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The Enigma of Eosinophil Degranulation [PDF]
International Journal of Molecular Sciences, 2021 Eosinophils are specialized white blood cells, which are involved in the pathology of diverse allergic and nonallergic inflammatory diseases. Eosinophils are traditionally known as cytotoxic effector cells but have been suggested to additionally play a ...
Timothée Fettrelet +4 more
semanticscholar +4 more sources
Neutrophil degranulation and myocardial infarction
Cell Communication and Signaling, 2022 Myocardial infarction (MI) is one of the most common cardiac emergencies with high morbidity and is a leading cause of death worldwide. Since MI could develop into a life-threatening emergency and could also seriously affect the life quality of patients,
Nan Zhang +4 more
semanticscholar +4 more sources
Marine Drugs, 2018 UV light, especially UVB, is known as a trigger of allergic reaction, leading to mast cell degranulation and histamine release. In this study, phlorotannin Fucofuroeckol-A (F-A) derived from brown algal Ecklonia stolonifera Okamura was evaluated for its ...
Thanh Sang Vo +7 more
doaj +2 more sources
Frontiers in Pharmacology, 2021 Neutrophils are crucial elements of innate immune system, which assure host defense via a range of effector functions, such as phagocytosis, degranulation, and NET formation.
Barbara Gierlikowska +4 more
doaj +2 more sources
Degranulation of Mast Cells as a Target for Drug Development
Cells, 2023 Mast cells act as key effector cells of inflammatory responses through degranulation. Mast cell degranulation is induced by the activation of cell surface receptors, such as FcεRI, MRGPRX2/B2, and P2RX7.
Bo-Gie Yang +5 more
doaj +2 more sources
Caffeic Acid Inhibits Degranulation, Cytokine Secretions, and <i>IP3 Receptor 2</i> Gene Expression in Compound 48/80-Stimulated Mouse P815 Mast Cells. [PDF]
Int J Mol SciChang KC, Lin JY.
europepmc +2 more sources
Frontiers in Pharmacology, 2021 Neutrophilic inflammatory diseases, such as chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS), or psoriasis, exert a huge burden on the global health system due to the lack of safe and effective treatments. Volatile
Michal Korinek +18 more
doaj +1 more source
Frontiers in Immunology, 2022 Host defense against bacterial and fungal infections diminishes with age. In humans, impaired neutrophil responses are thought to contribute to this decline. However, it remains unclear whether neutrophil responses are also impaired in old mice. Here, we
Kirsti Hornigold +10 more
doaj +1 more source
bioRxiv, 2021 SARS-CoV-2 infection-induced hyper-inflammation links to the acute lung injury and COVID-19 severity. Identifying the primary mediators that initiate the uncontrolled hypercytokinemia is essential for treatments.
Mengwei Wu +15 more
semanticscholar +1 more source
Mast cell distribution around the needle tract following acupuncture in Zusanli (ST36) acupoint in rats [PDF]
Bulgarian Journal of Veterinary Medicine, 2019 The aim of this study was to investigate mast cell (MCs) distribution in the vicinity of the needle tract formed after acupuncture in Zusanli (ST36) acupoint in rats.
N. D. Dimitrov +5 more
doaj +1 more source