Results 121 to 130 of about 70,292 (240)

Harmonic and power spectrum analysis of vertical ground reaction force in patients who have a stroke within 3 months

Experimental Physiology, EarlyView.
Abstract Stroke remains a primary cause of disability globally. An in‐depth comprehension of gait impairments following a stroke is vital for crafting effective therapeutic interventions, and vertical ground reaction forces (vGRF) provide valuable insights into these mechanics.
Li Zhang, Hongfang Yao, Shuisheng Fu, Jung Hung Chien   +3 more
wiley   +1 more source

Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation

Experimental Physiology, EarlyView.
Abstract Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS inflammation.
Mehrdad Nourizadeh, Amir Arsalan Ghahari, Ehsan Zandi, Seyedeh Zeynab Rasouli, Shaghayegh Davari, Mobina Hoseinzadeh, Mir Alireza Nourazar   +6 more
wiley   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Axon collateralization and focal myelin dystrophy alter action potential propagation in multicompartment pyramidal neuron models. [PDF]

PLoS Comput Biol
Sengupta N, Luebke JI, Weaver CM.
europepmc   +1 more source

Robust activity‐dependent mitochondrial calcium dynamics at the AIS is dispensable for action potential generation

The Journal of Physiology, EarlyView.
Abstract figure legend In cortical layer (L)5 pyramidal neurons we found that mitochondria in the axon initial segment (AIS) are distributed non‐uniformly and display robust calcium (Ca2+) uptake during action potential (AP) firing. Because the AIS is the site for the initiation of APs, which are shaped by cytosolic Ca2+ levels, we hypothesized that ...
Koen Kole, Maarten H.P. Kole
wiley   +1 more source

Demyelination and Cognitive Performance in Long COVID Patients with Insomnia and/or Depression. [PDF]

Int J Mol Sci
Khodanovich M, Kamaeva D, Usova A, Pashkevich V, Moshkina M, Obukhovskaya V, Kataeva N, Levina A, Tumentceva Y, Shadrina M, Ranzaeva A, Vasilieva S, Schastnyy E, Naumova A, Svetlik M.   +14 more
europepmc   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Editorial: Neuropathology of Autoimmune Inflammatory Demyelination Disorders

Frontiers in Neurology, 2022
Manuel Zeitelhofer, Sonja Hochmeister, Milena Z. Adzemovic, Milena Z. Adzemovic   +3 more
doaj   +1 more source

Pseudoathetotic Pseudodystonia as a Manifestation of Isolated Medullary Demyelination in Neuromyelitis Optica Spectrum Disorder. [PDF]

Tremor Other Hyperkinet Mov (N Y)
Mohapatra P, Hema LS, Mahadevan A, Garg D, Agarwal A, Pandit AK, Garg A, Srivastava AK, Radhakrishnan DM.   +8 more
europepmc   +1 more source

Demyelination [PDF]

, 2020
openaire   +1 more source