Results 181 to 190 of about 70,292 (240)

Immunoaffinity‐Mimetic Assembly of Peptide‐Aptamer Conjugates and Stem Cell‐Derived Exosomes into Hierarchical Microgels for Spinal Cord Injury Repair

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
Inspired by antibody‐antigen binding, this study develops an unprecedented immunoaffinity‐mimetic assembly strategy, with Peptide‐AptCD63 conjugates acting as antibody surrogates binding CD63 epitopes on mesenchymal stem cell‐derived exosomes. This creates a hierarchical microstructure intended to synergistically integrate antioxidative and anti ...
Dantong Zheng   +8 more
wiley   +1 more source

Engineering Cadherin‐Guided MSC Aggregates to Empower Synergistic Neurovascular Repair After Stroke

open access: yesAggregate, Volume 7, Issue 3, March 2026.
A cadherin‐directed bioengineering strategy transforms mesenchymal stem cell aggregation from passive clustering into active functional programming. The resulting cadherin‐guided aggregates exhibit reinforced microstructure, stress resistance, and an enhanced pro‐regenerative secretome, enabling coordinated neurovascular repair in ischemic stroke.
Guoqiang Chen   +8 more
wiley   +1 more source

In vivo mapping of cortical amyloid beta‐myelin coupling in preclinical Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Accumulating evidence suggests that amyloid‐β (Aβ) preferentially deposits in poorly myelinated cortical regions and may interfere with remyelination. We hypothesized that this vulnerability would manifest as altered Aβ–myelin coupling in preclinical Alzheimer's disease (AD).
Mercedes Atienza, Jose L. Cantero
wiley   +1 more source

Endogenous Repair in Vanishing White Matter

open access: yesAnnals of Neurology, Volume 99, Issue 3, Page 737-747, March 2026.
[Color figure can be viewed at www.annalsofneurology.org] Objective Vanishing white matter is a leukodystrophy with remarkable regional variation in disease severity. The cerebral and cerebellar white matter chronically degenerates, while stress‐induced episodes of rapid neurological deterioration coincide with the appearance of acute focal lesions in ...
Bonnie C. Plug   +7 more
wiley   +1 more source

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