Results 81 to 90 of about 1,641 (192)
German evidence‐ and consensus‐based guideline on the management of penile urethritis
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 2, Page 254-275, February 2025.Summary Urethritis is a common condition predominantly caused by sexually transmitted pathogens such as Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium. It is not possible to differentiate with certainty between pathogens on the basis of clinical characteristics alone.
Ricardo Niklas Werner +30 more
wiley +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 2, Page 254-276, February 2025.Zusammenfassung Die Urethritis ist ein häufiges, überwiegend durch sexuell übertragene Erreger wie Chlamydia trachomatis, Neisseria gonorrhoeae oder Mycoplasma genitalium verursachtes Krankheitsbild. Alleine aufgrund klinischer Merkmale ist die Unterscheidung der Erreger und der Ausschluss von Koinfektionen nicht sicher möglich.
Ricardo Niklas Werner +30 more
wiley +1 more source
A Study on Repurposing of Antibiotic Drugs for Human MMPs Enzyme: A Possible Hope for Arthritis Drug [PDF]
Arthritis is a prevalent condition that primarily affects elderly individuals, especially women. Matrix Metallo proteinases (MMPs), specifically types 1,2,3,9 and 13 are key players in the progression of arthritis and represent promising drug targets for
Chakraborty, Deotima +1 more
core +2 more sources
Journal of Chemistry, Volume 2025, Issue 1, 2025.Increased antibiotic consumption and inadequate management procedures expose the environment to antibiotics, leading to significant antibiotic pollution and emerging antibiotic‐resistant microbes. Biochar form agricultural waste can efficiently remove antibiotics from aquatic environments and is a renewable and cost‐effective adsorbent.
Varalakshmi Varatharajan +3 more
wiley +1 more source
Journal of Evidence-Based Medicine, Volume 17, Issue 4, Page 729-739, December 2024.Abstract Objective To summarize the evidence on the efficacy and safety of vancomycin compared with those of alternative treatments in adult patients with methicillin‐resistant Staphylococcus aureus (MRSA) infection. Methods PubMed, Embase, and Web of Science were searched up to December 15, 2023, for systematic reviews and meta‐analyses comparing ...
Sujata Purja +4 more
wiley +1 more source
Delafloxacin: A Review in Acute Bacterial Skin and Skin Structure Infections [PDF]
Drugs, 2020 The global spread of antibacterial-resistant strains, especially methicillin-resistant Staphylococcus aureus (MRSA) for acute bacterial skin and skin structure infections (ABSSSIs), has driven the need for novel antibacterials. Delafloxacin [Quofenix™ (EU); Baxdela® (USA)], a new fluoroquinolone (FQ), has a unique chemical structure that enhances its ...
openaire +2 more sources
Mutant prevention concentration of ozenoxacin for quinolone-susceptible or -resistant Staphylococcus aureus and Staphylococcus epidermidis [PDF]
, 2020 Ozenoxacin (OZN) belongs to a new generation of non-fluorinated quinolones for the topical treatment of skin infections which has shown to be effective in the treatment of susceptible and resistant Gram-positive cocci. The mutant prevention concentration
Cantón, R. +5 more
core +1 more source
Searching for “Greener” Bioequivalents of CF3 to Lower its Environmental Impact
Chemistry – A European Journal, Volume 30, Issue 50, September 5, 2024.Considering concerns on the negative environmental effects of CF3 containing compounds, we searched for “greener” alternatives. We found −I as the best alternative since it is equivalent in all aspects studied, size, electronic and lipophilic, followed by −F, ‐cyclo‐Pr, −2‐oxetyl, −SF5 and −SCH3. We suggest using these functionalities as an alternative
Marco Minneci +2 more
wiley +1 more source
Activity of delafloxacin against methicillin-resistant Staphylococcus aureus: resistance selection and characterization [PDF]
Journal of Antimicrobial Chemotherapy, 2012 To determine the potential for delafloxacin to select for resistant mutants in methicillin-resistant Staphylococcus aureus (MRSA), including isolates with existing mutations in the quinolone resistance determining region (QRDR).Susceptibility testing by broth microdilution was performed on 30 MRSA clinical isolates.
Joan M, Remy +4 more
openaire +2 more sources
Chemical structure and pharmacokinetics of novel quinolone agents represented by avarofloxacin, delafloxacin, finafloxacin, zabofloxacin and nemonoxacin [PDF]
, 2016 Quinolones are potent antimicrobial agents with a basic chemical structure of bicyclic ring. Fluorine atom at position C-6 and various substitutions on the basic quinolone structure yielded fluoroquinolones, namely norfloxacin, ciprofloxacin ...
Bela Kocsis, D. Szabo, J. Domokos
core +1 more source