Results 91 to 100 of about 1,641 (192)

Lip necrosis caused by methicillin‐resistant Staphylococcus aureus (MRSA)

JEADV Clinical Practice, Volume 3, Issue 4, Page 1253-1257, September 2024.
Abstract Labial necrosis is a rare condition with diverse causes, posing challenges for diagnosis and treatment. Methicillin‐resistant Staphylococcus aureus (MRSA) strains, particularly those positive for Panton‐Valentine leukocidin (PVL), further complicate management due to antibiotic resistance and heightened virulence.
Saad Khayat, Marc Agea Martínez, Manuel Tousidonis Rial, Alberto Diez Montiel, Santiago Ochandiano Caicoya   +4 more
wiley   +1 more source

What is the role of microbial biotechnology and genetic engineering in medicine?

MicrobiologyOpen, Volume 13, Issue 2, April 2024.
Microbial biotechnology, the technological application of microorganisms, has been instrumental in producing significant natural bioactive products. These include antibiotics, antifungals, anticancer drugs, antiparasitics, antivirals, immunosuppressants, toxoid vaccines, and therapeutic enzymes.
Fernando Santos‐Beneit
wiley   +1 more source

Safety of Delafloxacin: Focus on Adverse Events of Special Interest

Open Forum Infectious Diseases, 2018
AbstractBackgroundFluoroquinolones have been widely used for a variety of Gram-positive and Gram-negative infections, and by 2002 they had become the most commonly prescribed class of antibiotics for adults in the United States. With widespread use, the class has become associated with a range of adverse events.
Thomas Lodise, Ralph Corey, David Hooper, Sue Cammarata   +3 more
openaire   +2 more sources

Acute bacterial skin and soft tissue infections: new drugs in ID armamentarium

Journal of Community Hospital Internal Medicine Perspectives, 2019
Acute bacterial skin and soft tissue infections (SSTI) are among the most common reasons for hospitalization of adults in the USA today. Cellulitis or SSTI can cause significant morbidity and mortality.
Raghavendra Tirupathi, Swetha Areti, Sohail A. Salim, Venkatraman Palabindala, Nageshwar Jonnalagadda   +4 more
doaj   +1 more source

A case study on Staphylococcus aureus bacteraemia: available treatment options, antibiotic R&D and responsible antibiotic-use strategies [PDF]

, 2020
Objectives This case study addresses: (i) antibiotic treatment options for Staphylococcus aureus bacteraemia (SAB), for both empirical and targeted therapy; (ii) the current status of and priorities for the antibiotic pipeline to ensure
Cavaleri, Marco, Gyssens, Inge C, Monnier, Annelie A, Tacconelli, Evelina, Årdal, Christine   +4 more
core   +1 more source

Interventions in the management of diabetes‐related foot infections: A systematic review

Diabetes/Metabolism Research and Reviews, Volume 40, Issue 3, March 2024.
Abstract The optimal approaches to managing diabetic foot infections remain a challenge for clinicians. Despite an exponential rise in publications investigating different treatment strategies, the various agents studied generally produce comparable results, and high‐quality data are scarce. In this systematic review, we searched the medical literature
Edgar J. G. Peters, Zaina Albalawi, Suzanne A. van Asten, Zulfiqarali G. Abbas, Geneve Allison, Javier Aragón‐Sánchez, John M. Embil, Lawrence A. Lavery, Majdi Alhasan, Orhan Oz, Ilker Uçkay, Vilma Urbančič‐Rovan, Zhang‐Rong Xu, Éric Senneville   +13 more
wiley   +1 more source

Emergence of Delafloxacin-Resistant Staphylococcus aureus in Brooklyn, New York

Clinical Infectious Diseases, 2019
Abstract Delafloxacin is an option for infections due to methicillin-resistant Staphylococcus aureus. In 2017, 22% of isolates from 7 hospitals in Brooklyn, New York, were nonsusceptible to delafloxacin. Isolates belonging to ST105, a strain associated with healthcare-related infections, predominated.
Alejandro, Iregui, Zeb, Khan, Saquib, Malik, David, Landman, John, Quale   +4 more
openaire   +2 more sources

GENETIC SEQUENCING AND EVALUATION OF DELAFLOXACIN SUSCEPTIBILITY IN COMMUNITY-ACQUIRED MRSA CAUSING SKIN, SOFT TISSUE, AND MUSCULOSKELETAL INFECTIONS

Brazilian Journal of Infectious Diseases
Introduction/Objective: Indiscriminate use of quinolones, especially after the COVID-19 pandemic, has contributed to increased bacterial resistance, including methicillin-resistant Staphylococcus aureus (MRSA).
Stefânia Bazanelli Prebianchi, Ingrid Nayara Marcelino Santos, Isabelle Brasil, Mariana Neri Lucas Kurihara, Rafael Brull Tuma, Mauro José Costa Salles   +5 more
doaj   +1 more source

Novel Antibiotics for Multidrug-Resistant Gram-Positive Microorganisms

Microorganisms, 2019
Increasing multidrug-resistance to Gram-positive pathogens, particularly to staphylococci, enterococci and streptococci, is a major problem, resulting in significant morbidity, mortality and healthcare costs. In recent years, only a small number of novel
Despoina Koulenti, Elena Xu, Isaac Yin Sum Mok, Andrew Song, Drosos E. Karageorgopoulos, Apostolos Armaganidis, Jeffrey Lipman, Sotirios Tsiodras   +7 more
doaj   +1 more source

Restriction of arginine induces antibiotic tolerance in Staphylococcus aureus [PDF]

Staphylococcus aureus is responsible for a substantial number of invasive infections globally each year. These infections are problematic because they are frequently recalcitrant to antibiotic treatment.
Cassat, James E., Curry, Jacob M., Freiberg, Jeffrey A., Gimza, Brittney D., Green, Erin R., Murdoch, Caitlin C., Reyes Ruiz, Valeria M., Skaar, Eric P.   +7 more
core   +1 more source