Results 181 to 190 of about 4,051 (196)

Genetic and Biochemical Approaches for Analysis of Mitochondrial Degradosome from Saccharomyces cerevisiae

2001
Publisher Summary Regulation of RNA turnover is one of the major mechanisms of controlling gene expression in yeast mitochondria. RNA degradation is carried out by the yeast mitochondrial degradosome (also known as mtEXO); a multiprotein enzyme complex showing NTP-dependent 3′ → 5′-exoribonuclease activity in vitro.
A, Dziembowski, P P, Stepien
openaire   +2 more sources

Structural Studies of the Yeast Mitochondrial Degradosome

2005
The yeast mitochondrial degradosome/exosome (mtExo) is responsible for most RNA turnover in mitochondria and has been proposed to form a central part of a mitochondrial RNA surveillance system responsible for degradation of aberrant and unprocessed RNA ([1], [2]).
Feddersen, Ane, Jonstrup, Anette Thyssen, Brodersen, Ditlev Egeskov   +2 more
openaire   +2 more sources

Composition and adpatation of the E. coli RNA degradosome

2004
Although transcription and translation are recognized mechanisms for regulating gene expression, control over RNA stability can also accomplish this task. In E. coli, bulk mRNA degradation is largely carried out by a complex of enzymes called the degradosome. It is composed of the endonuclease RNase E, the exonuclease PNPase, the helicase RhIB, and the
openaire   +1 more source

Towards Understanding Helicase and Chaperone Activities in the RNA Degradosome

2020
The E. coli RNA degradosome is a complex multi-enzyme machine which is central to the post-transcriptional regulation of the cell. Some of its functions include maturing and processing sRNA, rRNA, and tRNA, as well as degrading mRNA. The key components of the RNA degradosome include the endoribonuclease RNase E, the DEAD-box RNA helicase RhlB, the ...
openaire   +1 more source

A proteomic approach to the analysis of RNA degradosome composition in Escherichia coli.

Methods in enzymology, 2008
The RNA degradosome is a bacterial protein machine devoted to RNA degradation and processing. In Escherichia coli, it is typically composed of the endoribonuclease RNase E, which also serves as a scaffold for the other components: the exoribonuclease PNPase, the RNA helicase RhlB, and enolase.
P. Mauri, G. Dehò
openaire   +3 more sources

Assays of the Helicase, ATPase, and Exoribonuclease Activities of the Yeast Mitochondrial Degradosome

2009
The mitochondrial degradosome (mtEXO) is the main enzymatic complex in RNA degradation, processing, and surveillance in Saccharomyces cerevisiae mitochondria. It consists of two nuclear-encoded subunits: the ATP-dependent RNA helicase Suv3p and the 3' to 5' exoribonuclease Dss1p. The two subunits depend on each other for their activity; the complex can
Michal, Malecki, Piotr P, Stepien, Pawel, Golik   +2 more
openaire   +2 more sources

Degradosome

2008
openaire   +1 more source

Studies of the RNA Degradosome-organizing Domain of the Escherichia coli Ribonuclease RNase E

Journal of Molecular Biology, 2004
Anastasia J Callaghan, Ben F Luisi, Leopold L Ilag   +2 more
exaly  

223 Involvement of the degradosome in familial vitiligo

Journal of Investigative Dermatology
E Sharoni, N Keller Rosenthal, O Sarig, K Malovitski, R Gilon, N Astman, L Samuelov, E Sprecher, M Pavlovsky   +8 more
openaire   +1 more source

Global analysis of Escherichia coli RNA degradosome function using DNA microarrays

Proceedings of the National Academy of Sciences of the United States of America, 2004
Sue Lin-Chao
exaly