Results 31 to 40 of about 2,784 (175)
Crystal structure of the Escherichia coli RNA degradosome component enolase [PDF]
Journal of Molecular Biology, 2001 The crystal structure of Escherichia coli enolase (EC 4.2.1.11, phosphopyruvate hydratase), which is a component of the RNA degradosome, has been determined at 2.5 A. There are four molecules in the asymmetric unit of the C2 cell, and in one of the molecules, flexible loops close onto the active site.
Kühnel, K., Luisi, B.
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Unraveling new roles for minor components of the E. coli RNA degradosome [PDF]
RNA Biology, 2009 Endoribonuclease E, 3'-5' exoribonuclease polynucleotide phosphorylase, RhlB RNA helicase and enolase form a multienzyme complex (the "degradosome") playing an important role in RNA processing and decay in Escherichia coli. Although a number of proteins that occasionally co-purify with the E.
Vladimir R. Kaberdin, Sue Lin‐Chao
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Distinct co-evolution patterns of genes associated to DNA polymerase III DnaE and PolC
BMC Genomics, 2012 Background Bacterial genomes displaying a strong bias between the leading and the lagging strand of DNA replication encode two DNA polymerases III, DnaE and PolC, rather than a single one.
Engelen Stefan +3 more
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Frontiers in Cellular and Infection Microbiology, 2013 Microbes are incessantly challenged by both biotic and abiotic stressors threatening their existence. Therefore, bacterial pathogens must possess mechanisms to successfully subvert host immune defenses as well as overcome the stress associated with host ...
Jason A. Rosenzweig, Ashok K Chopra
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LEVELNET to visualize, explore, and compare protein–protein interaction networks
PROTEOMICS, Volume 23, Issue 17, September 2023., 2023 Abstract Physical interactions between proteins are central to all biological processes. Yet, the current knowledge of who interacts with whom in the cell and in what manner relies on partial, noisy, and highly heterogeneous data. Thus, there is a need for methods comprehensively describing and organizing such data.
Yasser Mohseni Behbahani +4 more
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Caught in the act—Visualizing ribonucleases during eukaryotic ribosome assembly
WIREs RNA, Volume 14, Issue 4, July/August 2023., 2023 Ribonucleolytic processing of precursor ribosomal RNAs is an essential aspect of ribosome production. Structural snapshots of pre‐ribosomal particles provide new insights into how ribonuclease activities are regulated spatially and temporally during ribosome assembly.
Claudia Schneider, Katherine E. Bohnsack
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RNA components of Escherichia coli degradosome: Evidence for rRNA decay [PDF]
Proceedings of the National Academy of Sciences, 1998 Recently, we found that a multicomponent ribonucleolytic degradosome complex formed around RNase E, a key mRNA-degrading and 9S RNA-processing enzyme, contains RNA in addition to its protein components. Herein we show that the RNA found in the degradosome consists primarily of rRNA fragments that have a range of distinctive sizes.
Bessarab, DA +4 more
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Localization of components of the RNA-degrading machine in Bacillus subtilis
Frontiers in Microbiology, 2016 In bacteria, the control of mRNA stability is crucial to allow rapid adaptation to changing conditions. In most bacteria, RNA degradation is catalyzed by the RNA degradosome, a protein complex composed of endo- and exoribonucleases, RNA helicases and ...
Nora Cascante-Estepa +2 more
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Nature Communications, 2023 Ribonucleases (RNases) are responsible for RNA metabolism. RNase J, the core enzyme of the RNA degradosome, plays an essential role in global mRNA decay.
Luyao Bao +15 more
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Allosteric activation of RhlB by RNase E induces partial duplex opening in substrate RNA
Frontiers in Molecular Biosciences, 2023 The E. coli DEAD-Box helicase RhlB is responsible for ATP-dependent unwinding of structured mRNA to facilitate RNA degradation by the protein complex degradosome.
Heidi Zetzsche +2 more
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