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Delafloxacin: A New Anti–methicillin-resistant Staphylococcus aureus Fluoroquinolone
Delafloxacin (ABT 492) is a new fluoroquinolone available in both oral and parenteral formulations. It has recently been approved by the Food and Drug Administration for the management of acute bacterial skin and skin structure infections. When compared to combination therapy of vancomycin and aztreonam, delafloxacin was not inferior and had a ...
Louis D, Saravolatz, Gary E, Stein
openaire +2 more sources
Objectives: Delafloxacin is a fourth-generation fluoroquinolone that is currently approved in Europe and the United States for bacterial infections of the skin and skin structures and for community-acquired pneumonia, including cases where it is caused ...
Roger Cortès-Tarragó +10 more
doaj +1 more source
Risk of Multidrug-Resistant Pathogens in Severe Community-Acquired Pneumonia [PDF]
Severe community-acquired pneumonia (SCAP) is difficult to treat when caused by difficult-to-treat (DTR) pathogens because of limited treatment options and poorer clinical outcomes.
Areny-Balagueró, Aina +5 more
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A novel liquid chromatography-fluorescence method for the determination of delafloxacin in human plasma [PDF]
Escudero Pastor, Elisa +2 more
core +1 more source
Study on microbiological and sorption removal character of fluoroquinolones for hospital wastewater treatment [PDF]
Nagasaki University (長崎大学)博士(工学)長崎大学学位論文 学位記番号:博(工)甲第99号 学位授与年月日:令和3年3月22日Nagasaki University (長崎大学), 博士(工学) (2021-03-22)doctoral ...
Dang, Bao Trong
core
Quinolones are the second most common antibiotic class associated with drug-induced allergic reactions, but data on quinolone allergy are scarce. This review article discusses the available evidence on quinolone allergy, including prevalence, risk ...
Boronea, Bernadett +5 more
core +1 more source
Antimicrobial Agents: Antibacterial Agents, Anti-biofilm Agents, Antibacterial Natural Compounds, and Antibacterial Chemicals [PDF]
The surge in antimicrobial resistance coupled with the decline in the antimicrobial drug pipeline calls for the discovery and development of new agents to tackle antibiotic resistance and prevent a return to a post-antibiotic era. Several factors account
Adu, Francis +4 more
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Shao-Huan Lan,1 Chih-Cheng Lai,2 Li-Chin Lu,3 Shen-Peng Chang,4 Hui-Ting Huang41School of Pharmaceutical Sciences and Medical Technology, Putian University, Putian, People’s Republic of China; 2Department of Intensive Care Medicine, Chi Mei Medical
Lan SH +4 more
doaj
Staphylococcus aureus is responsible for a high number of relapsing infections, which are often mediated by the protective nature of biofilms. Polymicrobial biofilms appear to be more tolerant to antibiotic treatment, however, the underlying mechanisms ...
Dan L. Nabb +5 more
doaj +1 more source
Ciprofloxacin and levofloxacin attenuate microglia inflammatory response via TLR4/NF-kB pathway [PDF]
BACKGROUND: Neuroinflammation is the response of the central nervous system to events that interfere with tissue homeostasis and represents a common denominator in virtually all neurological diseases.
Franceschini D. +8 more
core +1 more source

