Results 31 to 40 of about 116,525 (341)
Marine Drugs, 2018 UV light, especially UVB, is known as a trigger of allergic reaction, leading to mast cell degranulation and histamine release. In this study, phlorotannin Fucofuroeckol-A (F-A) derived from brown algal Ecklonia stolonifera Okamura was evaluated for its ...
Thanh Sang Vo +7 more
doaj +1 more source
The Anti-apoptotic Murine Cytomegalovirus Protein vMIA-m38.5 Induces Mast Cell Degranulation
Frontiers in Cellular and Infection Microbiology, 2020 Mast cells (MC) represent “inbetweeners” of the immune system in that they are part of innate immunity by acting as first-line sentinels for environmental antigens but also provide a link to adaptive immunity by secretion of chemokines that recruit CD8 T
Julia K. Schmiedeke +5 more
doaj +1 more source
Allergo oncology: Targeted degranulation [PDF]
Open Access Research Journal of Science and Technology, 2023 Allergies are an inevitable part of life, no matter where we live. Without a doubt, the symptoms of allergies can cause severe physical and mental suffering. Although medical science has made great strides in suppressing allergy symptoms with medicines, immunotherapies, and virus-like particle technology (i.e., Allergy Vaccines), research indicates ...
Michael John Dochniak +1 more
openalex +2 more sources
Amniotic fluid embolism pathophysiology suggests the new diagnostic armamentarium: β-tryptase and complement fractions C3-C4 are the indispensable working tools [PDF]
, 2015 Amniotic fluid embolism (AFE) is an uncommon obstetric condition involving pregnant women during labor or in the initial stages after delivery. Its incidence is estimated to be around 5.5 cases per 100,000 deliveries.
Busardo', FRANCESCO PAOLO +3 more
core +2 more sources
SARS-CoV-2 Dysregulates Neutrophil Degranulation and Reduces Lymphocyte Counts
Biomedicines, 2022 SARS-CoV-2, the virus that causes COVID-19, has given rise to one of the largest pandemics, affecting millions worldwide. High neutrophil-to-lymphocyte ratios have been identified as an important correlate to poor recovery rates in severe COVID-19 ...
Abenaya Muralidharan +2 more
doaj +1 more source
Neutrophil degranulation and myocardial infarction
Cell Communication and Signaling, 2022 AbstractMyocardial infarction (MI) is one of the most common cardiac emergencies with high morbidity and is a leading cause of death worldwide. Since MI could develop into a life-threatening emergency and could also seriously affect the life quality of patients, continuous efforts have been made to create an effective strategy to prevent the occurrence
Nan Zhang +4 more
openaire +3 more sources
Heterotrimeric G-protein subunit Gαi2 contributes to agonist-sensitive apoptosis and degranulation in murine platelets [PDF]
, 2018 Gαi2, a heterotrimeric G-protein subunit, regulates various cell functions including ion channel activity, cell differentiation, proliferation and apoptosis.
Birnbaumer, Lutz +12 more
core +1 more source
Cells, 2021 The identification of the Mas-related G-protein-coupled receptors (Mrgpr) as targets of diverse stimuli of mast cells (MCs), including neuropeptides and pseudo-allergy causing drugs, has placed these receptors at a prime position in MC research. However,
Pia Lazki-Hagenbach +2 more
doaj +1 more source
Microorganisms, 2016 Mast cells play a critical role in immunoglobulin E (IgE)-mediated allergic diseases, and the degranulation of mast cells is important in the pathogenesis of these diseases. A disturbance of the intestinal microflora, especially of endogenous lactic acid
Gaku Harata +7 more
doaj +1 more source
Avidity of influenza-specific memory CD8+ T-cell populations decays over time compromising antiviral immunity [PDF]
, 2012 Decline of cell-mediated immunity is often attributed to decaying T-cell numbers and their distribution in peripheral organs. This study examined the hypothesis that qualitative as well as quantitative changes contribute to the declining efficacy of CD8+
Alexander-Miller +41 more
core +1 more source