Results 101 to 110 of about 1,641 (192)

Delafloxacin: A New Anti–methicillin-resistant Staphylococcus aureus Fluoroquinolone

open access: yesClinical Infectious Diseases, 2018
Delafloxacin (ABT 492) is a new fluoroquinolone available in both oral and parenteral formulations. It has recently been approved by the Food and Drug Administration for the management of acute bacterial skin and skin structure infections. When compared to combination therapy of vancomycin and aztreonam, delafloxacin was not inferior and had a ...
Louis D, Saravolatz, Gary E, Stein
openaire   +2 more sources

In vitro characterization of delafloxacin activity against intracellular Legionella: Exploring new treatment options for Legionnaires’ disease

open access: yesInternational Journal of Infectious Diseases
Objectives: Delafloxacin is a fourth-generation fluoroquinolone that is currently approved in Europe and the United States for bacterial infections of the skin and skin structures and for community-acquired pneumonia, including cases where it is caused ...
Roger Cortès-Tarragó   +10 more
doaj   +1 more source

Risk of Multidrug-Resistant Pathogens in Severe Community-Acquired Pneumonia [PDF]

open access: yes
Severe community-acquired pneumonia (SCAP) is difficult to treat when caused by difficult-to-treat (DTR) pathogens because of limited treatment options and poorer clinical outcomes.
Areny-Balagueró, Aina   +5 more
core   +1 more source

A novel liquid chromatography-fluorescence method for the determination of delafloxacin in human plasma [PDF]

open access: yes, 2022
Escudero Pastor, Elisa   +2 more
core   +1 more source

Study on microbiological and sorption removal character of fluoroquinolones for hospital wastewater treatment [PDF]

open access: yes, 2021
Nagasaki University (長崎大学)博士(工学)長崎大学学位論文 学位記番号:博(工)甲第99号 学位授与年月日:令和3年3月22日Nagasaki University (長崎大学), 博士(工学) (2021-03-22)doctoral ...
Dang, Bao Trong
core  

Quinolone Allergy [PDF]

open access: yes, 2019
Quinolones are the second most common antibiotic class associated with drug-induced allergic reactions, but data on quinolone allergy are scarce. This review article discusses the available evidence on quinolone allergy, including prevalence, risk ...
Boronea, Bernadett   +5 more
core   +1 more source

Antimicrobial Agents: Antibacterial Agents, Anti-biofilm Agents, Antibacterial Natural Compounds, and Antibacterial Chemicals [PDF]

open access: yes, 2019
The surge in antimicrobial resistance coupled with the decline in the antimicrobial drug pipeline calls for the discovery and development of new agents to tackle antibiotic resistance and prevent a return to a post-antibiotic era. Several factors account
Adu, Francis   +4 more
core   +1 more source

Efficacy and safety of delafloxacin in the treatment of acute bacterial skin and skin structure infections: a systematic review and meta-analysis of randomized controlled trials

open access: yesInfection and Drug Resistance, 2019
Shao-Huan Lan,1 Chih-Cheng Lai,2 Li-Chin Lu,3 Shen-Peng Chang,4 Hui-Ting Huang41School of Pharmaceutical Sciences and Medical Technology, Putian University, Putian, People’s Republic of China; 2Department of Intensive Care Medicine, Chi Mei Medical
Lan SH   +4 more
doaj  

Polymicrobial Interactions Induce Multidrug Tolerance in Staphylococcus aureus Through Energy Depletion

open access: yesFrontiers in Microbiology, 2019
Staphylococcus aureus is responsible for a high number of relapsing infections, which are often mediated by the protective nature of biofilms. Polymicrobial biofilms appear to be more tolerant to antibiotic treatment, however, the underlying mechanisms ...
Dan L. Nabb   +5 more
doaj   +1 more source

Ciprofloxacin and levofloxacin attenuate microglia inflammatory response via TLR4/NF-kB pathway [PDF]

open access: yes, 2019
BACKGROUND: Neuroinflammation is the response of the central nervous system to events that interfere with tissue homeostasis and represents a common denominator in virtually all neurological diseases.
Franceschini D.   +8 more
core   +1 more source

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