Results 111 to 120 of about 104,217 (332)

Isolated seizures during the first episode of relapsing myelin oligodendrocyte glycoprotein antibody‐associated demyelination in children

Developmental Medicine & Child Neurology, 2018
Myelin oligodendrocyte glycoprotein (MOG) antibodies have a strong association with acute disseminated encephalomyelitis (ADEM) in children, and bilateral and recurrent optic neuritis in children and adults.
S. Ramanathan, G. O'grady, Stephen Malone, Claire G Spooner, D. Brown, D. Gill, F. Brilot, R. Dale   +7 more
semanticscholar   +1 more source

STING deficiency promotes motor recovery in mice following brachial plexus root avulsion

Animal Models and Experimental Medicine, EarlyView.
STING deficiency can increase the body weight, promote motor recovery, decrease MN death, inhibit pyroptosis and neuroinflammation, increase remyelination, and reduce the atrophy of the biceps brachii in mice with BPRA. Abstract Background Brachial plexus root avulsion (BPRA), a well‐known form of peripheral nerve injury, results in motor function loss
Yu Peng, Ying Zhang, Shenhui Yang, Lu He, Shuangxi Chen   +4 more
wiley   +1 more source

Attenuation of Experimental Autoimmune Demyelination in Complement-Deficient Mice [PDF]

, 2000
Serge Nataf, Steven L. Carroll, Rick A. Wetsel, Alexander J. Szalai, Scott R. Barnum   +4 more
openalex   +1 more source

In Vivo Measurement of Neurochemical Abnormalities in the Hippocampus in a Rat Model of Cuprizone-Induced Demyelination [PDF]

, 2020
Do‐Wan Lee, Jae‐Im Kwon, Chul‐Woong Woo, Hwon Heo, Kyung Won Kim, Dong‐Cheol Woo, Jeong Kon Kim, Dong‐Hoon Lee   +7 more
openalex   +1 more source

The complexity of dementia development and its comorbidities: The collaborative cross‐mouse population for multivarious tasks approach

Animal Models and Experimental Medicine, EarlyView.
The increasing prevalence of dementia and related neurodegenerative diseases—including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis—poses a growing public health challenge. These conditions have traditionally been studied as isolated central nervous system disorders, but emerging evidence points to ...
Osayd Zohud, Iqbal M. Lone, Kareem Midlej, Fuad A. Iraqi   +3 more
wiley   +1 more source

TRPV4 Inhibition Improved Myelination and Reduced Glia Reactivity and Inflammation in a Cuprizone-Induced Mouse Model of Demyelination

Frontiers in Cellular Neuroscience, 2018
The inhibition of demyelination and the promotion of remyelination are both considerable challenges in the therapeutic process for many central nervous system (CNS) diseases.
Meiying Liu, Xuan Liu, Lei Wang, Yu Wang, Fuxing Dong, Jian Wu, Xuebin Qu, Yanan Liu, Zhi’an Liu, Hong-bin Fan, Ruiqin Yao   +10 more
semanticscholar   +1 more source

Pro‐Inflammatory c‐Met+ CD4 T Cells in Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Hepatocyte growth factor (HGF) binds exclusively the c‐Met surface receptor, and the HGF/c‐Met axis regulates T cell function in autoimmune diseases. We analyzed c‐Met expression on human CD4 T cells in the blood and cerebrospinal fluid (CSF) from patients with multiple sclerosis (MS) versus non‐inflammatory neurological disease (NIND), to ...
Gautier Breville, Mahdia Benkhoucha, Ayman Rezk, Ngoc Lan Tran, Isis Senoner, Amit Bar‐Or, Patrice H. Lalive   +6 more
wiley   +1 more source

Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers

Journal of Lipid Research, 2003
The side chain oxidized oxysterol 24S-hydroxycholesterol (24-OH-chol) is formed almost exclusively in the brain, and there is a continuous passage of this oxysterol through the circulation to the liver.
Valerio Leoni, Thomas Masterman, Pria Patel, Steve Meaney, Ulf Diczfalusy, Ingemar Björkhem   +5 more
doaj   +1 more source

Behaviour of oligodendrocytes and Schwann cells in an experimental model of toxic demyelination of the central nervous system [PDF]

, 2001
Dominguita Lühers Graça, Eduardo Fernandes Bondan, Luís Antônio Violin Dias Pereira, Cristina Gevehr Fernandes, Paulo César Maiorka   +4 more
openalex   +1 more source

Demyelination and oligodendrocytes

Rinsho Shinkeigaku, 2011
Although neurological sequelae are attributable to poor regeneration of the central nervous system, oligodendrocytes demonstrate robust regenerative response even in adults. Accumulating evidence indicates that the glial cells identified by surface expression of the proteoglycan NG2 are the cellular source of newly-developed oligodendrocytes following ...
Takayuki, Itoh, Makoto, Horiuchi, Kouji, Wakayama, Aki, Itoh, David, Pleasure   +4 more
openaire   +3 more sources