Results 21 to 30 of about 87,250 (304)
Frontiers in Cell and Developmental Biology, 2021 Mast cells are well known for their role in allergies and many chronic inflammatory diseases. They release upon stimulation, e.g., via the IgE receptor, numerous bioactive compounds from cytoplasmic secretory granules. The regulation of granule secretion
Gaël Ménasché +5 more
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Anti-allergic Inflammatory Effects of the Essential Oil From Fruits of Zanthoxylum coreanum Nakai
Frontiers in Pharmacology, 2018 Zanthoxylum coreanum Nakai is a rare shrub which grows in Korea and China. Pericarp of Z. coreanum has been used as a crude medicine, but there are few researches about the pharmacologic activities.
Rui Hong Guo +8 more
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Mechanisms of eosinophil cytokine release
Memorias do Instituto Oswaldo Cruz, 2005 Human eosinophils have been demonstrated to contain a multitude of cytokines and chemokines that exist pre-formed within these cells. This content of pre-formed cytokines, with diverse potential biologic activities, provides eosinophils with capabilities
Christianne Bandeira-Melo +1 more
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Anti-Allergic Activity of Monoacylated Ascorbic Acid 2-Glucosides
Molecules, 2017 2-O-α-d-Glucopyranosyl-l-ascorbic acid (AA-2G) is one of the stable ascorbic acid (AA) derivatives known as provitamin C agents. We have previously synthesized two types of monoacylated derivatives of AA-2G, 6-O-acyl-2-O-α-d-glucopyranosyl-l-ascorbic ...
Kaori Miura +5 more
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Mast Cell Activation Triggered by Retrovirus Promotes Acute Viral Infection
Frontiers in Microbiology, 2022 Mast cells (MCs) are strategically located at the host-environment interface and their non-allergic roles in the immune-surveillance of pathogens have recently gained more attention.
Shu-Ting Song +7 more
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The Anti-apoptotic Murine Cytomegalovirus Protein vMIA-m38.5 Induces Mast Cell Degranulation
Frontiers in Cellular and Infection Microbiology, 2020 Mast cells (MC) represent “inbetweeners” of the immune system in that they are part of innate immunity by acting as first-line sentinels for environmental antigens but also provide a link to adaptive immunity by secretion of chemokines that recruit CD8 T
Julia K. Schmiedeke +5 more
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Degranulating Eosinophils in Human Endometriosis [PDF]
The American Journal of Pathology, 2000 Degranulating eosinophils have been described in most endometrial cancers. We hypothesized that endometriosis (ectopic, nonneoplastic endometrial tissue) would be an appropriate model system for determining whether eosinophil degranulation is part of a specific immune response to endometrial cancer or if it is related to the more general phenomenon of ...
R D, Blumenthal +5 more
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Neutrophil degranulation and myocardial infarction
Cell Communication and Signaling, 2022 Abstract Myocardial infarction (MI) is one of the most common cardiac emergencies with high morbidity and is a leading cause of death worldwide. Since MI could develop into a life-threatening emergency and could also seriously affect the life quality of patients, continuous efforts have been made to create an effective strategy to ...
Nan Zhang +4 more
openaire +3 more sources
Microorganisms, 2016 Mast cells play a critical role in immunoglobulin E (IgE)-mediated allergic diseases, and the degranulation of mast cells is important in the pathogenesis of these diseases. A disturbance of the intestinal microflora, especially of endogenous lactic acid
Gaku Harata +7 more
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Non-canonical activation of PI3Kγ by Ca²⁺/PKCβ in mast cells [PDF]
, 2014 Mast cells are key effector cells in allergic disease triggering inflammation through mediator release. Allergens activate mast cells through the high-affinity receptor for IgE (FcεRI), which initiates signalling pathways that regulate the release of
Walser, Romy
core +1 more source