Results 231 to 240 of about 98,772 (389)

Supplementary Data: list of figures and tables from (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers

Kathryn Gunn, Matti Myllykoski, John Z. Cao, Manna Ahmed, Bofu Huang, Betty Rouaisnel, Bill H. Diplas, Michael M. Levitt, Ryan Looper, John G. Doench, Keith L. Ligon, Harley I. Kornblum, Samuel K. McBrayer, Hai Yan, Cihangir Duy, Lucy A. Godley, Peppi Koivunen, Julie-Aurore Losman   +17 more
openalex   +1 more source

Renal cell carcinoma with atypical omental metastasis: A case report and literature review

UroPrecision, EarlyView.
Abstract Background Renal cell carcinoma (RCC) is the most common type of kidney cancer in adults, with common metastatic sites including the lungs, bones, liver, and brain. Omental metastasis is exceedingly rare and usually occurs postoperatively. Fumarate hydratase‐deficient (FH‐deficient) RCC, a recently classified and highly aggressive subtype of ...
Andrew Jing, Zachary Guo, Katherine Wu, Wei Wang, James Jing   +4 more
wiley   +1 more source

Decoding the immunoregulatory functions of ALKBH5 in the tumor microenvironment. [PDF]

Front Immunol
Li C, Jiang X, Yuan Y, Wang Q.
europepmc   +1 more source

Application of 23Na MRI at 7 Tesla in distinguishing IDH genotype, P53 phenotype, and Ki‐67 LI in adult‐type diffuse gliomas

VIEW, EarlyView.
Notes: Their molecular characteristics—such as IDH genotype, P53 phenotype, and Ki‐67 labeling index—are critical determinants of treatment strategies and prognosis for patients of adult‐type diffuse gliomas. In this study, we employed 7‐tesla sodium magnetic resonance imaging (23Na MRI) and demonstrated that total sodium concentration (TSC) and ...
Letian Yuan, Chaofei He, Xiaoxiao Ma, Guoli Liu, Xiangbing Bian, Song Wang, Sisi Li, Jianxun Qu, Caohui Duan, Xin Lou   +9 more
wiley   +1 more source

Data from Infection Exposure Promotes <i>ETV6-RUNX1</i> Precursor B-cell Leukemia via Impaired H3K4 Demethylases

, 2023
Guillermo Rodríguez-Hernández, Julia Hauer, Alberto Martín‐Lorenzo, Daniel Schäfer, Christoph Bartenhagen, Idoia García‐Ramírez, Franziska Auer, Inés González‐Herrero, Lucía Ruiz-Roca, Michael Gombert, Vera Okpanyi, Ute Fischer, Cai Chen, Martin Dugas, Sanil Bhatia, René Martin Linka, Marta Garcia-Suquia, María Victoria Rascón-Trincado, Ángel García-Sánchez, Óscar Blanco, Maria Begoña García-Cenador, Francisco Javier García‐Criado, César Cobaleda, Diego Alonso‐López, Javier De Las Rivas, Markus Müschen, Carolina Vicente‐Dueñas, Isidro Sánchez‐García, Arndt Borkhardt   +28 more
openalex   +1 more source

Demethylases Need PHDs♦ [PDF]

Journal of Biological Chemistry, 2010
openaire   +1 more source

Solamargine induces acute myeloid leukemia differentiation through TLR8 activation

VIEW, EarlyView.
SM, a steroidal alkaloid from Solanum nigrum L. has shown anticancer effect on various kinds of human cancer cells, yet its effect on leukemia cells remains unclear. This study examines antileukemic activities of SM in AML cells. Results indicate SM inhibits growth and promotes apoptosis of AML cells.
Qiaoyan Han, Yuting Chen, Zheyi Li, Yonglin Peng, Zhehan Hu, Yuliang Deng, Yanli Fu, Ming Cheng, Sheng Tan, Jing Tian, Xiaodong Zhao, Miao Sun   +11 more
wiley   +1 more source

Editorial: The emerging role of protein methylation/demethylation modification in disease and homeostasis

Frontiers in Molecular Biosciences
Yan-Jun Liu, Jian-Fei Lu, Xin Peng, Guan-Jun Yang   +3 more
doaj   +1 more source

Lysine demethylases 6 A and 6B as epigenetic regulators in therapeutic resistance of cancer. [PDF]

Clin Epigenetics
Yang L, Li H, Zhao Y, Qian Z, Luo G, Chen X, Yang X.   +6 more
europepmc   +1 more source

Data from Inhibition of the Histone H3K27 Demethylase UTX Enhances Tumor Cell Radiosensitivity

, 2023
Barbara H. Rath, Isabella Waung, Kevin Camphausen, Philip J. Tofilon   +3 more
openalex   +1 more source