Histone Lys demethylase KDM3C demonstrates anti‐inflammatory effects by suppressing NF‐κB signaling and osteoclastogenesis [PDF]
, 2019 Jae Young Lee +8 more
openalex +1 more source
JmjC Domain-containing Histone Demethylase Gene Family in Chinese Cabbage: Genome-wide Identification and Expressional Profiling [PDF]
, 2023 Fengrui Yin +8 more
openalex +1 more source
CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling
Med Research, EarlyView.CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li +8 more
wiley +1 more source
Med Research, EarlyView.ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang +22 more
wiley +1 more source
Uncovering the Genetic Landscape of Spinal Dysraphism: A Retrospective Analysis of 150 Fetal Cases
Prenatal Diagnosis, EarlyView.ABSTRACT Objective Spinal dysraphism (SD) results from incomplete neural tube closure and encompasses a heterogeneous group of congenital anomalies with genetic and environmental etiologies. Although genetic contributions are recognized, causative variants remain insufficiently defined, and the clinical implications of extended genetic testing on ...
I. Bedei +9 more
wiley +1 more source
Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α [PDF]
, 2008 Patrick J. Pollard +6 more
openalex +1 more source
Azole antifungal contaminants disrupt mycorrhizal function and risk agricultural sustainability
PLANTS, PEOPLE, PLANET, EarlyView.Global food production is increasingly threatened by soil degradation, climate change and the rising costs of synthetic fertilisers. Circular agriculture, which promotes resource reuse, is a promising solution, but using treated wastewater and biosolids in farming introduces risks from emerging contaminants like pharmaceutical residues.
Emily K. Durant +5 more
wiley +1 more source
Pest Management Science, EarlyView.Tebuconazole‐resistant isolates overexpress CYP51 and, when tested at field rates, did not reduce ABS severity, whereas difenoconazole and mefentrifluconazole remained effective. Abstract BACKGROUND Alternaria brown spot (ABS), caused by Alternaria spp., is an important disease affecting mandarin production in several citrus‐growing regions worldwide ...
Thiago de Aguiar Carraro +7 more
wiley +1 more source
The RNA demethylases ALKBH5 and FTO regulate translation of the ATF4 mRNA in sorafenib-treated hepatocarcinoma cells [PDF]
Pauline Adjibade, Rachid Mazrouï
openalex +1 more source