Results 131 to 140 of about 29,996 (293)

Decorin Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Induces Macrophage Polarization via CD44 to Repair Hyperoxic Lung Injury

International Journal of Molecular Sciences, 2019
Bronchopulmonary dysplasia (BPD), caused by hyperoxia in newborns and infants, results in lung damage and abnormal pulmonary function. However, the current treatments for BPD are steroidal and pharmacological therapies, which cause neurodevelopmental ...
Jihye Kwon, Miyeon Kim, Y. Bae, Gee-Hye Kim, S. Choi, W. Oh, S. Um, H. Jin   +7 more
semanticscholar   +1 more source

Largely Distinct Post‐Translational Modifications Differentiate Skeletal Muscle Wasting Caused by Cancer, Dexamethasone and Aging

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Skeletal muscle wasting and weakness are prominent disease features. Originally considered to arise from common transcriptional changes, recent analyses demonstrated that different stimuli induce muscle wasting via largely distinct mRNA and protein changes.
Anna Stephan, Flavia A. Graca, Suresh Poudel, Yingxue Fu, Yong‐Dong Wang, Myriam Labelle, Fabio Demontis   +6 more
wiley   +1 more source

ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis [PDF]

, 2005
Members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family are known to influence development, angiogenesis, coagulation and progression of arthritis.
Jones, GC, Riley, GP
core   +2 more sources

Absence of the proteoglycan decorin reduces glucose tolerance in overfed male mice

Scientific Reports, 2019
Studies have implicated the extracellular matrix (ECM) of adipose tissue in insulin resistance. The proteoglycan decorin, a component of ECM, has been associated with glucose tolerance, but possible causal effects on metabolism remain to be explored.
J. Svärd, T. Røst, Camilla E. N. Sommervoll, Christine Haugen, O. Gudbrandsen, A. E. Mellgren, E. Rødahl, J. Fernø, S. Dankel, J. Sagen, G. Mellgren   +10 more
semanticscholar   +1 more source

Single Platelet Rich Plasma Glottic Injections in Vocal Pathology Demonstrate Long Term Benefits

The Laryngoscope, Volume 136, Issue 2, Page 847-853, February 2026.
Platelet rich plasma injections of the glottis result in significant voice improvements in patients with benign glottal pathology. A single injection demonstrates improvement up to 12 months in patients with vocal fold atrophy and vocal fatigue, whereas those with more severe disruption of the superficial lamina propria may require additional ...
Georgia Mackay, Camille Prigent, Jacqui Allen   +2 more
wiley   +1 more source

Stromal expression of decorin, Semaphorin6D, SPARC, Sprouty1 and Tsukushi in developing prostate and decreased levels of decorin in prostate cancer.

PLoS ONE, 2012
Background and aimDuring prostate development, mesenchymal-epithelial interactions regulate organ growth and differentiation. In adult prostate, stromal-epithelial interactions are important for tissue homeostasis and also play a significant role in ...
Alexander Henke, O Cathal Grace, George R Ashley, Grant D Stewart, Antony C P Riddick, Henry Yeun, Marie O'Donnell, Richard A Anderson, Axel A Thomson   +8 more
doaj   +1 more source

P-cadherin-induced decorin secretion is required for collagen fiber alignment and directional collective cell migration

Journal of Cell Science, 2019
Directional collective cell migration (DCCM) is crucial for morphogenesis and cancer metastasis. P-cadherin (also known as CDH3), which is a cell–cell adhesion protein expressed in carcinoma and aggressive sarcoma cells and associated with poor prognosis,
Maïlys Le Borgne-Rochet, Lucie Angevin, Elsa Bazellières, Laura Ordas, F. Comunale, E. Denisov, L. Tashireva, V. Perelmuter, I. Bièche, S. Vacher, Cédric Plutoni, M. Séveno, S. Bodin, C. Gauthier-Rouvière   +13 more
semanticscholar   +1 more source

The BosR Is Back!

Molecular Microbiology, Volume 125, Issue 2, Page 81-84, February 2026.
ABSTRACT BosR is a novel nucleic acid‐binding protein in the ferric uptake regulator (FUR) family that regulates gene expression in the Lyme disease spirochete Borrelia (Borreliella) burgdorferi. This issue of Molecular Microbiology contains a comprehensive transcriptomic study that keenly defines the regulatory swath of BosR in the vertebrate host of ...
D. Scott Samuels, Meghan C. Lybecker
wiley   +1 more source

Tenocytic induction of stem cells from bone marrow on polymeric microparticles for a new concept of tendon regenerative prosthesis [PDF]

, 2015
A new concept of a regenerative and resorbable prosthesis for tendon and ligament has been developed. The prosthesis consists of a poly-lactide acid (PLA) braid, microparticles in its interior serving as cell carriers, and a surface non-adherent coating.
Andrades-Gomez, Jose Antonio, Araque-Monrós, Mª Carmen, Becerra-Ratia, Jose, Claros, Silvia, Gil-Santos, Luis, Monleón-Pradas, Manuel, Más-Estellés, Jorge, Rodríguez-Losada, Noela   +7 more
core  

Contaminants in commercial preparations of ‘purified’ small leucine-rich proteoglycans may distort mechanistic studies [PDF]

, 2017
The authors are grateful to Genodisc (EC’s 7th Framework Programme (FP7, 2007-2013) under grant agreement no. HEALTH-F2-2008-201626) and the Orthopaedic Institute Ltd for funding.This paper reports the perplexing results that came about because of ...
Botting, Catherine H., Brown, Sharon J., Caterson, Bruce, Fuller, Heidi R., Jones, Philip, Roberts, Sally, Shirran, Sally L.   +6 more
core   +3 more sources