Results 21 to 30 of about 42,453 (236)
Veterinary Immunology and Immunopathology, 2008 Modulation of defensin expression may be one way to improve animal health and to reduce zoonotic diseases. Defensins are small, cationic, and amphipathic cysteine-rich antibiotic peptides found in plants, insects, mammals and birds. Whereas alpha- and theta-defensins appear to be absent in birds, several beta-defensins have been isolated from avian ...
van Dijk, A. +2 more
openaire +4 more sources
Medicinal Potentialities of Plant Defensins: A Review with Applied Perspectives
Medicines, 2019 Plant-based secondary metabolites with medicinal potentialities such as defensins are small, cysteine-rich peptides that represent an imperative aspect of the inherent defense system.
Nida Ishaq +2 more
doaj +1 more source
Elevated Concentration of Defensins in Hepatitis C Virus-Infected Patients
Journal of Immunology Research, 2016 Hepatitis C virus (HCV) is the major etiological agent of human non-A and non-B hepatitis, affecting around 180 million people worldwide. Defensins, small cysteine-rich cationic peptides, are shown to have potent antibacterial, antiviral, and antifungal ...
Ehab H. Mattar +4 more
doaj +1 more source
Antiplasmodial activity is an ancient and conserved feature of tick defensins
Frontiers in Microbiology, 2016 Ancestral sequence reconstruction has been widely used to test evolution-based hypotheses. The genome of the European tick vector, Ixodes ricinus, encodes for defensin peptides with diverse antimicrobial activities against distantly related pathogens ...
Alejandro Cabezas-Cruz +9 more
doaj +1 more source
Cyclic Peptides as Novel Therapeutic Microbicides: Engineering of Human Defensin Mimetics
Molecules, 2017 Cyclic peptides are receiving significant attention thanks to their antimicrobial activity and high serum stability, which is useful to develop and design novel antimicrobial agents.
Annarita Falanga +6 more
doaj +1 more source
Antifungal Plant Defensins: Mechanisms of Action and Production
Molecules, 2014 Plant defensins are small, cysteine-rich peptides that possess biological activity towards a broad range of organisms. Their activity is primarily directed against fungi, but bactericidal and insecticidal actions have also been reported.
Kim Vriens +2 more
doaj +1 more source
Defensins: A Double-Edged Sword in Host Immunity
Frontiers in Immunology, 2020 Defensins are a major family of host defense peptides expressed predominantly in neutrophils and epithelial cells. Their broad antimicrobial activities and multifaceted immunomodulatory functions have been extensively studied, cementing their role in ...
Dan Xu, Wuyuan Lu
doaj +1 more source
BioMed Research International, 2014 Sepsis is a leading cause of mortality and morbidity in the critical illness. Multiple immune inflammatory processes take part in the pathogenesis of sepsis. Defensins are endogenous antimicrobial peptides with three disulphide bonds created by six cysteine residues.
Xie, Guo-Hao +3 more
openaire +2 more sources
Role of lactobacilli and lactoferrin in the mucosal cervicovaginal defense [PDF]
, 2018 Human lactoferrin is an iron-binding glycoprotein present at high concentrations in breast milk and colostrum. It is produced by many exocrine glands and widely distributed in a variety of body fluids.
Aagaard +156 more
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Reproductive Biology and Endocrinology, 2006 Background beta-defensins are small cationic peptides that exhibit broad spectrum antimicrobial properties. The majority of beta-defensins identified in humans are predominantly expressed in the male reproductive tract and have roles in non-immunological
French Frank S +5 more
doaj +1 more source