The Pharmaceutical Industry in 2017. An Analysis of FDA Drug Approvals from the Perspective of Molecules [PDF]
This is an analysis from a chemical point of view of the 46 drugs (34 New Chemical Entities and 12 Biologics) approved by the FDA during 2017. The drugs included in the 2017 "harvest" have been classified on the basis of their chemical structure ...
Albericio Palomera, Fernando +1 more
core +1 more source
Benzo[b]thiophene‐1,3,4‐oxadizole and 1,2,4‐oxadiazole hybrids 9a–9l were tested against both antibacterial and anticancer, revealing interesting structure‐activity relationships. density functional theory calculations (DFTs) at the B3LYP/6–311++G (d,p).
Ravikumar Gupta Miriyala +5 more
wiley +1 more source
P41 Use of delafloxacin in osteomyelitis: a case report
Abstract Background Data and experience with delafloxacin use in osteomyelitis (OM) and other deep-seated infections are limited, yet the burden of OM on healthcare systems is significant. We hereby describe the first case, to our knowledge, of delafloxacin use in OM.
Vidwans, Madhuri +2 more
openaire +1 more source
Corn cob pyrolysis: A systematic literature review of methods and applications
Mapping the research landscape of corn cob pyrolysis. Abstractas The agricultural sector is experiencing a surge in waste generation due to population growth, creating an urgent need to convert byproducts into value‐added products. Maize (Zea mays L.), a leading global crop, produces significant byproducts, such as corn cob, which are often undervalued.
Vilmar Steffen +5 more
wiley +1 more source
Genotypic and phenotypic characterization of antimicrobial resistance in Neisseria gonorrhoeae: A cross-sectional study of isolates recovered from routine urine cultures in a high-incidence setting [PDF]
The objectives of this study were to perform genomic and phenotypic characterization of antimicrobial resistance in Neisseria gonorrhoeae isolates recovered from urine samples from patients in St. Louis, MO, USA.
Bailey, Adam L +5 more
core +2 more sources
Etiology and efficacy of anti-microbial treatment for community-acquired pneumonia in adults requiring hospital admission in Ukraine [PDF]
Background and aim: Empiric therapy of community-acquired pneumonia (CAP) remains the standard care and guidelines are mostly based on published data from the United States or Europe.
Baranovskaya, Tatiana +17 more
core +1 more source
Antibiotic Resistance: A Genetic and Physiological Perspective
The development of resistance to antimicrobials and their historical progression are depicted in this graphic. It draws attention to important biochemical, physiological, and genetic factors that contribute to AMR, such as the transmission of genes, the development of biofilms, and the inactivation of antibiotics.
Rania G. Elbaiomy +9 more
wiley +1 more source
Drug Safety Monitoring Information
Analysis of administrative decisions of foreign regulatory authorities on the recall of medicines and/or the need for changes in the instructions for their medical use due to changes in the safety profile, conducted by experts of the Scientific Centre for ...
E. V. Shubnikova +4 more
doaj +1 more source
A review of antibiotic safety in pregnancy—2025 update
Abstract Antibiotics constitute the majority of prescriptions for women during pregnancy. Common bacterial infections, including urinary tract infections, skin and soft tissue infections, and upper and lower respiratory tract infections, are expected in pregnancy, similar to the general public.
Johny Nguyen +8 more
wiley +1 more source
Treatment of methicillin-resistant Staphylococcus aureus (MRSA): updated guidelines from the UK [PDF]
These evidence-based guidelines are an updated version of those issued in 2008. They have beenproduced following a review of the published literature (2007-18) pertaining to the treatment of infections caused by MRSA.
Brown, Erwin M +4 more
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