Results 131 to 140 of about 70,292 (240)

The Ubiquitin Ligase Zinc Finger SWIM Domain‐Containing Protein 8 Regulates Oligodendrocyte Development Through the Argonaute2/MicroRNA‐7 Axis

Glia, Volume 74, Issue 5, May 2026.
ZSWIM8, an E3 ubiquitin ligase that broadly targets IDR‐rich proteins, drives MiR‐7‐dependent AGO2 degradation and the turnover of many RBPs. Loss of ZSWIM8 leads to MiR‐7 accumulation in oligodendrocyte progenitor cells and myelination defects in the developing brain. ABSTRACT Proteostasis of proteins with intrinsically disordered regions (IDRs) is of
Jing Lei, Siming Zhong, Rong Fan, Xin Shu, Guan Wang, Jiansheng Guo, Shuting Xue, Luqian Zheng, Aiming Ren, Junfang Ji, Bing Yang, Shumin Duan, Zhiping Wang, Xing Guo   +13 more
wiley   +1 more source

Osmotic demyelination syndrome after liver transplantation: A case report and an updated review. [PDF]

Saudi J Anaesth
Wu X, Wang J, Shi X, Wu J, Mu S, Gong M.
europepmc   +1 more source

MC BTS: Simultaneously Resolving Magnetization Transfer Effect and Relaxation for Multiple Components

Magnetic Resonance in Medicine, Volume 95, Issue 5, Page 2538-2553, May 2026.
ABSTRACT Purpose To propose a signal acquisition and modeling framework for multi‐component tissue quantification that encompasses transmit field inhomogeneity, multi‐component relaxation and magnetization transfer (MT) effects. Theory and Methods By applying off‐resonance irradiation between excitation and acquisition within an RF‐spoiled gradient ...
Albert Jang, Hyungseok Jang, Nian Wang, Alexey Samsonov, Fang Liu   +4 more
wiley   +1 more source

Temporal Dynamics of CNS Cholesterol Esters Correlate with Demyelination and Remyelination. [PDF]

ACS Chem Neurosci
De Silva Mohotti N, Williams JM, Binjawadagi R, Kobayashi H, Dedunupitiya D, Petersen JM, Garcia A, Hartley MD.   +7 more
europepmc   +1 more source

Technical Review of Magnetic Resonance Fingerprinting Applications in Cerebral Physiology

Magnetic Resonance in Medicine, Volume 95, Issue 5, Page 2898-2918, May 2026.
ABSTRACT Magnetic resonance fingerprinting (MRF) enables quantitative MRI by allowing the simultaneous mapping of multiple tissue properties through innovative acquisition and computational methods. This review focuses on the application of MRF techniques to cerebral physiology, emphasizing advancements in vascular imaging and the integration of ...
Chieh‐Te Lin, Hanzhang Lu, Audrey P. Fan   +2 more
wiley   +1 more source

Fisetin Mitigates Ferroptosis and Promotes Remyelination in a Cuprizone Model of Multiple Sclerosis. [PDF]

J Neuroimmune Pharmacol
El-Ashmawy NE, Khedr NF, Helmy NN, Ibrahim AO.   +3 more
europepmc   +1 more source

Accelerating Multiparametric Quantitative MRI Using Self‐Supervised Scan‐Specific Implicit Neural Representation With Model Reinforcement

Magnetic Resonance in Medicine, Volume 95, Issue 5, Page 2963-2979, May 2026.
ABSTRACT Purpose To develop a self‐supervised scan‐specific deep learning framework for reconstructing accelerated multiparametric quantitative MRI (qMRI). Methods We propose REFINE‐MORE (REference‐Free Implicit NEural representation with MOdel REinforcement), combining an implicit neural representation (INR) architecture with a model reinforcement ...
Ruimin Feng, Albert Jang, Xingxin He, Fang Liu   +3 more
wiley   +1 more source

Informed Dictionary‐Guided Monte Carlo Inversion for Robust and Reproducible Multidimensional MRI

Magnetic Resonance in Medicine, Volume 95, Issue 5, Page 2947-2962, May 2026.
ABSTRACT Purpose To develop a robust and efficient multidimensional MRI (MD‐MRI) data processing framework for accurately estimating joint frequency‐dependent diffusion‐relaxation distributions, while overcoming computational limitations and noise instability inherent to Monte Carlo (MC) inversion.
Joon Sik Park, Eppu Manninen, Yihong Yang, Dan Benjamini   +3 more
wiley   +1 more source

Osmotic demyelination syndrome diagnosed by Magnetic Resonance Imaging in a child with tetraplegia: Case report. [PDF]

Radiol Case Rep
Domruk ÖF, Almus E, Yılmaz Z, Yapıcı Ö.   +3 more
europepmc   +1 more source

Spatial Image Gradient Estimation From the Diffusion MRI Profile

Magnetic Resonance in Medicine, Volume 95, Issue 5, Page 2980-2991, May 2026.
ABSTRACT Purpose In the course of diffusion, water molecules encounter varying values for the relaxation‐time properties of the underlying tissue. This factor, which has rarely been accounted for in diffusion MRI (dMRI), is modeled in this work, allowing for the estimation of the gradient of relaxation‐time properties from the dMRI signal. Methods With
Iman Aganj, Thorsten Feiweier, John E. Kirsch, Bruce R. Fischl, Andre J. van der Kouwe   +4 more
wiley   +1 more source