Results 221 to 230 of about 95,899 (339)

In vitro evaluation of azole fungicide sensitivity in Fusarium langsethiae, F. tricinctum, F. poae and F. sporotrichioides populations from Irish oats

Pest Management Science, Volume 82, Issue 4, Page 3930-3941, April 2026.
Microtitre plate assays of 286 Irish oat isolates show species‐specific azole sensitivity. In Fusarium langsethiae, mefentrifluconazole and tebuconazole sensitivities correlate, defining four phenotypes and supporting resistance monitoring and integrated control.
Diana E. Bucur, Steven Kildea
wiley   +1 more source

Histone demethylase KDM4B epigenetically controls NLRP3 expression to enhance inflammatory responses. [PDF]

EMBO Mol Med
Tong L, Song H, Gao Y, Qin D, Wang C, Li Q, Fu Y, Zhao C, Ying Z, Chen D, Gao C, Han C, Zhao W, Qin Y, Zhang L.   +14 more
europepmc   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma. [PDF]

Cancer Res
Figuerola-Bou E, Ríos-Astorch C, Blanco E, Sánchez-Jiménez M, Táboas P, Fernández G, Gómez-González S, Muñoz O, Castellano-Escuder P, Perez-Jaume S, Garcia M, Prada E, Mateo-Lozano S, Riggi N, Avgustinova A, Lavarino C, Di Croce L, Sánchez-Molina S, Mora J.   +18 more
europepmc   +1 more source

Integration of epigenetics into ecotoxicology: insights and fundamental research needs

Biological Reviews, Volume 101, Issue 2, Page 826-847, April 2026.
ABSTRACT Epigenetics refers to heritable changes in genome function that occur without direct alterations to the DNA sequence. A multitude of environmental contaminants can influence the epigenetic marks of a genome. Changes of epigenetic marks including DNA methylation, histone modifications, and non‐coding RNAs can induce alterations at the gene ...
Albano Pinto, Jana Asselman, Patrícia Pereira, Joana Luísa Pereira   +3 more
wiley   +1 more source

Anti-tumor effects and mechanism of the histone demethylase inhibitor GSK-J4 in non-small cell lung cancer cells. [PDF]

Med Oncol
Xu D, Wang M, Wu M, Yu Y, Chen X, Wen Z, Shen D, Liu T, Chen H.   +8 more
europepmc   +1 more source

Multifaceted roles of BBX transcription factors: impacts on key agronomical traits and environmental resilience

New Phytologist, Volume 250, Issue 2, Page 762-787, April 2026.
Summary B‐box (BBX) proteins were initially characterized as transcription factors connecting light signaling to the regulation of flowering time and seedling photomorphogenesis. However, over the last decade, increasing evidence has shown that they integrate light and hormone signaling, modulating multiple physiological processes during plant life. In
Bruno Silvestre Lira, Juliene Moreira, Luciano Freschi, Magdalena Rossi   +3 more
wiley   +1 more source

Econazole Exhibits In Vitro and In Vivo Efficacy Against Leishmania amazonensis. [PDF]

Pharmaceuticals (Basel)
Mesquita JT, Dias IO, Tempone AG, Reimão JQ.   +3 more
europepmc   +1 more source

Linking Superoxide Production and Scavenging in Plant Development

Plant, Cell &Environment, Volume 49, Issue 4, Page 2048-2068, April 2026.
ABSTRACT Due to their strong oxidizing potential, rapid membrane permeability, and high reactivity, reactive oxygen species (ROS) play essential roles in plant development and stress responses. Superoxide (O2•‐) is a primary product of molecular oxygen reduction and a crucial source of hydrogen peroxide, representing a ROS species of substantial ...
Jan Řehák, Maryna Tsinyk, Petr Dvořák, Tomáš Takáč   +3 more
wiley   +1 more source

FTO-Eci1 Axis Mediates Exercise-Induced Cardioprotection in Pressure Overload Mice. [PDF]

Biomolecules
Wang J, Chang Z, Lin S, Sha G, Zeng W, Huang Q, Deng Q, Wang S, Hu M, Xia J.   +9 more
europepmc   +1 more source