Results 161 to 170 of about 9,305 (205)

RNA Tailing by Nucleotidyltransferases in Plants: Mechanisms, Functions, and Biological Significance. [PDF]

Plants (Basel)
Xu X, Qing X, Peng X, Chen X, Huang T, Mo B, Ren Y.   +6 more
europepmc   +1 more source

ApaH decaps Np₄N-capped RNAs in two alternative orientations. [PDF]

Nat Chem Biol
Nuthanakanti A, Korn M, Levenson-Palmer R, Wu Y, Babu NR, Huang X, Banh RS, Belasco JG, Serganov A.   +8 more
europepmc   +1 more source

Coronavirus NSP14 drives internal m7G modification to rewire host splicing and promote viral replication. [PDF]

Nucleic Acids Res
Sáenz Altamirano EE, Huang CH, Tsai YL, Tzeng TJ, Fagundes Borges Teruel N, Peñaflor-Téllez Y, Chatterjee S, Pandey I, Oswal N, Chen YG, Chang CW, Rajsbaum R, Wong LR, Corrêa IR, Hsu JC.   +14 more
europepmc   +1 more source

DDX17 and viral infection. [PDF]

Virulence
Cheng Y, Wang R, Wang A, Wu Z, Jia W, Lu H, Wu Q, Zhu S.   +7 more
europepmc   +1 more source

N7-Methylguanosine Modification in Colorectal Cancer: Molecular Insights and Clinical Implications. [PDF]

Int J Mol Sci
Zhang Q, Li C, Zhu Y, Yu M, Liu Y, Xie Y, Cao J.   +6 more
europepmc   +1 more source

Automated FLIM-FRET Segmentation Within RNP Condensates. [PDF]

Bio Protoc
Powell ND, Marcus JM, Fahim LE, Lee JE.
europepmc   +1 more source

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Monitoring mRNA Decapping Activity

Methods, 1999
mRNA decapping is a common step shared between two important mRNA decay pathways in yeast, Saccharomyces cerevisiae. To investigate how mRNAs are decapped, we have developed an assay that can be easily used to measure the decapping activity. This assay has been used to isolate yeast strains with altered decapping activities.
Stuart W Peltz, Audrey Stevens, Michael Wormington   +2 more
exaly   +3 more sources

An essential component of the decapping enzyme required for normal rates of mRNA turnover

Nature, 1996
A MAJOR pathway of messenger RNA degradation in eukaryotic cells is initiated by shortening of the poly(A) tail, which, at least in yeast, triggers a decapping reaction, thereby exposing the mRNA to 5′→ 3′ degradation1–4.
Roy Parker, Audrey Stevens
exaly   +3 more sources

mRNA decapping: finding the right structures [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2018
In eukaryotes, the elimination of the m 7 GpppN mRNA cap, a process known as decapping, is a critical, largely irreversible and highly regulated step of mRNA decay that withdraws the targeted mRNAs from the pool of translatable templates. The decapping reaction is catalysed by a multi-protein
Marc Graille, Clement Charenton
exaly   +4 more sources

Eukaryotic mRNA Decapping

Annual Review of Biochemistry, 2004
▪ Abstract  Eukaryotic mRNAs are primarily degraded by removal of the 3′ poly(A) tail, followed either by cleavage of the 5′ cap structure (decapping) and 5′->3′ exonucleolytic digestion, or by 3′ to 5′ degradation. mRNA decapping represents a critical step in turnover because this permits the degradation of the mRNA and is a site of numerous ...
Jeff, Coller, Roy, Parker
openaire   +2 more sources