Results 21 to 30 of about 137,298 (386)

A role for eosinophils in the intestinal immunity against infective Ascaris suum larvae [PDF]

open access: yes, 2013
The aim of this study was to explore the mechanisms of resistance against invading Ascaris suum larvae in pigs. Pigs received a low dose of 100 A. suum eggs daily for 14 weeks.
Chiers, Koen   +6 more
core   +9 more sources

Degranulation response in cytotoxic rat lymphocytes measured with a novel CD107a antibody

open access: yesFrontiers in Immunology, 2016
Measuring degranulation through CD107a expression has become an advantageous tool for testing the functional capacity of cytotoxic cells. Such functional studies have been hampered in the rat by the lack of a suitable anti-rat CD107a antibody.
Amanda Sudworth   +3 more
doaj   +1 more source

Stimulation of TRPV1 by green laser light [PDF]

open access: yes, 2012
Low-level laser irradiation of visible light had been introduced as a medical treatment already more than 40 years ago, but its medical application still remains controversial.
Gu, Quanbao   +3 more
core   +2 more sources

Manipulating neutrophil degranulation as a bacterial virulence strategy

open access: yesPLoS Pathogens, 2020
Armed with an arsenal of antimicrobial mechanisms, neutrophils are among the first innate immune cells recruited to the site of bacterial infection.
K. Eichelberger, W. Goldman
semanticscholar   +1 more source

ORMDL3 Functions as a Negative Regulator of Antigen-Mediated Mast Cell Activation via an ATF6-UPR-Autophagy–Dependent Pathway

open access: yesFrontiers in Immunology, 2021
Antigen (Ag)-mediated mast cell activation plays a critical role in the immunopathology of IgE-dependent allergic diseases. Restraining the signaling cascade that regulates the release of mast cell-derived inflammatory mediators is an attractive ...
Jia Li   +10 more
doaj   +1 more source

Mast cell subsets and their functional modulation by the Acanthocheilonema viteae product ES-62 [PDF]

open access: yes, 2013
ES-62, an immunomodulator secreted by filarial nematodes, exhibits therapeutic potential in mouse models of allergic inflammation, at least in part by inducing the desensitisation of Fc휀RI-mediated mast cell responses.
Al-Riyami, Lamyaa   +7 more
core   +2 more sources

Phosphodiesterase 4 inhibitors attenuate virus‐induced activation of eosinophils from asthmatics without affecting virus binding

open access: yesPharmacology Research & Perspectives, 2020
Acute respiratory virus infections, such as influenza and RSV, are predominant causes of asthma exacerbations. Eosinophils act as a double‐edged sword in exacerbations in that they are activated by viral infections but also can capture and inactivate ...
Yanaika Shari Sabogal Piñeros   +8 more
doaj   +1 more source

Cytoskeletal Transport, Reorganization, and Fusion Regulation in Mast Cell-Stimulus Secretion Coupling

open access: yesFrontiers in Cell and Developmental Biology, 2021
Mast cells are well known for their role in allergies and many chronic inflammatory diseases. They release upon stimulation, e.g., via the IgE receptor, numerous bioactive compounds from cytoplasmic secretory granules. The regulation of granule secretion
Gaël Ménasché   +5 more
doaj   +1 more source

Epithelial cells expressed IL-33 to promote degranulation of mast cells through inhibition on ST2/PI3K/mTOR-mediated autophagy in allergic rhinitis

open access: yesCell Cycle, 2020
Nasal epithelial cells are the first barrier against allergen infiltration in allergic rhinitis (AR), and the relationship between nasal epithelial cells and mast cell-mediated hypersensitivity remains unclear.
J. Nian   +6 more
semanticscholar   +1 more source

Tissue eosinophilia and eosinophil degranulation in Riedel's invasive fibrous thyroiditis. [PDF]

open access: yes, 1996
The etiology of Riedel's invasive fibrous thyroiditis (IFT) has remained obscure. This rare disorder has been confused in the past with the more common fibrous variant of Hashimoto's disease.
Bahn, R. S.   +4 more
core   +1 more source

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