Results 141 to 150 of about 11,453 (186)
Increased dipeptidyl peptidase 4 in patients with concomitant transthyretin cardiac amyloidosis and severe aortic stenosis. [PDF]
Holt MF +11 more
europepmc +1 more source
Curcumin alleviates the effects of heat stress on broiler pectoral muscle via decorin (DCN) -mediated TGF-β Signaling pathway. [PDF]
Bai D, Hu Y, Liu Y, Xue M, Liu X.
europepmc +1 more source
Unmasking inflammation in juvenile dermatomyositis: myokine profiles of patients and bioengineered human muscle. [PDF]
Covert LT +6 more
europepmc +1 more source
Decorin regulates cartilage pericellular matrix micromechanobiology
In cartilage tissue engineering, one key challenge is for regenerative tissue to recapitulate the biomechanical functions of native cartilage while maintaining normal mechanosensitive activities of chondrocytes. Thus, it is imperative to discern the micromechanobiological functions of the pericellular matrix, the ~ 2-4 µm-thick domain that is in ...
Biao Han, Bryan Kwok, Su-Jin Heo
exaly +4 more sources
Selective inactivity of TGF-β/decorin complexes [PDF]
Previous studies had shown that binding of TGF‐β to the small proteoglycan decorin results in its inactivation. Indeed, in osteosarcoma cells the addition of decorin prevented the TGF‐β1‐mediated up‐regulation of biglycan synthesis. However, the down‐regulation of proteoglycan‐100 remained unaltered.
Andrej Hasilik
exaly +3 more sources
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Biosynthesis of decorin and glypican
Matrix Biology, 2000Decorin and glypican are two examples of exclusively chondroitin/dermatan sulfate and heparan sulfate-substituted proteoglycans, respectively. Decorin is a secretory product, whereas glypican is linked to membrane lipids via a glycosyl-phosphatidyl-inositol (GPI) anchor.
L A, Fransson +5 more
openaire +2 more sources
Decorin in the Tumor Microenvironment
2020The tumor microenvironment plays a determining role in cancer development through a plethora of interactions between the extracellular matrix and tumor cells. Decorin is a prototype member of the SLRP family found in a variety of tissues and is expressed in the stroma of various forms of cancer. Decorin has gained recognition for its essential roles in
Kornélia, Baghy +3 more
openaire +2 more sources

