Results 91 to 100 of about 72,285 (261)

AI‐Powered Gradient Echo Plural Contrast Imaging (AI‐GEPCI)—A Comprehensive Neurological Protocol From a Single MRI Scan

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background MRI is essential for diagnosing and monitoring neurological diseases. Conventional protocols require multiple sequences to obtain complementary contrasts, increasing scan time, cost, and tolerability. Generating multiple contrasts from a single acquisition may streamline workflow while maintaining clinical utility.
Jeramy Lewis   +8 more
wiley   +1 more source

Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng   +6 more
wiley   +1 more source

Hypoxic Neuroinflammation in the Pathogenesis of Multiple Sclerosis

open access: yesBrain Sciences
Multiple sclerosis (MS) is an autoimmune disease that damages the myelin sheath around the central nervous system axons, leading to neurological dysfunction.
Bethany Y. A. Hollingworth   +3 more
doaj   +1 more source

Personalized Treatment of Patients With Multiple Sclerosis: A Case Report and Literature Review

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Managing multiple sclerosis (MS) with a highly active disease course presents significant challenges, particularly regarding the timing of therapeutic escalation and the preservation of brain volume. We present a personalized management strategy for a 36‐year‐old male with relapsing‐remitting MS (RRMS) who experienced initial misdiagnosis ...
Fengjun Wang   +3 more
wiley   +1 more source

INVESTIGATING A TECHNOLOGY TO RESTORE SIGNAL TRANSMISSION ACROSS DEMYELINATED AXONS IN MULTIPLE SCLEROSIS: A COMPREHENSIVE REVIEW

open access: yesАвтоматизация технологических и бизнес-процессов
. Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by the degradation of myelin, a critical component of axons in the central nervous system (CNS).
Chathurika AGJ, Hettige B, Marikar FMMT
doaj   +1 more source

The Spectrum of Abnormal Tongue Movements: Review of Phenomenology, Etiology, and Differential Diagnosis

open access: yesMovement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Classifying abnormal tongue movements is challenging due to their varied presentations and limited visibility compared to other body parts. Accurate identification of the phenomenology guides physical examination and can point to specific diagnoses.
Nathaniel Bendahan   +4 more
wiley   +1 more source

Longest survivor of pulmonary atresia with ventricular septal defect without surgical intervention

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 1499-1507, April 2025.
Sang Zhou   +5 more
wiley   +1 more source

Early and Progressive Spinal Cord Atrophy in Spinocerebellar Ataxia Type 1

open access: yesMovement Disorders, EarlyView.
Abstract Background Spinocerebellar ataxia type 1 (SCA1) is a rare, autosomal dominant neurodegenerative disorder characterized by progressive cerebellar and brainstem degeneration. Previous studies have shown that spinal cord atrophy is also a key aspect of SCA1 neuropathology.
Colette J.M. Reniers   +11 more
wiley   +1 more source

A Severity‐Agnostic Atrophy Pattern in Spinocerebellar Ataxia Type 3: Volumetrics from ENIGMA‐Ataxia

open access: yesMovement Disorders, EarlyView.
Background Spinocerebellar ataxia type 3 (SCA3) is a rare, inherited neurodegenerative disease characterized by progressive loss of motor coordination. Objectives We undertook a multisite magnetic resonance imaging study to profile the spatial spread of atrophy across the brain, determine whether atrophy preferentially maps onto specific functional ...
Jason W. Robertson   +43 more
wiley   +1 more source

Transcranial Pulse Stimulation Enhances Dexterity in Parkinson's Disease: A Randomized Sham‐Controlled Trial

open access: yesMovement Disorders, EarlyView.
Abstract Background Ultrasound‐based neuromodulation, capable of reaching deep brain areas with high precision, represents cutting‐edge technology in non‐invasive brain stimulation and is investigated as a novel treatment for neurological and psychiatric disorders, including Parkinson's disease (PD).
Eva Matt   +14 more
wiley   +1 more source

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