Results 111 to 120 of about 97,922 (342)
Eye &ENT Research, EarlyView.Abstract Background Hearing loss, affecting 20% of the global population, disproportionately impacts low‐ and middle‐income countries, including Africa. Sensorineural hearing loss (SNHL) is prevalent among hemodialysis patients. In Tanzania, the growing number of hemodialysis patients highlights the need for hearing assessments.
Abdallah Jonas +6 more
wiley +1 more source
Scientific Reports, 2017 Cuprizone-induced demyelination in mice is a frequently used model in preclinical multiple sclerosis research. A recent quantitative clinically-targeted MRI method, fast macromolecular proton fraction (MPF) mapping demonstrated a promise as a myelin ...
M. Khodanovich +8 more
semanticscholar +1 more source
In silico modelling of neuron signal impact of cytokine storm-induced demyelination
Open BiologyIn this study, we develop an in silico model of a neuron’s behaviour under demyelination caused by a cytokine storm to investigate the effects of viral infections in the brain.
Geoflly L. Adonias +3 more
doaj +1 more source
Levamisol-induced leukoencephalopathy: clinical case
Анналы клинической и экспериментальной неврологии, 2018 This is a description of a clinical case of levamisole-induced leukoencephalopathy. A few hours after the single intake of the immunomodulator levamisole (150 mg), the patient developed following cerebral symptoms: febrile fever, dizziness, frequent ...
Olga A. Shavlovskaya
doaj +1 more source
Cause and prevention of demyelination in a model multiple sclerosis lesion
Annals of Neurology, 2016 Demyelination is a cardinal feature of multiple sclerosis, but it remains unclear why new lesions form, and whether they can be prevented. Neuropathological evidence suggests that demyelination can occur in the relative absence of lymphocytes, and with ...
R. Desai +6 more
semanticscholar +1 more source
Phase and Electron Microscopic Studies of Experimental Demyelination [PDF]
, 1961 Henry deF. Webster +3 more
openalex +1 more source
Epilepsy and systemic autoimmune diseases: A bidirectional two‐sample Mendelian randomization study
Epilepsia Open, EarlyView.Abstract Objective Epidemiological data indicates that individuals with epilepsy exhibit an elevated susceptibility to autoimmune disorders, and conversely, those with systemic autoimmune diseases (SAD) demonstrate a heightened predisposition to epilepsy.
Ruoshi Tian +4 more
wiley +1 more source
Анналы клинической и экспериментальной неврологии, 2017 Introduction. Cellular therapy of multiple sclerosis is currently considered to be one of the most promising treatment alternatives for this severe pathology of the nervous system. Materials and Methods.
Gennadiy N. Bisaga +5 more
doaj +1 more source
The dual S1PR1/S1PR5 drug BAF312 (Siponimod) attenuates demyelination in organotypic slice cultures
Journal of Neuroinflammation, 2016 BackgroundBAF312 (Siponimod) is a dual agonist at the sphingosine-1 phosphate receptors, S1PR1 and S1PR5. This drug is currently undergoing clinical trials for the treatment of secondary progressive multiple sclerosis (MS).
C. O’Sullivan +3 more
semanticscholar +1 more source
Demyelination in multiple sclerosis
, 2014 This review, focused on demyelination in multiple sclerosis, is divided in two parts. The first part addresses the many and not exclusive mechanisms leading to demyelination in the central nervous system. Although the hypothesis that a primary oligodendrocyte or myelin injury induces a secondary immune response in the central nervous system is still a ...
Bruno Stankoff, Catherine Lubetzki
openaire +2 more sources