Results 171 to 180 of about 9,305 (205)
Some of the next articles are maybe not open access.
WIREs RNA, 2010
AbstractDecapping is a critical step in the control of mRNA stability and the regulation of gene expression. Two major decapping enzymes involved in mRNA turnover have been identified, each functioning in one of the two exonucleolytic mRNA decay pathways in eukaryotic cells.
You, Li, Megerditch, Kiledjian
openaire +2 more sources
AbstractDecapping is a critical step in the control of mRNA stability and the regulation of gene expression. Two major decapping enzymes involved in mRNA turnover have been identified, each functioning in one of the two exonucleolytic mRNA decay pathways in eukaryotic cells.
You, Li, Megerditch, Kiledjian
openaire +2 more sources
Characterization of Arabidopsis decapping proteins AtDCP1 and AtDCP2, which are essential for post-embryonic development [PDF]
FEBS Letters, 2007 Although decapping is an important process in eukaryotic mRNA turnover, little is known about this process in plants. Here, we identified Arabidopsis thaliana decapping proteins AtDCP1 and AtDCP2 and showed that (I) AtDCP2 is an active decapping enzyme, (
Hiroyasu Motose +2 more
exaly +2 more sources
Decapping the message: a beginning or an end
Biochemical Society Transactions, 2006Removal of the mRNA 5′ cap is an important step in the regulation of mRNA stability. mRNAs are degraded by at least two distinct exonucleolytic decay pathways, one from the 5′ end, and the second from the 3′ end. Two major cellular decapping enzymes have been identified, and each primarily functions in one of the two decay pathways.
H, Liu, M, Kiledjian
openaire +2 more sources
Nature Structural & Molecular Biology, 2016
The degradation of mRNAs involves removal of the 5′ protective cap via a decapping-enzyme complex, in a largely irreversible process that commits the transcript for destruction. Understanding how the decapping reaction is catalyzed and regulated are major goals in the field. New data suggest how the chemistry of decapping is controlled and orchestrated
openaire +2 more sources
The degradation of mRNAs involves removal of the 5′ protective cap via a decapping-enzyme complex, in a largely irreversible process that commits the transcript for destruction. Understanding how the decapping reaction is catalyzed and regulated are major goals in the field. New data suggest how the chemistry of decapping is controlled and orchestrated
openaire +2 more sources
2001
Publisher Summary This chapter reviews the process of mRNA decapping including the properties of a yeast decapping enzyme, encoded by the DCP1 gene, and the proteins that modulate decapping rates in vivo. In addition, the chapter also describes techniques for analyzing mRNA decapping in vitro.
T, Dunckley, R, Parker
openaire +2 more sources
Publisher Summary This chapter reviews the process of mRNA decapping including the properties of a yeast decapping enzyme, encoded by the DCP1 gene, and the proteins that modulate decapping rates in vivo. In addition, the chapter also describes techniques for analyzing mRNA decapping in vitro.
T, Dunckley, R, Parker
openaire +2 more sources
mRNA decapping activities and their biological roles
Biochimie, 1996The 5' cap structure of eukaryotic mRNAs is significant for a variety of cellular events and also serves to protect mRNAs from premature degradation. Analysis of mRNA decay in Saccharomyces cerevisiae has shown that removal of the 5' cap structure is a key step in the turnover of many yeast mRNAs, and that this decapping is carried out by Dcp1p.
Roy Parker
exaly +3 more sources
Leakage Optimized DECAP Design for FPGAs
APCCAS 2006 - 2006 IEEE Asia Pacific Conference on Circuits and Systems, 2006On-chip decoupling capacitors (Decaps) are widely used to mitigate on-chip power supply noise. At and below 100nm on-chip decaps face leakage and area overhead problems associated with it and is estimated to increase with technology scaling. A recent work has proposed a gated decap structure to reduce leakage in decaps.
Balaji Vaidyanathan +4 more
openaire +2 more sources
Developmental Effects of Decapping
Science, 2007STKE The balance between synthesis and degradation controls mRNA abundance. Goeres et al. have found that the 5′ to 3′ mRNA degradation pathway involves an mRNA decapping complex and is crucial for seedling development in Arabidopsis . The phenotypes of varicose ( vcs ) and trident ( tdt ) mutants were similar: defective leaf formation with vein ...
openaire +1 more source
Plant Science Letters, 1973
Abstract Removing the root cap of Zea mays prevents geoperception. But georeactivity may be regained after several hours. The time necessary to recover geosensitivity (GRT) is calculated using an intercept method. GRT is less for the short roots than for longer ones.
openaire +1 more source
Abstract Removing the root cap of Zea mays prevents geoperception. But georeactivity may be regained after several hours. The time necessary to recover geosensitivity (GRT) is calculated using an intercept method. GRT is less for the short roots than for longer ones.
openaire +1 more source
Science's STKE, 2007
The balance between synthesis and decay controls protein abundance at multiple levels. Goeres et al . found that a specific 5′→3′ mRNA degradation pathway involving an mRNA decapping complex was crucial for seedling development in Arabidopsis thaliana . The phenotypes of mutants in the
openaire +1 more source
The balance between synthesis and decay controls protein abundance at multiple levels. Goeres et al . found that a specific 5′→3′ mRNA degradation pathway involving an mRNA decapping complex was crucial for seedling development in Arabidopsis thaliana . The phenotypes of mutants in the
openaire +1 more source