thyroid lobectomy and lymph node dissection via the subclavian approach has been considered challenging. This study evaluated the safety and feasibility of gasless endoscopic total thyroidectomy and central compartment neck dissection via the single‐port subclavian approach (SpSCA) in comparison
Pei‐Liang Lin +7 more
wiley +1 more source
Nature Communications, 2018 The decapping enzyme Dcp2 removes the 5′ eukaryotic cap from mRNA transcripts and acts in concert with its essential activator Dcp1 and various coactivators.
Jeffrey S. Mugridge +4 more
doaj +1 more source
mRNA Decapping and 5′-3′ Decay Contribute to the Regulation of ABA Signaling in Arabidopsis thaliana
Frontiers in Plant Science, 2018 Defects in RNA processing and degradation pathways often lead to developmental abnormalities, impaired hormonal signaling and altered resistance to abiotic and biotic stress.
Izabela Wawer +5 more
doaj +1 more source
Degradation of YRA1 Pre-mRNA in the cytoplasm requires translational repression, multiple modular intronic elements, Edc3p, and Mex67p. [PDF]
PLoS Biology, 2010 Intron-containing pre-mRNAs are normally retained and processed in the nucleus but are sometimes exported to the cytoplasm and degraded by the nonsense-mediated mRNA decay (NMD) pathway as a consequence of their inclusion of intronic in-frame termination
Shuyun Dong, Allan Jacobson, Feng He
doaj +1 more source
Circular Photocaged mRNA for Light‐induced Late‐stage Activation of Translation
Angewandte Chemie International Edition, Volume 65, Issue 39, 21 September 2026.A clickable photo‐caged 5′ cap (CyCliCap) allows to make Cyclic Click Cap‐containing mRNA (CyCliCap‐mRNA) which is remarkably stable and translationally muted until irradiated, allowing for late‐stage activation of translation in cells by light. ABSTRACT mRNA is a new medical modality as vaccine and raises hopes to become a protein replacement agent ...
Bayram Terzi +6 more
wiley +1 more source
General Translational Repression by Activators of mRNA Decapping [PDF]
Cell, 2005 Translation and mRNA degradation are affected by a key transition where eukaryotic mRNAs exit translation and assemble an mRNP state that accumulates into processing bodies (P bodies), cytoplasmic sites of mRNA degradation containing non-translating mRNAs, and mRNA degradation machinery.
Coller, Jeff, Parker, Roy
openaire +2 more sources
FEBS Letters, Volume 600, Issue 17, Page 2579-2614, September 2026.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Fast Decap Allocation Based on Algebraic Multigrid [PDF]
2006 IEEE/ACM International Conference on Computer Aided Design, 2006 Decap (decoupling capacitor) is an effective technique for suppressing power supply noise. Nevertheless, over-usage of decap usually causes excessive power dissipation. Therefore, the total decap area needs to be minimized subject to power supply noise constraints.
Cheng Zhuo +3 more
openaire +1 more source
Advanced Science, Volume 13, Issue 49, 3 September 2026.This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang +10 more
wiley +1 more source