Results 61 to 70 of about 1,641 (192)
Emerging antibiotics for community-acquired pneumonia [PDF]
, 2019 Introduction: Community-acquired pneumonia is the most common infection leading to hospitalization and death in all age groups, especially in elderly populations.
Cillóniz, Catia +3 more
core +1 more source
REVIEW ON CLINICALLY DEVELOPING ANTIBIOTICS [PDF]
, 2018 The world is running out of antibiotics. Between 1940 and 1962, more than 20 new classes of antibiotics were marketed. Since then, only two new classes of antibiotics were marketed.
M., Sudha +3 more
core +3 more sources
FDA-Approved Fluorinated Heterocyclic Drugs from 2016 to 2022 [PDF]
, 2023 The inclusion of fluorine atoms or heterocyclic moiety into drug structures represents a recurrent motif in medicinal chemistry. The combination of these two features is constantly appearing in new molecular entities with various biological activities ...
Amata S. +5 more
core +1 more source
Linezolid and Rifampicin Combination to Combat cfr-Positive Multidrug-Resistant MRSA in Murine Models of Bacteremia and Skin and Skin Structure Infection. [PDF]
, 2019 Linezolid resistance mediated by the cfr gene in MRSA represents a global concern. We investigated relevant phenotype differences between cfr-positive and -negative MRSA that contribute to pathogenesis, and the efficacy of linezolid-based combination ...
Li, Liang +6 more
core
Synthesis of an Enzyme‐Triggered Chitosan‐Based Drug Delivery System for Peri‐Implantitis Prevention
Chemistry – A European Journal, Volume 32, Issue 16, 25 April 2026.ABSTRACT Dental implants have become a leading solution for tooth loss, yet bacterial infections remain a major complication. Antibacterial implant coatings are an important approach to reduce or prevent bacterial infections at the implant. Given the oral cavity's complex microbiome and the importance of some commensal bacteria, it is crucial to ...
Nelly Senze Nnane +7 more
wiley +1 more source
Antibiotics, 2020 In this work; delafloxacin (DLFX) was determined using a validated green RP-HPTLC and NP-HPTLC methods in commercial tablets and in-house developed solid lipid nanoparticles (SLNs).
Prawez Alam +7 more
doaj +1 more source
Estimating Renal Function in Drug Development: Time to Take the Fork in the Road [PDF]
, 2019 Renal function is the most commonly applied patient‐specific quantitative variable used to determine drug doses. Measurement of renal function is not practical in most clinical settings; therefore, clinicians often rely on estimates when making dosing ...
Accetta +34 more
core +1 more source
New antibiotics for the treatment of acute bacterial skin and soft tissue infections in pediatrics [PDF]
, 2020 Acute bacterial skin and soft tissue infections (aSSTIs) are a large group of diseases that can involve exclusively the skin or also the underlying subcutaneous tissues, fascia, or muscles.
Argentiero A. +4 more
core +2 more sources
Frontiers in the Management of Orthopaedic Periprosthetic Joint Infection
Journal of Orthopaedic Research, Volume 44, Issue 2, February 2026.ABSTRACT Periprosthetic joint infection (PJI) is a devastating complication of total joint arthroplasty (TJA), one of the most frequently performed surgical procedures worldwide. Management of acute PJI commonly involves debridement, antibiotics, and implant retention (DAIR), though failure rates remain high due to antibiotic‐tolerant biofilms. Chronic
Michael F. Shannon +9 more
wiley +1 more source
Case Reports in Pulmonology, 2022 Purpose. We report the development of a lung abscess caused by a ciprofloxacin-resistant Pseudomonas aeruginosa in a patient with COVID-19 on long-term corticosteroid therapy.
Jürgen Panholzer +8 more
doaj +1 more source