Results 121 to 130 of about 97,922 (342)

Abnormalities of thalamus and thalamocortical pathways in patients with refractory epilepsy caused by focal cortical dysplasia – MRI study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Drug‐resistant epilepsy, a severe and diagnostically challenging neurological condition often linked to focal cortical dysplasia (FCD), represents a significant social and healthcare burden. While the thalamus is notably altered in this disorder, it remains unclear whether these changes result from epilepsy manifestation or ...
David Kala   +12 more
wiley   +1 more source

AAV‐Based Intracerebral Administration of BDNF Promotes Myelin Repair and Cognitive Improvement After Cuprizone‐Induced Demyelination

open access: yesGlia, EarlyView.
AAV‐BDNF improves cognitive performance after cuprizone‐induced de‐myelination. BDNF promotes OPC maturation and enhances remyelination in the corpus callosum. Mitochondrial integrity is preserved through reduced swelling and improved morphology. ABSTRACT Multiple sclerosis (MS) is a chronic neurological disorder involving immune‐mediated demyelination
Yousra El Ouaamari   +14 more
wiley   +1 more source

Increased levels of myelin basic protein transcripts gene in virus-induced demyelination [PDF]

open access: bronze, 1986
Krister Kristensson   +5 more
openalex   +1 more source

Reduced Accumulation Rate and Morphological Changes of Newly Generated Myelinating Oligodendrocytes in the Corpus Callosum of Aged Mice

open access: yesGlia, EarlyView.
Newly generated myelinating oligodendrocyte accumulation is decreased in the corpus callosum of aged mice. Morphological changes of newly generated myelinating oligodendrocytes in aged mice: greater height, shorter, and fewer myelin sheaths. ABSTRACT The activity of oligodendrocyte progenitor cells (OPCs) and oligodendrocytes (OLs) throughout life ...
Sasikarn Looprasertkul   +3 more
wiley   +1 more source

The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance

open access: yesGlia, EarlyView.
Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons during rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic lipids and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production of ...
Rose Follis   +2 more
wiley   +1 more source

Prolactin Receptor Deficiency Promotes Hypomyelination in White Matter Tracts During Postnatal Central Nervous System Maturation in Mice

open access: yesGlia, EarlyView.
Prolactin action is essential for proper myelination of white matter tracts during neonatal and prepubertal stages in mice. Lack of prolactin receptor (Prlr−/−) signaling leads to hypomyelination and impaired locomotor function. ABSTRACT A large wave of myelination in the central nervous system (CNS) of mammals occurs during postnatal development ...
Ana L. Ocampo‐Ruiz   +12 more
wiley   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

open access: yesIbrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo   +7 more
wiley   +1 more source

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