Results 81 to 90 of about 7,630 (176)
The rice protein OsFKBP20‐1b protects key RNA‐surveillance factors from breakdown, so they can better eliminate defective messages. This RNA quality‐control boost reduces errors and helps plants survive drought, revealing a link between RNA control and drought tolerance.
Haemyeong Jung +5 more
wiley +1 more source
Programmable RNA N6,2´‐O‐Dimethyladenosine Editing
ABSTRACT N6,2’‐O‐dimethyladenosine (m6Am) is a prevalent RNA modification located at the first transcribed nucleotide adjacent to the 5′ cap of mRNAs, where it has been implicated in gene regulation. However, the lack of methods for precise, transcript‐specific manipulation of m6Am has limited its functional dissection.
Yang Li +9 more
wiley +1 more source
Sensing and Filtering Environmental Fluctuations: The Case of Biomolecular Condensates in Plants
The diversity of plant condensates reflects constraints of sessile organisms to coordinate postembryonic development with environmental adaptation. This review examines how plants employ condensates to integrate temperature, light, redox, and nutrient signals.
Panagiotis N. Moschou, Dorothee Staiger
wiley +1 more source
Targeting Poxvirus Decapping Enzymes and mRNA Decay to Generate an Effective Oncolytic Virus
Through the action of two virus-encoded decapping enzymes (D9 and D10) that remove protective caps from mRNA 5′-termini, Vaccinia virus (VACV) accelerates mRNA decay and limits activation of host defenses.
Hannah Burgess +5 more
doaj +1 more source
The role of transcriptional ‘futile cycles’ in autophagy and microbial pathogenesis
Eukaryotic cells utilize macroautophagy (hereafter autophagy) to recycle cellular materials during nutrient stress. Target of rapamycin (Tor) is a central regulator of this process, acting by post-translational mechanisms, phosphorylating ...
Guowu Hu +13 more
doaj +1 more source
Andreas Schneider,1 Philipp Richard,1 Philippe Mueller,1 Christoph Jordi,1 Mary Yovanoff,2 Jakob Lange1 1Ypsomed AG, Burgdorf, Switzerland; 2Design Science, Philadelphia, PA, USACorrespondence: Jakob LangeYpsomed AG, Brunnmattstrasse 6, Burgdorf 3401 ...
Schneider A +5 more
doaj
Summary: Aging is accompanied by a pervasive collapse of proteostasis, while reducing general protein synthesis promotes longevity across taxa. Here, we show that the eIF4E isoform IFE-2 is increasingly sequestered in mRNA processing (P) bodies during ...
Matthias Rieckher +4 more
doaj +1 more source
Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs
Summary: RNA polymerase II transcripts receive a protective 5ʹ,5ʹ-triphosphate-linked 7-methylguanosine (m7G) cap, and its removal by decapping enzymes like DCP2 is critical for initiation of RNA decay.
Hao Wu +7 more
doaj +1 more source
Capping and Decapping Series of Boranes
Whereas many of the capped series of carbonyl clusters of transition metals are known, those of corresponding borane series are unknown. These include the monocapped, bicapped, tricapped, tetracapped and so on. This paper attempts to correlate selected capped series of the carbonyl series with the hypothetical corresponding ones of boranes using 14n ...
openaire +1 more source
mRNA decapping proteins regulate EIN2-dependent ethylene signaling in arabidopsis
Ethylene signaling regulates plant growth and stress adaptation through a well-defined pathway, yet its mechanistic complexity remains underexplored. Here, we identify two mRNA decapping proteins, DCP1 and DCP2, as novel regulators of canonical ethylene ...
Bai Hui Jiang +14 more
doaj +1 more source

