Results 51 to 60 of about 1,641 (192)

Sexually transmitted infections: challenges ahead. [PDF]

open access: yes, 2017
WHO estimated that nearly 1 million people become infected every day with any of four curable sexually transmitted infections (STIs): chlamydia, gonorrhoea, syphilis, and trichomoniasis.
Bradshaw, Catriona S   +13 more
core   +5 more sources

A Phase 3 Study to Compare Delafloxacin With Moxifloxacin for the Treatment of Adults With Community-Acquired Bacterial Pneumonia (DEFINE-CABP) [PDF]

open access: yes, 2019
The clinical and economic burden of community-acquired bacterial pneumonia (CABP) is significant and is anticipated to increase as the population ages and pathogens become more resistant.
Cammarata, Sue   +8 more
core   +1 more source

Estimation of Delafloxacin Using Derivative Spectrophotometry and Area Under Curve in Bulk Material and in Laboratory Mixture [PDF]

open access: yes, 2016
Simple, specific, rapid and accurate UV-spectrophotometric methods have been developed using a solvent acetonitrile (50 %) to determine delafloxacin in bulk material and in laboratory mixture.
Atul A. Shirkhedkar, Kiran R. Dhangar
core   +2 more sources

Superbugs or multidrug resistant microbes: A new threat to the society

open access: yes, 2023
Health Science Reports, Volume 6, Issue 8, August 2023.
Sakshi Painuli   +3 more
wiley   +1 more source

Delafloxacin Pharmacokinetics in Subjects With Varying Degrees of Renal Function [PDF]

open access: yesThe Journal of Clinical Pharmacology, 2017
AbstractDelafloxacin, a fluoroquinolone, has activity against gram‐positive organisms including methicillin‐resistant Staphylococcus aureus and fluoroquinolone‐susceptible and –resistant gram‐negative organisms. This study was conducted to determine delafloxacin pharmacokinetics after a single intravenous infusion or oral dose administration in ...
Randall K. Hoover   +5 more
openaire   +2 more sources

Development of Lipomer Nanoparticles for the Enhancement of Drug Release, Anti-Microbial Activity and Bioavailability of Delafloxacin

open access: yesPharmaceutics, 2020
Delafloxacin (DFL) is a novel potent and broad-spectrum fluoroquinolone group of antibiotics effective against both Gram-positive and negative aerobic and anaerobic bacteria.
Md. Khalid Anwer   +7 more
doaj   +1 more source

Eco-Friendly UPLC-MS/MS Quantitation of Delafloxacin in Plasma and Its Application in a Pharmacokinetic Study in Rats

open access: yesSeparations, 2021
A novel UPLC-MS/MS assay was developed for rapid quantification of delafloxacin (a novel fluoroquinolone antibiotic in plasma samples by one step sample cleanup procedure.
Muzaffar Iqbal   +3 more
doaj   +1 more source

New Antimicrobials for Gram-Positive Sustained Infections: A Comprehensive Guide for Clinicians

open access: yesPharmaceuticals, 2023
Antibiotic resistance is a public health problem with increasingly alarming data being reported. Gram-positive bacteria are among the protagonists of severe nosocomial and community infections.
Davide Carcione   +13 more
doaj   +1 more source

The Epidemiology of Antibiotic-Related Adverse Events in the Treatment of Diabetic Foot Infections: A Narrative Review of the Literature [PDF]

open access: yes, 2023
The use of antibiotics for the treatment of diabetic foot infections (DFIs) over an extended period of time has been shown to be associated with adverse events (AEs), whereas interactions with concomitant patient medications must also be considered.
Huber, Tanja   +6 more
core   +1 more source

Overview of Side-Effects of Antibacterial Fluoroquinolones: New Drugs versus Old Drugs, a Step Forward in the Safety Profile?

open access: yesPharmaceutics, 2023
Antibacterial fluoroquinolones (FQs) are frequently used in treating infections. However, the value of FQs is debatable due to their association with severe adverse effects (AEs).
Aura Rusu   +3 more
doaj   +1 more source

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