Results 1 to 10 of about 116,525 (341)

Caffeic Acid Inhibits Degranulation, Cytokine Secretions, and <i>IP3 Receptor 2</i> Gene Expression in Compound 48/80-Stimulated Mouse P815 Mast Cells. [PDF]

Int J Mol Sci
Chang KC, Lin JY.
europepmc   +2 more sources

Anti-Inflammatory and Antimicrobial Volatile Oils: Fennel and Cumin Inhibit Neutrophilic Inflammation via Regulating Calcium and MAPKs

Frontiers in Pharmacology, 2021
Neutrophilic inflammatory diseases, such as chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS), or psoriasis, exert a huge burden on the global health system due to the lack of safe and effective treatments. Volatile
Michal Korinek, Michal Korinek, Michal Korinek, Heba Handoussa, Yi-Hong Tsai, You-Ying Chen, Meng-Hua Chen, Zan-Wei Chiou, Yu Fang, Fang-Rong Chang, Chia-Hung Yen, Chung-Fan Hsieh, Bing-Hung Chen, Mohamed El-Shazly, Mohamed El-Shazly, Tsong-Long Hwang, Tsong-Long Hwang, Tsong-Long Hwang, Tsong-Long Hwang   +18 more
doaj   +1 more source

Age-related decline in the resistance of mice to bacterial infection and in LPS/TLR4 pathway-dependent neutrophil responses

Frontiers in Immunology, 2022
Host defense against bacterial and fungal infections diminishes with age. In humans, impaired neutrophil responses are thought to contribute to this decline. However, it remains unclear whether neutrophil responses are also impaired in old mice. Here, we
Kirsti Hornigold, Julia Y. Chu, Stephen A. Chetwynd, Polly A. Machin, Laraine Crossland, Chiara Pantarelli, Karen E. Anderson, Phillip T. Hawkins, Anne Segonds-Pichon, David Oxley, Heidi C. E. Welch   +10 more
doaj   +1 more source

Mast cell distribution around the needle tract following acupuncture in Zusanli (ST36) acupoint in rats [PDF]

Bulgarian Journal of Veterinary Medicine, 2019
The aim of this study was to investigate mast cell (MCs) distribution in the vicinity of the needle tract formed after acupuncture in Zusanli (ST36) acupoint in rats.
N. D. Dimitrov, D. Y. Atanasova, N. S. Tomov, Y. A. Staykova-Pirovska, I. G. Ivanova , D. P. Sivrev   +5 more
doaj   +1 more source

Myeloid-Specific Pyruvate-Kinase-Type-M2-Deficient Mice Are Resistant to Acute Lung Injury

Biomedicines, 2022
Infiltration of polymorphonuclear neutrophils (PMNs) plays a central role in acute lung injury (ALI). The mechanisms governing PMN inflammatory responses, however, remain incompletely understood.
Xinlei Sun, Fujie Shi, Weiran Wang, Yunfei Wu, Shuang Qu, Jing Li, Hongwei Liang, Ke Zen   +7 more
doaj   +1 more source

Locked and Loaded: Mechanisms Regulating Natural Killer Cell Lytic Granule Biogenesis and Release

Frontiers in Immunology, 2022
NK cell-mediated cytotoxicity is a critical element of our immune system required for protection from microbial infections and cancer. NK cells bind to and eliminate infected or cancerous cells via direct secretion of cytotoxic molecules toward the bound
Hyoungjun Ham, Michael Medlyn, Daniel D. Billadeau, Daniel D. Billadeau   +3 more
doaj   +1 more source

Cold Agglutinins and Cryoglobulins Associate With Clinical and Laboratory Parameters of Cold Urticaria

Frontiers in Immunology, 2021
Mast cell-activating signals in cold urticaria are not yet well defined and are likely to be heterogeneous. Cold agglutinins and cryoglobulins have been described as factors possibly associated with cold urticaria, but their relevance has not been ...
Mojca Bizjak, Mitja Košnik, Dorothea Terhorst-Molawi, Dejan Dinevski, Marcus Maurer   +4 more
doaj   +1 more source

1-Iodohexadecane Alleviates 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis in Mice: Possible Involvements of the Skin Barrier and Mast Cell SNARE Proteins

Molecules, 2022
Atopic dermatitis (AD) is a chronic inflammatory dermal disease with symptoms that include inflammation, itching, and dry skin. 1-Iodohexadecane is known as a component of Chrysanthemum boreale essential oil that has an inhibitory effect on AD-like ...
Do Yoon Kim, Kyung-Jong Won, Dae Il Hwang, Nan Young Kim, Bokyung Kim, Hwan Myung Lee   +5 more
doaj   +1 more source

Myeloperoxidase: Regulation of Neutrophil Function and Target for Therapy

Antioxidants, 2022
Neutrophils, the most abundant white blood cells in humans, are critical for host defense against invading pathogens. Equipped with an array of antimicrobial molecules, neutrophils can eradicate bacteria and clear debris.
Salma A. Rizo-Téllez, Meriem Sekheri, János G. Filep   +2 more
doaj   +1 more source

DOCK2 Mutation and Recurrent Hemophagocytic Lymphohistiocytosis

Life, 2023
Hemophagocytic lymphohistiocytosis (HLH) is a syndrome resulting from uncontrolled hyper-inflammation, excessive immune system activation, and elevated levels of inflammatory cytokines.
Daniel D. Reiff, Mingce Zhang, Randy Q. Cron   +2 more
doaj   +1 more source